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View Structure Prediction Details

Protein: klp6
Organism: Schizosaccharomyces pombe
Length: 784 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for klp6.

Description E-value Query
Range		 Subject
Range
gi|109505592 - gi|109505592|ref|XP_001058501.1| PREDICTED: similar to Kinesin-like protein KIF13A [Rattus norvegicu...
 343.0 [0..14] [778..218]
gi|157170176 - gi|157170176|gb|AAI52808.1| Kinesin family member 1B [synthetic construct]
gi|123209319, gi... - gi|86990460|ref|NP_997565.2| kinesin family member 1B isoform b [Mus musculus], gi|187465979|emb|CAQ...
 339.0 [0..53] [717..5]
gi|66347394, gi|... - gi|66347734|emb|CAI95220.1| kinesin family member 1B [Homo sapiens], gi|66347394|emb|CAI95752.1| kin...
 336.0 [0..53] [717..5]

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Predicted Domain #1
Region A:
Residues: [1-414] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEGSSISVA VRVRPFTERE KGLLAETPKS KEFLGDGSLA VSNTSSNTFC TNGIRKIVRV  60
   61 LDDNVLIFDP PEENPLAKVQ KSLLPAGKRF RDVRYAFDRL FGEEASQEDV YKGTTEPLLD 120
  121 SVLQGYNATV FAYGATGCGK THTISGRPDD PGIIFLTMRA LLDRVEGLKR TMNVDISVSY 180
  181 LEIYNEKIRD LLVQDPLSME KPKSLNICED AEQNVSVPGL SYFTPTNLEE VMEIIIRGNS 240
  241 NRTMSPTEAN AVSSRSHAVL QIYITQTPKS GEKQEESESQ NSHKVRSVFS FIDLAGSERA 300
  301 SATKNRGKRL VEGANINRSL LALGNCINSL CEPRRRQHVP YRDSKLTRLL KFSLGGNCRT 360
  361 CMIVCISPSS EHYDETHNTL KYGNRAKNIK TKVSRNVVSV DRHVSEYVRT IYEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.0
Match: 1gojA
Description: Kinesin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 7.68336791348661 bayes_pls_golite062009
plus-end-directed microtubule motor activity 4.97507344344589 bayes_pls_golite062009
microfilament motor activity 4.176620576177 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
actin-dependent ATPase activity 2.77140616759165 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
DNA-dependent ATPase activity 2.58390156971125 bayes_pls_golite062009
transporter activity 2.58140740499725 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
transmembrane transporter activity 2.39695871109024 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
actin binding 2.2973522188675 bayes_pls_golite062009
ATPase activity, coupled 2.18396165590908 bayes_pls_golite062009
DNA helicase activity 1.72320119360938 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.52935820732225 bayes_pls_golite062009
microtubule plus-end binding 1.36713729043205 bayes_pls_golite062009
substrate-specific transporter activity 1.29730375126024 bayes_pls_golite062009
actin filament binding 1.28204719195916 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.906554174337376 bayes_pls_golite062009
helicase activity 0.79055709374547 bayes_pls_golite062009
nucleic acid binding 0.777787753097919 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.724847255896311 bayes_pls_golite062009
translation regulator activity 0.68989258674288 bayes_pls_golite062009
protein-DNA loading ATPase activity 0.654899784430321 bayes_pls_golite062009
kinetochore binding 0.534490088080411 bayes_pls_golite062009
DNA binding 0.479412476059825 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
guanyl nucleotide binding 0.399434758448606 bayes_pls_golite062009
GTP binding 0.398333597279278 bayes_pls_golite062009
guanyl ribonucleotide binding 0.39332178627529 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
ion transmembrane transporter activity 0.355466224802969 bayes_pls_golite062009
transcription regulator activity 0.312171320541728 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
translation release factor activity 0.244766426029311 bayes_pls_golite062009
DNA clamp loader activity 0.234068677215771 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
translation termination factor activity 0.217935722994764 bayes_pls_golite062009
protein transporter activity 0.178442534411253 bayes_pls_golite062009
centromeric DNA binding 0.120185906020979 bayes_pls_golite062009
minus-end-directed microtubule motor activity 0.068779631341469 bayes_pls_golite062009
structure-specific DNA binding 0.0463883764000663 bayes_pls_golite062009
cation transmembrane transporter activity 0.0254369227200564 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [415-784] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQKVSILQKR IAEESKQLAL NKEVRKISSR EIKMLDARSM LKNSFDGSRD LQKSLIEHVR  60
   61 TLRRIEDEIT LTKMWISIAK ESDAMSGHNI KSVETRLAKL YDQRSLITAK VNPEEICKTF 120
  121 QNSISHIVSS FKGEGADMYA DMLQDDVDLL KSIIENQILD AKHESETFSS TSRKLIQNLF 180
  181 LLFPLLPGNA IDVNESLARA FDQLVGIVPS EPTIQVPNLI EKGKAPLLSM FEIPRSPSRF 240
  241 KARSPSKAAR VLKKPLKKRV RFSEVPTTSS VPPVEIKNKD SKPKVEKSLD KHNMNNDRSF 300
  301 LVPSRDARNS LTSLSLHSNV AKNKSSHSSK WPTHTLSPII TTALKQPVRR ISLVSQPLQK 360
  361 TGGTENTPNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.39794
Match: 2dfsA
Description: No description for 2dfsA was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle