YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC1198.05
Organism:	Schizosaccharomyces pombe
Length:	202 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC1198.05.

Description	E-value	Query Range	Subject Range
gi\|52784220, gi\|... - gi\|52784220\|ref\|YP_090049.1\| hypothetical protein BLi00398 [Bacillus licheniformis ATCC 14580], gi\|5...	202.0	[0..9]	[198..20]
gi\|88865115, gi\|... - gi\|89055566\|ref\|YP_511017.1\| ABC transporter related [Jannaschia sp. CCS1], gi\|88865115\|gb\|ABD55992....	200.0	[0..10]	[201..22]
gi\|27382307, gi\|... - gi\|27382307\|ref\|NP_773836.1\| ABC transporter ATP-binding protein [Bradyrhizobium japonicum USDA 110]...	200.0	[0..10]	[201..41]
gi\|15073645 - gi\|15073645\|emb\|CAC45287.1\| Probable putrescine transport ATP-binding protein [Sinorhizobium melilot... gi\|15964468 - gi\|15964468\|ref\|NP_384821.1\| putrescine ABC transporter ATP-binding protein [Sinorhizobium meliloti ...	200.0	[0..5]	[201..36]
gi\|221236171, gi... - gi\|221236171\|ref\|YP_002518608.1\| spermidine/putrescine transport ATP-binding protein potA [Caulobact... gi\|25384753 - pir\|\|D87637 hypothetical protein CC3134 [imported] - Caulobacter crescentus gi\|16127364, gi\|... - gi\|16127364\|ref\|NP_421928.1\| spermidine/putrescine ABC transporter, ATP-binding protein [Caulobacter...	200.0	[0..10]	[201..32]
gi\|113726386, gi... - gi\|150395538\|ref\|YP_001326005.1\| spermidine/putrescine ABC transporter ATPase subunit [Sinorhizobium...	198.0	[0..5]	[201..35]
gi\|89344434, gi\|... - gi\|89899697\|ref\|YP_522168.1\| ABC transporter related [Rhodoferax ferrireducens T118], gi\|89344434\|gb...	198.0	[0..12]	[202..31]
gi\|228899963, gi... - gi\|228899963\|ref\|ZP_04064202.1\| Spermidine/putrescine import ATP-binding protein potA [Bacillus thur... gi\|229043124, gi... - gi\|229043124\|ref\|ZP_04190851.1\| Spermidine/putrescine import ATP-binding protein potA [Bacillus cere... gi\|228964341, gi... - gi\|228964341\|ref\|ZP_04125459.1\| Spermidine/putrescine import ATP-binding protein potA [Bacillus thur... gi\|218232537, gi... - gi\|218232537\|ref\|YP_002366068.1\| spermidine/putrescine ABC transporter, ATP-binding protein [Bacillu... gi\|228801997, gi... - gi\|228957655\|ref\|ZP_04119402.1\| Spermidine/putrescine import ATP-binding protein potA [Bacillus thur... gi\|218896317, gi... - gi\|218896317\|ref\|YP_002444728.1\| spermidine/putrescine ABC transporter, ATP-binding protein [Bacillu... gi\|228839553, gi... - gi\|228920097\|ref\|ZP_04083446.1\| Spermidine/putrescine import ATP-binding protein potA [Bacillus thur... gi\|229149585, gi... - gi\|229149585\|ref\|ZP_04277817.1\| Spermidine/putrescine import ATP-binding protein potA [Bacillus cere... gi\|228639386, gi... - gi\|229143989\|ref\|ZP_04272405.1\| Spermidine/putrescine import ATP-binding protein potA [Bacillus cere... gi\|228656640, gi... - gi\|229126700\|ref\|ZP_04255712.1\| Spermidine/putrescine import ATP-binding protein potA [Bacillus cere... POTA_BACCR - Spermidine/putrescine import ATP-binding protein PotA OS=Bacillus cereus (strain ATCC 14579 / DSM 31... gi\|229108840, gi... - gi\|229108840\|ref\|ZP_04238445.1\| Spermidine/putrescine import ATP-binding protein potA [Bacillus cere...	198.0	[0..12]	[201..24]
gi\|89349159, gi\|... - gi\|89362113\|ref\|ZP_01199924.1\| Spermidine/putrescine ABC transporter ATP-binding subunit [Xanthobact...	198.0	[0..5]	[201..42]
POTA_MARHV - Spermidine/putrescine import ATP-binding protein PotA OS=Marinobacter hydrocarbonoclasticus (strain ...	198.0	[0..12]	[201..25]

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Predicted Domain #1

Region A:
Residues: [1-202]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPQLSSSVA SKLVTLKLKP VVVFGPSGVG KSTLLKRLLK DHGDKLGFSV SHTTRTPRAG  60
   61 EKDGIDYHFV TKEEFQKLVA EEKFVEWAVF SGNMYGTSIM AIQELEAVNK KAILDIDLQG 120
  121 VLQVKASPID AQYVFLAPPS IEQLEVRLRG RGTENESAIL QRLERARAEI EYSEKPGNFD 180
  181 ALIVNDDVEK AYKQLEAICL SD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.09691
Match:	1lvgA
Description:	Guanylate kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transporting ATP synthase activity, rotational mechanism	4.94368959158184	bayes_pls_golite062009
GTPase activity	4.06265232661098	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	4.00431985024242	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	3.88411242531695	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	3.66392587433723	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
primary active transmembrane transporter activity	2.61775212528604	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.61467977505707	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57552435627908	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57107347424517	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57054427875021	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
ATPase activity, coupled	2.43862163407966	bayes_pls_golite062009
motor activity	2.40267948113603	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
nucleotide kinase activity	2.24094813695083	bayes_pls_golite062009
glutamate receptor binding	2.18149167417819	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	1.96697952975573	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
microtubule motor activity	1.77441050776692	bayes_pls_golite062009
hydrolase activity	1.57549510726226	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.56325751172863	bayes_pls_golite062009
cytoskeletal protein binding	1.50574672650697	bayes_pls_golite062009
nucleic acid binding	1.08697924060619	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
guanylate kinase activity	0.98934362137863	bayes_pls_golite062009
ion transmembrane transporter activity	0.977237423302079	bayes_pls_golite062009
signal transducer activity	0.952448314982579	bayes_pls_golite062009
molecular transducer activity	0.952448314982579	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
peptide-transporting ATPase activity	0.911425383309011	bayes_pls_golite062009
actin binding	0.875514430441177	bayes_pls_golite062009
peptide transporter activity	0.73541731084591	bayes_pls_golite062009
DNA binding	0.702147676354075	bayes_pls_golite062009
cation transmembrane transporter activity	0.557919489256916	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	0.48775834126327	bayes_pls_golite062009
adenylate kinase activity	0.447752711852745	bayes_pls_golite062009
microfilament motor activity	0.415173945174069	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
transcription regulator activity	0.312171320541728	bayes_pls_golite062009
receptor activity	0.277332279568238	bayes_pls_golite062009
tubulin binding	0.264882086048416	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	0.25714006331445	bayes_pls_golite062009
transmembrane receptor activity	0.243026482777117	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	0.20818362273204	bayes_pls_golite062009
protein binding	0.170837278876362	bayes_pls_golite062009
microtubule binding	0.156470772916507	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.123304946374679	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.0775601177068852	bayes_pls_golite062009
helicase activity	0.0775311459068899	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: