| Protein: | Dscam-PAM |
| Organism: | Drosophila melanogaster |
| Length: | 2017 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PAM.
| Description | E-value | Query Range |
Subject Range |
|
|
1519.0 | [0..3] | [2017..3] |
|
Region A: Residues: [1-138] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVN
|
| Detection Method: |  |
| Confidence: | 81.0 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [139-810] |
1 11 21 31 41 51
| | | | | |
1 QFYEAEIMTE YVIRGNAAVL KCSIPSFVAD FVRVESWIDD EGNVLSFSDN YDGKYLVLPS 60
61 GELHIREVGP EDGYKSYQCR TKHRLTGETR LSATKGRLVI TEPVGSVAPK VDMQDKFGVN 120
121 IRQANNSLNL LCKAQGYPMP AFRWYKFIEG TTRKQAVVLN DRVKQVSGTL IIKDAVVEDS 180
181 GKYLCVVNNS VGGESVETVL TVTAPLSAKI DPPTQTVDFG RPAVFTCQYT GNPIKTVSWM 240
241 KDGKAIGHSE PVLRIESVKK EDKGMYQCFV RNDQESAEAS AELKLGGRFD PPVIRQAFQE 300
301 ETMEPGPSVF LKCVAGGNPT PEISWELDGK KIANNDRYQV GQYVTVNGDV VSYLNITSVH 360
361 ANDGGLYKCI AKSKVGVAEH SAKLNVYGLP YIRQMEKKAI VAGETLIVTC PVAGYPIDSI 420
421 VWERDNRALP INRKQKVFPN GTLIIENVER NSDQATYTCV AKNQEGYSAR GSLEVQVMVP 480
481 PQVLPFSFGE SAADVGDIAS ANCVVPKGDL PLEIRWSLNS APIVNGENGF TLVRLNKRTS 540
541 LLNIDSLNAF HRGVYKCIAT NPAGTSEYVA ELQVNVPPRW ILEPTDKAFA QGSDAKVECK 600
601 ADGFPKPQVT WKKAVGDTPG EYKDLKKSDN IRVEEGTLHV DNIQKTNEGY YLCEAINGIG 660
661 SGLSAVIMIS VQ
|
| Detection Method: | |
| Confidence: | 58.0 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [811-950] |
1 11 21 31 41 51
| | | | | |
1 APPEFTEKLR NQTARRGEPA VLQCEAKGEK PIGILWNMNN MRLDPKNDNR YTIREEILST 60
61 GVMSSLSIKR TERSDSALFT CVATNAFGSD DASINMIVQE VPEMPYALKV LDKSGRSVQL 120
121 SWAQPYDGNS PLDRYIIEFK
|
| Detection Method: | |
| Confidence: | 33.522879 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [951-1114] |
1 11 21 31 41 51
| | | | | |
1 RSRASWSEID RVIVPGHTTE AQVQKLSPAT TYNIRIVAEN AIGTSQSSEA VTIITAEEAP 60
61 SGKPQNIKVE PVNQTTMRVT WKPPPRTEWN GEILGYYVGY KLSNTNSSYV FETINFITEE 120
121 GKEHNLELQN LRVYTQYSVV IQAFNKIGAG PLSEEEKQFT AEGT
|
| Detection Method: | |
| Confidence: | 16.522879 |
| Match: | 2dtgE |
| Description: | No description for 2dtgE was found. |
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 3.5949595622742 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| interleukin-2 binding | 2.38131482184802 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.9781930293417 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.9781930293417 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| mercury ion binding | 1.85843060232985 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| cytokine receptor binding | 1.37111932405391 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| growth hormone receptor activity | 1.15929762138929 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| cytokine activity | 1.09433218752101 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.992216255634359 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.817385502041609 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.721156833238761 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.721156833238761 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
| growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| cell surface binding | 0.366415248711076 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor binding | 0.338520586013721 | bayes_pls_golite062009 |
| pattern binding | 0.31156427047296 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
