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View Structure Prediction Details

Protein: tst-PA, FBpp0306916
Organism: Drosophila melanogaster
Length: 1197 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tst-PA, FBpp0306916.

Description E-value Query
Range
Subject
Range
gi|13446608 - gi|13446608|emb|CAC35050.1| putative helicase Ski2 [Drosophila melanogaster]
831.0 [0..1] [1197..1]

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Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEIRGEDNL ERLRNYILRP ELSLHNPLPD VLPRKFDPMR LLHAPRCPGS TKLAPRRDQS  60
   61 GHILEFVELD LEAVGANANN SMSMQREPGL LEDATRGSHS NFPFWPGGFD EQRQQIAALD 120
  121 VSNFQFGDKL LTVPPGFSSG YDFFQSQSVT LPPVVADPSN VDLLENLEQD LDVQEWMKLT 180
  181 RSEETSSTGT PKSPKQSNVQ LPSEEFRDVD DHIMKADLKP VLNISTTTKN FKSDWAEMVD 240
  241 I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [242-796]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQPINNFKEQ IPCPAMDFPF ELDVFQKQAI LKLEQRQYVF VAAHTSAGKT VVAEYAIALS  60
   61 KRDLTRTIYT SPIKALSNQK YRDFRKTFKD VGLITGDLQI EPTASCLIMT TEILRSMLYC 120
  121 GSDVTRDLEW VIFDEVHYIN NPERGHVWEE VIILLPEHVN IIMLSATVPN TLELADWVGS 180
  181 TKKRKVYVIS TLKRPVPLTH FLYTGAGGKS RDDIFLLVDA QGKYLQGNYE KAVERKKEMQ 240
  241 GKAKGGGGGP RNHLNAKQEQ YTWIGLIDFL RRSNMMPVVA FTLSRNRCDS NLAALQSVDL 300
  301 NTEKEKGAVQ KFFLQCLAKL KPPDRTIPQV LVLKDALERG IGVHHSGILP ILKEIVEMLF 360
  361 QNGLVKLLFA TETFAMGVNM PARTVVFDSC KKFDGLEMRN LKPGEYIQMA GRAGRRGHDE 420
  421 TGTAIIMCKG SVPPSMELRP MILGLPEKLQ SQFILRYAVI LTCLRIESIK VEDIMKFSFK 480
  481 EFNLKLQLPT QQKQLRLAED KFAMLPTLGE HLQPLVNFYD KAVEYWKEKH RIMKFVVTQP 540
  541 KIQKELKAGR VIVIT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.09691
Match: 2p6rA
Description: No description for 2p6rA was found.

Predicted functions:

Term Confidence Notes
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
transporter activity 2.58140740499725 bayes_pls_golite062009
hydrolase activity 2.55157966585974 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
transmembrane transporter activity 2.39695871109024 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
ATPase activity, coupled 2.18396165590908 bayes_pls_golite062009
DNA binding 1.94055378599526 bayes_pls_golite062009
transcription regulator activity 1.83584389083042 bayes_pls_golite062009
1.75135117904448 bayes_pls_golite062009
structural constituent of ribosome 1.47858140861683 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
motor activity 1.34881124154297 bayes_pls_golite062009
substrate-specific transporter activity 1.29730375126024 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription factor activity 0.959949409533517 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.906554174337376 bayes_pls_golite062009
structural molecule activity 0.86514677273731 bayes_pls_golite062009
RNA binding 0.715902454627085 bayes_pls_golite062009
ribonuclease activity 0.712344060953362 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
ligase activity 0.417681194526243 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
ion transmembrane transporter activity 0.355466224802969 bayes_pls_golite062009
microtubule motor activity 0.32730260506261 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
guanyl nucleotide binding 0.296406132096546 bayes_pls_golite062009
GTP binding 0.295705904888768 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
guanyl ribonucleotide binding 0.29028316917561 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
microfilament motor activity 0.10236059675512 bayes_pls_golite062009
protein transporter activity 0.0397092337273124 bayes_pls_golite062009
cation transmembrane transporter activity 0.0254369227200564 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [797-969]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGKHYNKLAI LLNTKSVPGK DTIYKVLVLD HQFKAKDSNS LQQGELYYKI LSLTPRNMTF  60
   61 QPVGIGGHTV LDIKAIDIIS ITKSTLKVDA DAIIRNWEQR QLERFKDSPP SGSVVKAVTE 120
  121 LNQLNESYID NPDNIKYVNL SKEIIVNADS EVAMLNYVDH LLRKVGEFLP HTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [970-1080]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAGFEQEFAK VYERRMLEIH IEELRFKNSA RNLTLYPDYC NKLKVLRALK YIDELDEVTL  60
   61 KGKVACEMGQ NELLITELIL CNMFNDLEPA EIAALLSGLV FQAKMQDKPV I

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1081-1197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEALKECVAA FEQINDTILA EEQRFQAAIE TDNRLNFGLL EVVYEWARNK PFAEIMKLTT  60
   61 VQEGIIVRCI QQLNETLRDV KTAAIRIGNP GLQSKMEEAS AAIKRDIVFT ASLYTEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle