| Protein: | aux-PA, aux-PB |
| Organism: | Drosophila melanogaster |
| Length: | 1165 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aux-PA, aux-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
753.0 | [0..1] | [1165..1] |
|
Region A: Residues: [1-388] |
1 11 21 31 41 51
| | | | | |
1 MGEFFKSLNL NYFSSSEVNG AAGNGAPEAL GGRLDNDFVG QVVEVAGHRL RIKCVIAEGG 60
61 YAFVYVAQDV QTGTEYALKR LIGADMQAST AIINEINIHK QLSGHENIVA FVGSSYTAPS 120
121 TQLGAQYLLL TELCKGGSLV DCFRTNNAPF NPTCVLRIFY QMARAVASLH SQSPPIAHRD 180
181 IKIENFLIGN DKQIKLCDFG SASTEVLSPT FEWSANQRSM LEDQLNTVTT PMYRSPEMLD 240
241 TWSNNPIGPK VDIWALGCIL YFLCYRKHPY EDGGKLRIIN ANYMLPPDPQ YQCFSDIIRG 300
301 CLKVNPFERL DITMVLEGLA ALAETHNWSL KGPLDLHIMP IESLPAESPL KSSAYSEVYT 360
361 EPLSAAIPSS YNGHGSLLSS LRGGAGTL
|
| Detection Method: |  |
| Confidence: | 83.154902 |
| Match: | 1xjdA |
| Description: | Crystal Structure of PKC-theta complexed with Staurosporine at 2A resolution |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| nucleic acid binding | 1.46547714006072 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.913893847407112 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.821371946077904 | bayes_pls_golite062009 |
| receptor activity | 0.775180603313375 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.461392047923247 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.401250804041384 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| signal transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| molecular transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| MAP kinase activity | 0.26024936404169 | bayes_pls_golite062009 |
|
Region A: Residues: [389-694] |
1 11 21 31 41 51
| | | | | |
1 LKNIKDTSTK VMQTMQQSLA RNDLDISHIT SRILVMPCPS DGFESTYKTN NIEDVRLSLE 60
61 SRFVPQKLSI YNFGQRTEPR LPPPVRTVEA GSVYGCPQAH APNLQGLFTV SADMYNFLNA 120
121 DPKSVVIVQT GDSGGCTAAT VICALLMYAD LLREPEDAVQ VFAVKRHTIN LRPSEFRYLY 180
181 YFGDILRPTP LLPHYKNTTL VSLSCQPVPR MTKARDGCRI YMEVYCNGNL LLSTLQDYEK 240
241 MRLYQAGPGK IVLPINLTAC GDVTVVLFHA RKGMVRPQGL KICQFQFNTG FIPEPETLIT 300
301 FTNQDL
|
| Detection Method: | |
| Confidence: | 76.69897 |
| Match: | 1d5rA |
| Description: | Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain; Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphatase activity | 3.46044873655892 | bayes_pls_golite062009 |
| phosphoprotein phosphatase activity | 3.31810516049102 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 3.27287246441913 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 2.72498052648516 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.31514936029825 | bayes_pls_golite062009 |
| protein binding | 2.12487185456363 | bayes_pls_golite062009 |
| binding | 2.06015698112379 | bayes_pls_golite062009 |
| nucleic acid binding | 2.05424732017237 | bayes_pls_golite062009 |
| DNA binding | 1.95001230878269 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.56455764981613 | bayes_pls_golite062009 |
| hydrolase activity | 1.5596484415033 | bayes_pls_golite062009 |
| kinase activity | 1.54798529194457 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.36326098454926 | bayes_pls_golite062009 |
| protein kinase activity | 1.3466747511896 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.19889854601141 | bayes_pls_golite062009 |
| calcium-dependent phospholipid binding | 1.06635493706319 | bayes_pls_golite062009 |
| catalytic activity | 1.06283028154109 | bayes_pls_golite062009 |
| transferase activity | 1.05480035577492 | bayes_pls_golite062009 |
| receptor activity | 1.01393772058468 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine phosphatase activity | 0.743245088266464 | bayes_pls_golite062009 |
| transmembrane receptor protein phosphatase activity | 0.743245088266464 | bayes_pls_golite062009 |
| protein tyrosine/serine/threonine phosphatase activity | 0.631313032497835 | bayes_pls_golite062009 |
| SNARE binding | 0.501334097212321 | bayes_pls_golite062009 |
| neurexin binding | 0.27749877320051 | bayes_pls_golite062009 |
|
Region A: Residues: [695-1078] |
1 11 21 31 41 51
| | | | | |
1 DDLPDPEQVT PRFCVSLSLA VTDSESPPSH KPPWMPAKPK RSPAALFSSD LEYAEMLDNF 60
61 VTKPSTRSSP PPGARKSDRV SSPLVLPDVT ETAHELPSPM PEPSPPIDLL NLNQQPSDVP 120
121 AADPLTSAKP STDASFDLLG AFGDDDSTGI GSAPIPDILP PPPLQQPQPK INNDPFDIFG 180
181 SVDQGGVPSM KPSGFPPFVG SLPTFVAQPA ATTNPSPTHP ARASADPFAN IADLATGLNL 240
241 NFNRSTLSGK SPVNTSPQPT QFSSPTHKPS PSSQPQATFM HTPPTPQTLP STSSIRTPTQ 300
301 PQAVPAQSRP DYSRLHFDSQ KAAQQPGTGG SKNSDIFADI LGQQGYSFGS KMNQCPRSIN 360
361 EMRKEDLFKD MDPKKVRIME WTDG
|
| Detection Method: | |
| Confidence: | 6.69897 |
| Match: | 1y0fB |
| Description: | No description for 1y0fB was found. |
|
Region A: Residues: [1079-1165] |
1 11 21 31 41 51
| | | | | |
1 KKNNIRALLC SMHTVLWDNA KWQRCEMSTM VTPTEVKKAY RRACLAVHPD KHNGTENEEI 60
61 AKLIFMELNN AWTDFENDAT QQNMFNA
|
| Detection Method: | |
| Confidence: | 50.39794 |
| Match: | 1n4cA |
| Description: | NMR Structure of the J-Domain and Clathrin Substrate Binding Domain of Bovine Auxilin |
Matching Structure (courtesy of the PDB): |
|
