YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: FBpp0292319, ttk...
Organism: Drosophila melanogaster
Length: 813 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0292319, ttk....

Description E-value Query
Range
Subject
Range
gi|76648475 - gi|76648475|ref|XP_881780.1| PREDICTED: similar to Zinc finger protein 197 (ZnF20) isoform 3 [Bos ta...
609.0 [0..87] [802..367]

Back

Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMASQRFCL RWNNHQSNLL SVFDQLLHAE TFTDVTLAVE GQHLKAHKMV LSACSPYFNT  60
   61 LFVSHPEKHP IVILKDVPYS DMKSLLDFMY RGEVSVDQER LTAFLRVAES LRIKGLTEVN 120
  121 DDKPSPAAAA AGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 1r28A
Description: Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.03732153795237 bayes_pls_golite062009
DNA binding 3.50992893425527 bayes_pls_golite062009
nucleic acid binding 3.39650042677839 bayes_pls_golite062009
transcription repressor activity 3.34221155527033 bayes_pls_golite062009
transcription factor activity 2.77967244868934 bayes_pls_golite062009
binding 2.73171412378045 bayes_pls_golite062009
protein binding 2.43603601331034 bayes_pls_golite062009
gated channel activity 2.31670938272069 bayes_pls_golite062009
cation channel activity 2.29487032939987 bayes_pls_golite062009
ion channel activity 2.26817638058015 bayes_pls_golite062009
potassium channel activity 1.44385468589872 bayes_pls_golite062009
voltage-gated cation channel activity 1.43775565332764 bayes_pls_golite062009
substrate-specific transporter activity 1.43014386864286 bayes_pls_golite062009
channel activity 1.41924822300643 bayes_pls_golite062009
passive transmembrane transporter activity 1.41924822300643 bayes_pls_golite062009
voltage-gated ion channel activity 1.41843723045096 bayes_pls_golite062009
substrate-specific channel activity 1.4152854884651 bayes_pls_golite062009
voltage-gated channel activity 1.40892835925684 bayes_pls_golite062009
sequence-specific DNA binding 1.3794923488776 bayes_pls_golite062009
voltage-gated potassium channel activity 1.37848954483947 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.36107960937272 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.34347609298791 bayes_pls_golite062009
ion transmembrane transporter activity 1.32720756453806 bayes_pls_golite062009
transcription activator activity 1.3134483946218 bayes_pls_golite062009
cation transmembrane transporter activity 1.2813343017365 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.933012980583336 bayes_pls_golite062009
specific transcriptional repressor activity 0.69971422997918 bayes_pls_golite062009
transporter activity 0.14391700968389 bayes_pls_golite062009
catalytic activity 0.112500532859479 bayes_pls_golite062009
chromatin binding 0.0908724449159477 bayes_pls_golite062009
transmembrane transporter activity 0.0733959562343498 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [134-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GATGSESTAT TPQLQRIQPY LVPQRNRSQA GGLLASAANA GNTPTLPVQP SLLSSALMPK  60
   61 RKRGRPRKLS GSSNGTGNDY DDFDRENMMN DSSDLGNGKM CNESYSGNDD GSDDNQPNAG 120
  121 HTDDLNESRD SLPSKRSKNS KDHRVVSHHE DNSTSVTPTK ATPEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [299-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQRLFGSSST TISATAPGGS STGPSETISL LEISDERESA PVHLPTILGL KIRAINTTTP  60
   61 AQQGSPQTPT KSKPKIRQAT GSNNSNSLLK QQLR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [393-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGAKDPEVPP ATRITGAVTP NAALNAEEQS KEMPKKNQDE VNACIGLHSL ANAAEQQAAQ  60
   61 VASTGNLHHQ LLLHMAANNS MLNTTDYYQQ QQQESPSSAG QFMDDDLELL SLNDQQDKSD 120
  121 EPDHEMVTLA DENAGLPGYQ GNEAEATPAQ EDSPAAETAT APPPAPRSGK KGAKRPIQRR 180
  181 RVRRKAQSTL DDQAEHLTEM SVRGLDLFRY ASVVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.0
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #5
Region A:
Residues: [608-813]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVYRCTECAK ENMQKTFKNK YSFQRHAFLY HEGKHRKVFP CPVCSKEFSR PDKMKNHLKM  60
   61 THENFTPPKD IGAFSPLKYL ISAAAAGDMH ATIYQQQQDH YHRQLAEQLE QQNASFDSRD 120
  121 SSLILPDVKM EHAEDQDAEQ EAELSDGGYD ASNPAAAAAA MLSLQQDVII KDEIQISPSP 180
  181 SPTPPASCAV AEGKSLALAS TAQTAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.69897
Match: 2gliA
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription activator activity 3.52873291636993 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
transcription repressor activity 3.27542149084008 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
sequence-specific DNA binding 2.53101891154822 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
protein binding 2.05530362750351 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
transcription corepressor activity 1.34049786451995 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle