| Protein: | Dscam-PAY |
| Organism: | Drosophila melanogaster |
| Length: | 2018 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PAY.
| Description | E-value | Query Range |
Subject Range |
|
|
1539.0 | [0..3] | [2018..3] |
|
Region A: Residues: [1-161] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVHQF YQTRVIDEFV LRGNSATLKC L
|
| Detection Method: |  |
| Confidence: | 78.69897 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [162-294] |
1 11 21 31 41 51
| | | | | |
1 VPSFVADFID VEGWIDEEGV EILRPLPDDS VDGKYLVLPS GELHIREVGP EDGYKSYQCR 60
61 TKHRLTGETR LSATKGRLVI TEPIGSVAPT ISGDRLQEQT RKLGHSFSIL CQGQAYPHPV 120
121 FRWYKFIEGT TRK
|
| Detection Method: | |
| Confidence: | 4.30103 |
| Match: | 1lo4H |
| Description: | Immunoglobulin heavy chain variable domain, VH; Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 6.64811984458494 | bayes_pls_golite062009 |
| alpha-actinin binding | 5.77350124471385 | bayes_pls_golite062009 |
| actinin binding | 5.69539760434923 | bayes_pls_golite062009 |
| structural constituent of muscle | 4.93896503565413 | bayes_pls_golite062009 |
| olfactory receptor activity | 4.21057154107121 | bayes_pls_golite062009 |
| receptor activity | 4.00123250685257 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.81769911097805 | bayes_pls_golite062009 |
| binding | 3.17641566810715 | bayes_pls_golite062009 |
| molecular transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
| signal transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
| peptide antigen binding | 2.94721224577771 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 2.83860944503193 | bayes_pls_golite062009 |
| growth factor binding | 2.28613301180608 | bayes_pls_golite062009 |
| protein binding | 2.22855404705168 | bayes_pls_golite062009 |
| IgG binding | 1.92633562075074 | bayes_pls_golite062009 |
| antigen binding | 1.63189745559168 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.58610597245454 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 1.52958974617075 | bayes_pls_golite062009 |
| actin binding | 1.42681407553255 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 1.36789541796983 | bayes_pls_golite062009 |
| protein kinase activity | 1.36635494500222 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32330470851159 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 1.30657787244536 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 1.27793818082552 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 1.24730237107473 | bayes_pls_golite062009 |
| DNA binding | 1.19412627500732 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.17845072849922 | bayes_pls_golite062009 |
| transcription regulator activity | 1.16252234499274 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.02428106476324 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.02286631988334 | bayes_pls_golite062009 |
| kinase activity | 0.929878054374821 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.878595022643164 | bayes_pls_golite062009 |
| protein complex binding | 0.83543827718565 | bayes_pls_golite062009 |
| actin filament binding | 0.760856470721016 | bayes_pls_golite062009 |
| collagen binding | 0.729893120256353 | bayes_pls_golite062009 |
| peptide binding | 0.729048089532569 | bayes_pls_golite062009 |
| receptor binding | 0.632627479346393 | bayes_pls_golite062009 |
| cytokine binding | 0.631436442105379 | bayes_pls_golite062009 |
| titin binding | 0.599892148302011 | bayes_pls_golite062009 |
| integrin binding | 0.599569390248921 | bayes_pls_golite062009 |
| structural molecule activity | 0.567620977360967 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.564762108830441 | bayes_pls_golite062009 |
| transcription factor activity | 0.54549168007511 | bayes_pls_golite062009 |
| myosin heavy chain binding | 0.49788128784685 | bayes_pls_golite062009 |
| cytokine receptor activity | 0.34165331857492 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.318890055375093 | bayes_pls_golite062009 |
| cell surface binding | 0.213817211551667 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.0579247757286607 | bayes_pls_golite062009 |