|
Region A: Residues: [1115-1485] |
1 11 21 31 41 51
| | | | | |
1 PSQPPSDTAC TTLTSQTIRV GWVSPPLESA NGVIKTYKVV YAPSDEWYDE TKRHYKKTAS 60
61 SDTVLHGLKK YTNYTMQVLA TTAGGDGVRS VPIHCQTEPD VPEAPTDVKA LVMGNAAILV 120
121 SWRPPAQPNG IITQYTVYSK AEGAETETKT QKVPHYQMSF EATELEKNKP YEFWVTASTT 180
181 IGEGQQSKSI VAMPSDQVPA KIASFDDTFT ATFKEDAKMP CLAVGAPQPE ITWKIKGVEF 240
241 SANDRMRVLP DGSLLIKSVN RQDAGDYSCH AENSIAKDSI THKLIVLAPP QSPHVTLSAT 300
301 TTDALTVKLK PHEGDTAPLH GYTLHYKPEF GEWETSEVSV DSQKHNIEGL LCGSRYQVYA 360
361 TGFNNIGAGE A
|
| Detection Method: | |
| Confidence: | 13.221849 |
| Match: | 1zlgA |
| Description: | No description for 1zlgA was found. |
|
Region A: Residues: [1486-1602] |
1 11 21 31 41 51
| | | | | |
1 SDILNTRTKG QKPKLPEKPR FIEVSSNSVS LHFKAWKDGG CPMSHFVVES KKRDQIEWNQ 60
61 ISNNVKPDNN YVVLDLEPAT WYNLRITAHN SAGFTVAEYD FATLTVTGGT IAPSRDL
|
| Detection Method: | |
| Confidence: | 27.30103 |
| Match: | 1fnfA |
| Description: | FRAGMENT OF HUMAN FIBRONECTIN ENCOMPASSING TYPE-III REPEATS 7 THROUGH 10 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1603-1785] |
1 11 21 31 41 51
| | | | | |
1 PELSAEDTIR IILSNLNLVV PVVAALLVII IAIIVICILR SKGNHHKDDV VYNQTMGPGA 60
61 TLDKRRPDLR DELGYIAPPN RKLPPVPGSN YNTCDRIKRG RGGLRSNHST WDPRRNPNLY 120
121 EELKAPPVPM HGNHYGHAHG NAECHYRHPG MEDEICPYAT FHLLGFREEM DPTKAMNFQT 180
181 FPH
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1786-1905] |
1 11 21 31 41 51
| | | | | |
1 QNGHAGPVPG HAGTMLPPGH PGHVHSRSGS QSMPRANRYQ RKNSQGGQSS IYTPAPEYDD 60
61 PANCAEEDQY RRYTRVNSQG GSLYSGPGPE YDDPANCAPE EDQYGSQYGG PYGQPYDHYG 120
121
|
| Detection Method: | |
| Confidence: | 11.69897 |
| Match: | 1bpvA |
| Description: | TITIN MODULE A71 FROM HUMAN CARDIAC MUSCLE, NMR, 50 STRUCTURES |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 3.5949595622742 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| interleukin-2 binding | 2.38131482184802 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.9781930293417 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.9781930293417 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| mercury ion binding | 1.85843060232985 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| cytokine receptor binding | 1.37111932405391 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| growth hormone receptor activity | 1.15929762138929 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| cytokine activity | 1.09433218752101 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.992216255634359 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.817385502041609 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.721156833238761 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.721156833238761 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
| growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| cell surface binding | 0.366415248711076 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor binding | 0.338520586013721 | bayes_pls_golite062009 |
| pattern binding | 0.31156427047296 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
|
Region A: Residues: [1906-2017] |
1 11 21 31 41 51
| | | | | |
1 SRGSMGRRSI GSARNPGNGS PEPPPPPPRN HDMSNSSFND SKESNEISEA ECDRDHGPRG 60
61 NYGAVKRSPQ PKDQRTTEEM RKLIERNETG PKQLQLQQAN GAGFTAYDTM AV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
