| Protein: | pik3 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 801 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pik3.
| Description | E-value | Query Range |
Subject Range |
|
|
782.0 | [0..1] | [801..1] |
|
|
769.0 | [0..6] | [800..6] |
|
|
765.0 | [0..6] | [800..6] |
|
|
764.0 | [0..6] | [800..6] |
|
|
757.0 | [0..6] | [800..6] |
|
|
754.0 | [0..6] | [800..6] |
|
|
741.0 | [0..6] | [800..6] |
|
Region A: Residues: [1-801] |
1 11 21 31 41 51
| | | | | |
1 MDRLVFSYCP SSKVTARFLV KFCFIEYQDS QEPCICTIQL FSGNESGSLM QKCFVSKIPN 60
61 KSLLPTELSK ISTHEWLDFG VTVSELSLNA KFVVSAWKPS FNDEEVYEFV GCTTYRLFDE 120
121 NNLLRQGLQK IPLQTSKEIK KYSPTSLELE QVKEINRLDG LLLKLQLGDV PSVNWLDDIS 180
181 FGKIKDFRSK HMSLVTIPIL YLDFLQFSFP VVFQRSYYPK SENRVYYSSF DLELNLDSPA 240
241 ELKHRRLVRS QRNGPLDKDL KPNSKIRKEL ESILSYPPSE ELSLEEKDLI WKFRFYLTRN 300
301 KKAMTKFLKS VVWTDSSEVN QALSLLDSWT EIDIDDALEL LSPSFVHPKV RAYAVSRLET 360
361 ASNEELLLYL LQLVQALRYD NPISSDERFQ PSPLALFLVN RAISSPSIGN DLYWYLVVEI 420
421 EDEPVSKLFS SVMFLFQKEL SKSVEGRLIR ETLSAQAKFV EKLLRISKSV QSFRGTRLKK 480
481 IEYLKVLLED HKYHLLDFHA LPLPLDPSVN IVGIIPDACT VFKSTMQPLR LLFKCQDGSK 540
541 YPIIFKNGDD LRQDQLVIQI LTLMDKLLKK EKLDLHLKPY RILATGPTHG AVQFVPSKTL 600
601 ATILAEYHGS VLAYLRENNP DDGLNSANYG IDPVAMDNYV RSCAGYCVIT YLLGVGDRHL 660
661 DNLLITKDGH FFHADFGYIL GRDPKLFSPA MKLSKEMVEG MGGYNSPFYQ QFKSYCYTTF 720
721 TALRKSSNLI LNLFSLMVDA NIPDIKFDKE KVVYKVKERF CLQMSESDAI KYFEQLINDS 780
781 VSALFPQIID RMHNLAQYMR S
|
| Detection Method: |  |
| Confidence: | 163.0 |
| Match: | 1he8A |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 1-phosphatidylinositol-3-kinase activity | 8.12544462052019 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase activity | 8.10715314025226 | bayes_pls_golite062009 |
| lipid kinase activity | 5.98454599133418 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol kinase activity | 5.59422890717019 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| protein kinase activity | 5.17195961442593 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity | 4.51744163880238 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| calcium-dependent phospholipid binding | 2.37116581763683 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.36057410204148 | bayes_pls_golite062009 |
| binding | 2.31930216202447 | bayes_pls_golite062009 |
| profilin binding | 2.1052288288978 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.97522797979421 | bayes_pls_golite062009 |
| molecular transducer activity | 1.95775692939268 | bayes_pls_golite062009 |
| signal transducer activity | 1.95775692939268 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.63027742934354 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 1.4515576307774 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| neurexin binding | 1.37902741014529 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.27941426224024 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 1.27740808551012 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| receptor activity | 1.13726344123824 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.96468055729151 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.58590430118616 | bayes_pls_golite062009 |
| signal sequence binding | 0.57106697498903 | bayes_pls_golite062009 |
| MAP kinase activity | 0.5066845540941 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.451090007290896 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| clathrin binding | 0.35775052108553 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| protein complex binding | 0.265979208658691 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.252495966234234 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.205652638854091 | bayes_pls_golite062009 |
| nuclear localization sequence binding | 0.200784507667389 | bayes_pls_golite062009 |
| hydrolase activity | 0.056449407710228 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 0.00492507437049428 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
| protein tag | 0.00311613478935058 | bayes_pls_golite062009 |
