| Protein: | Pi3K59F-PA |
| Organism: | Drosophila melanogaster |
| Length: | 949 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pi3K59F-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
864.0 | [0..1] | [949..1] |
|
Region A: Residues: [1-153] |
1 11 21 31 41 51
| | | | | |
1 MDQPDDHFRY IHSSSLHERV QIKVGTLEGK KRQPDYEKLL EDPILRFSGL YSEEHPSFQV 60
61 RLQVFNQGRP YCLPVTSSYK AFGKRWSWNE WVTLPLQFSD LPRSAMLVLT ILDCSGAGQT 120
121 TVIGGTSISM FGKDGMFRQG MYDLRVWLGV EGD
|
| Detection Method: |  |
| Confidence: | 1.37 |
| Match: | 2uzpA |
| Description: | No description for 2uzpA was found. |
|
Region A: Residues: [154-250] |
1 11 21 31 41 51
| | | | | |
1 GNFPSRTPGK GKESSKSQMQ RLGKLAKKHR NGQVQKVDWL DRLTFREIEV INEREKRMSD 60
61 YMFLMIEFPA IVVDDMYNYA VVYFEPEGDV KYKLPAK
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [251-949] |
1 11 21 31 41 51
| | | | | |
1 PKLVSVPDSE IQMENLVERK HHRLARSERS GISDRDAKPT ASIRDQLHTI VYRYPPTYVL 60
61 SSEEQDLVWK FRFYLSSHKK ALTKFLKCIN WKLEDEVTQA LWMLANWAPM DVEDALELLS 120
121 PTFTHPQVRK YAVSRLAQAP DEDLLLYLLQ LVQALKYEDP RHIVHLHGCI FPERDVVRSI 180
181 LDDNGSLLDQ SSLSDLSATS SGLHGSVIPA NQRAASVLAA IKSDKSVSPG SAGGSGSGGQ 240
241 GSVALPNPSA PATPGSSSLP CDSNSNALML AEGISFGSVP ANLCTFLIQR ACTNATLANY 300
301 FYWYLSIEVE EVESVRKQDE RAHDMYAMVL KMFLKVLENG NFNLRGIFYN LRKQRRFIDE 360
361 LVKLVKLVAK EPGNRNKKTE KFQKLLAEQD MFKVNFTNFE PIPFPLDPEI YITKIVPMRT 420
421 SLFKSALMPA KLTFVTSIAH HEYAAIFKHG DDLRQDQLIL QMITLMDKLL RRENLDLKLT 480
481 PYKVLATSSK HGFLQYVDSC TVAEVLAREG NIHNFFRKHH PCDNGPYGIS AEVMDTYIKS 540
541 CAGYCVITYL LGVGDRHLDN LLLTTNGKLF HIDFGYILGR DPKPMPPPMK LSKEMVEAMG 600
601 GISSEHHHEF RKQCYTAYLH LRRHANVMLN LFSLMVDATV PDIALEPDKA VKKVEENLQL 660
661 GLTDEEAVQH LQSLLDVSIT AVMPALVEQI HRFTQYWRK
|
| Detection Method: | |
| Confidence: | 115.0 |
| Match: | 1e7uA |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 1-phosphatidylinositol-3-kinase activity | 8.12544462052019 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase activity | 8.10715314025226 | bayes_pls_golite062009 |
| lipid kinase activity | 5.98454599133418 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol kinase activity | 5.59422890717019 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| protein kinase activity | 5.17195961442593 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity | 4.51744163880238 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| binding | 2.31930216202447 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| molecular transducer activity | 1.79921740914853 | bayes_pls_golite062009 |
| signal transducer activity | 1.79921740914853 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 1.02389895825558 | bayes_pls_golite062009 |
| profilin binding | 0.982035967740892 | bayes_pls_golite062009 |
| phospholipase activity | 0.689713182053935 | bayes_pls_golite062009 |
| transporter activity | 0.595111702412257 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.58590430118616 | bayes_pls_golite062009 |
| MAP kinase activity | 0.5066845540941 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.41384976209545 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| signal sequence binding | 0.14931345687137 | bayes_pls_golite062009 |
| phospholipase C activity | 0.105085008317406 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.0922946791401962 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
