Protein: | tup12 |
Organism: | Schizosaccharomyces pombe |
Length: | 586 amino acids |
Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tup12.
Description | E-value | Query Range |
Subject Range |
|
433.0 | [0..68] | [582..598] |
|
428.0 | [0..38] | [585..959] |
|
419.0 | [0..43] | [583..581] |
|
413.0 | [0..66] | [583..979] |
|
411.0 | [0..76] | [581..165] |
Region A: Residues: [1-126] |
1 11 21 31 41 51 | | | | | | 1 MITVRQFTFT IFKFQFMATS NVSSRVNELL EAVKKEFEDI CQKTKTVEAQ KDDFEYKAMI 60 61 SAQINEMALM KQTVMDLEMQ QSKVKDRYEE EITSLKAQLE ARRKEIASGV VPQSSKTKHG 120 121 RNSVSF |
Detection Method: | ![]() |
Confidence: | 1.25 |
Match: | 1jchA |
Description: | Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [127-212] |
1 11 21 31 41 51 | | | | | | 1 GKYGNAGPFN SDNSSKPLIL NNGSSGGTPK NLRSPAIDSD GTVLAPIQTS NVDLGSQYYS 60 61 SPHVRPAVGA TMAGSAMRTF PSNLPL |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [213-275] |
1 11 21 31 41 51 | | | | | | 1 GHPPPPSDSA NSSVTPIAAP LVVNGKVSGN PPYPAEIIPT SNVPNREEKD WTVTSNVPNK 60 61 EPP |
Detection Method: | ![]() |
Confidence: | 7.0 |
Match: | 1crzA |
Description: | TolB, C-terminal domain; TolB, N-terminal domain |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [276-586] |
1 11 21 31 41 51 | | | | | | 1 ISVQLLHTLE HTSVICYVRF SADGKFLATG CNRAAMVFNV ETGKLITLLQ EESSKREGDL 60 61 YVRSVAFSPD GKYLATGVED QQIRIWDIAQ KRVYRLLTGH EQEIYSLDFS KDGKTLVSGS 120 121 GDRTVCLWDV EAGEQKLILH TDDGVTTVMF SPDGQFIAAG SLDKVIRIWT SSGTLVEQLH 180 181 GHEESVYSVA FSPDGKYLVS GSLDNTIKLW ELQCVSNVAP SMYKEGGICK QTFTGHKDFI 240 241 LSVTVSPDGK WIISGSKDRT IQFWSPDSPH SQLTLQGHNN SVISVAVSPN GHCFATGSGD 300 301 LRARIWSYED L |
Detection Method: | ![]() |
Confidence: | 60.39794 |
Match: | 1erjA |
Description: | Tup1, C-terminal domain |
Matching Structure (courtesy of the PDB):![]() |
Term | Confidence | Notes |
6.67009948605948 | bayes_pls_golite062009 | |
histone methyltransferase activity (H3-K4 specific) | 4.71992275913384 | bayes_pls_golite062009 |
myosin heavy chain kinase activity | 4.33124151198369 | bayes_pls_golite062009 |
GTPase activity | 4.02994814377904 | bayes_pls_golite062009 |
actin binding | 3.86142918698875 | bayes_pls_golite062009 |
acetyltransferase activity | 3.85374902981345 | bayes_pls_golite062009 |
RNA binding | 3.77273677738815 | bayes_pls_golite062009 |
myosin II binding | 3.56132510021228 | bayes_pls_golite062009 |
acyltransferase activity | 3.35098520158193 | bayes_pls_golite062009 |
transferase activity, transferring acyl groups other than amino-acyl groups | 3.31615347567536 | bayes_pls_golite062009 |
S-adenosylmethionine-dependent methyltransferase activity | 3.25521258308263 | bayes_pls_golite062009 |
transferase activity, transferring acyl groups | 3.14917998298348 | bayes_pls_golite062009 |
cytoskeletal protein binding | 3.1056443224755 | bayes_pls_golite062009 |
general RNA polymerase II transcription factor activity | 2.99343906593123 | bayes_pls_golite062009 |
tubulin binding | 2.76945430061825 | bayes_pls_golite062009 |
microtubule binding | 2.72684103222924 | bayes_pls_golite062009 |
structural molecule activity | 2.6914565031145 | bayes_pls_golite062009 |
dynein binding | 2.54821997913979 | bayes_pls_golite062009 |
binding | 2.42570478946173 | bayes_pls_golite062009 |
transcription regulator activity | 2.3610959773142 | bayes_pls_golite062009 |
nucleic acid binding | 2.30918780727915 | bayes_pls_golite062009 |
transcription repressor activity | 2.29049708962212 | bayes_pls_golite062009 |
snoRNA binding | 2.27164613239345 | bayes_pls_golite062009 |
protein binding | 2.26925404328312 | bayes_pls_golite062009 |
G-protein-coupled receptor binding | 2.10926890165617 | bayes_pls_golite062009 |
dynactin binding | 2.07556426531897 | bayes_pls_golite062009 |
actin filament binding | 2.0735069176589 | bayes_pls_golite062009 |
histone methyltransferase activity | 1.85632145559025 | bayes_pls_golite062009 |
DNA binding | 1.71685536470455 | bayes_pls_golite062009 |
receptor activity | 1.69781740346574 | bayes_pls_golite062009 |
phosphotransferase activity, alcohol group as acceptor | 1.5281054405163 | bayes_pls_golite062009 |
kinase activity | 1.5053563627859 | bayes_pls_golite062009 |
telomerase activity | 1.44665328127499 | bayes_pls_golite062009 |
molecular transducer activity | 1.42581655945599 | bayes_pls_golite062009 |
signal transducer activity | 1.42581655945599 | bayes_pls_golite062009 |
transcription corepressor activity | 1.41752877005447 | bayes_pls_golite062009 |
protein methyltransferase activity | 1.35170368882651 | bayes_pls_golite062009 |
transferase activity, transferring phosphorus-containing groups | 1.33036729957356 | bayes_pls_golite062009 |
protein kinase activity | 1.3214585007945 | bayes_pls_golite062009 |
transporter activity | 1.21549336905926 | bayes_pls_golite062009 |
histone-lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
protein-lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
RNA-directed DNA polymerase activity | 1.10560669001943 | bayes_pls_golite062009 |
transcription factor activity | 1.08768505897883 | bayes_pls_golite062009 |
mRNA binding | 1.05053985350578 | bayes_pls_golite062009 |
microtubule plus-end binding | 1.01166033978052 | bayes_pls_golite062009 |
myosin binding | 0.989691178611801 | bayes_pls_golite062009 |
protein transporter activity | 0.964340340346761 | bayes_pls_golite062009 |
type 1 angiotensin receptor binding | 0.920323565472959 | bayes_pls_golite062009 |
angiotensin receptor binding | 0.920323565472959 | bayes_pls_golite062009 |
transferase activity | 0.913674310517261 | bayes_pls_golite062009 |
substrate-specific transporter activity | 0.734793983890004 | bayes_pls_golite062009 |
histone binding | 0.685319917508843 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 0.676924760416604 | bayes_pls_golite062009 |
transcription initiation factor activity | 0.656824577987243 | bayes_pls_golite062009 |
DNA-dependent ATPase activity | 0.625780732991652 | bayes_pls_golite062009 |
protein serine/threonine kinase activity | 0.618638900707402 | bayes_pls_golite062009 |
transcription factor binding | 0.489473003915035 | bayes_pls_golite062009 |
dynein intermediate chain binding | 0.443846546939402 | bayes_pls_golite062009 |
insulin receptor binding | 0.43316396073854 | bayes_pls_golite062009 |
peptide binding | 0.387345823168967 | bayes_pls_golite062009 |
transcription cofactor activity | 0.30761651528651 | bayes_pls_golite062009 |
nucleotidyltransferase activity | 0.28606552120995 | bayes_pls_golite062009 |
DNA helicase activity | 0.220747580531792 | bayes_pls_golite062009 |
enzyme regulator activity | 0.161639372576406 | bayes_pls_golite062009 |
chromatin binding | 0.151977098745772 | bayes_pls_golite062009 |
structural constituent of cytoskeleton | 0.118975415284669 | bayes_pls_golite062009 |
receptor binding | 0.0390635451962911 | bayes_pls_golite062009 |
kinase binding | 0.0366162235750993 | bayes_pls_golite062009 |
protein kinase binding | 0.00858004043229577 | bayes_pls_golite062009 |
nucleoside-triphosphatase activity | 0.00585398682921312 | bayes_pls_golite062009 |
N-methyltransferase activity | 0.00335766408304172 | bayes_pls_golite062009 |