| transferase activity | 0.053007146193305 | bayes_pls_golite062009 |
|
Region A: Residues: [295-345] |
1 11 21 31 41 51
| | | | | |
1 QAVVLNDRVK QVSGTLIIKD AVVEDSGKYL CVVNNSVGGE SVETVLTVTA P
|
| Detection Method: | |
| Confidence: | 17.0 |
| Match: | 1fhgA |
| Description: | Telokin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [346-424] |
1 11 21 31 41 51
| | | | | |
1 LSAKIDPPTQ TVDFGRPAVF TCQYTGNPIK TVSWMKDGKA IGHSEPVLRI ESVKKEDKGM 60
61 YQCFVRNDQE SAEASAELK
|
| Detection Method: | |
| Confidence: | 4.64 |
| Match: | 1u2hA |
| Description: | X-ray Structure of the N-terminally truncated human APEP-1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [425-532] |
1 11 21 31 41 51
| | | | | |
1 LGGRFDPPVI RQAFQEETME PGPSVFLKCV AGGNPTPEIS WELDGKKIAN NDRYQVGQYV 60
61 TVNGDVVSYL NITSVHANDG GLYKCIAKSK VGVAEHSAKL NVYGLPYI
|
| Detection Method: | |
| Confidence: | 34.69897 |
| Match: | 2v9qA |
| Description: | No description for 2v9qA was found. |
|
Region A: Residues: [533-666] |
1 11 21 31 41 51
| | | | | |
1 RQMEKKAIVA GETLIVTCPV AGYPIDSIVW ERDNRALPIN RKQKVFPNGT LIIENVERNS 60
61 DQATYTCVAK NQEGYSARGS LEVQVMVPPK ITPFDFGAEP TNVEDSVSVT CLISSGDLPI 120
121 DIEWFFNDYG ISSY
|
| Detection Method: | |
| Confidence: | 34.69897 |
| Match: | 1ry7B |
| Description: | Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [667-1159] |
1 11 21 31 41 51
| | | | | |
1 SGINVVKGGK RNSMLSIDNV QARHAGKYSC RAKNYAAAVN YSTELIVNVP PRWILEPTDK 60
61 AFAQGSDAKV ECKADGFPKP QVTWKKAVGD TPGEYKDLKK SDNIRVEEGT LHVDNIQKTN 120
121 EGYYLCEAIN GIGSGLSAVI MISVQAPPEF TEKLRNQTAR RGEPAVLQCE AKGEKPIGIL 180
181 WNMNNMRLDP KNDNRYTIRE EILSTGVMSS LSIKRTERSD SALFTCVATN AFGSDDASIN 240
241 MIVQEVPEMP YALKVLDKSG RSVQLSWAQP YDGNSPLDRY IIEFKRSRAS WSEIDRVIVP 300
301 GHTTEAQVQK LSPATTYNIR IVAENAIGTS QSSEAVTIIT AEEAPSGKPQ NIKVEPVNQT 360
361 TMRVTWKPPP RTEWNGEILG YYVGYKLSNT NSSYVFETIN FITEEGKEHN LELQNLRVYT 420
421 QYSVVIQAFN KIGAGPLSEE EKQFTAEGTP SQPPSDTACT TLTSQTIRVG WVSPPLESAN 480
481 GVIKTYKVVY APS
|
| Detection Method: | |
| Confidence: | 26.0 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [1160-1215] |
1 11 21 31 41 51
| | | | | |
1 DEWYDETKRH YKKTASSDTV LHGLKKYTNY TMQVLATTAG GDGVRSVPIH CQTEPD
|
| Detection Method: | |
| Confidence: | 11.522879 |
| Match: | 1x5hA |
| Description: | The solution structure of the third fibronectin type III domain of human Neogenin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1216-1311] |
1 11 21 31 41 51
| | | | | |
1 VPEAPTDVKA LVMGNAAILV SWRPPAQPNG IITQYTVYSK AEGAETETKT QKVPHYQMSF 60
61 EATELEKNKP YEFWVTASTT IGEGQQSKSI VAMPSD
|
| Detection Method: | |
| Confidence: | 33.0 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [1312-1604] |
1 11 21 31 41 51
| | | | | |
1 QVPAKIASFD DTFTATFKED AKMPCLAVGA PQPEITWKIK GVEFSANDRM RVLPDGSLLI 60
61 KSVNRQDAGD YSCHAENSIA KDSITHKLIV LAPPQSPHVT LSATTTDALT VKLKPHEGDT 120
121 APLHGYTLHY KPEFGEWETS EVSVDSQKHN IEGLLCGSRY QVYATGFNNI GAGEASDILN 180
181 TRTKGQKPKL PEKPRFIEVS SNSVSLHFKA WKDGGCPMSH FVVESKKRDQ IEWNQISNNV 240
241 KPDNNYVVLD LEPATWYNLR ITAHNSAGFT VAEYDFATLT VTGGTIAPSR DLP
|
| Detection Method: | |
| Confidence: | 23.0 |
| Match: | 1fnhA |
| Description: | Fibronectin, different Fn3 modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| receptor binding | 1.31676259534833 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| growth hormone receptor activity | 1.15929762138929 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.07748328484506 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.99058387466784 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 0.888638861691021 | bayes_pls_golite062009 |
| interleukin-6 binding | 0.888638861691021 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| cell surface binding | 0.792329562040096 | bayes_pls_golite062009 |
| heparin binding | 0.7054081997714 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| collagen binding | 0.688581536921572 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
| transferase activity | 0.432850266451294 | bayes_pls_golite062009 |
| polysaccharide binding | 0.4326581122899 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| pattern binding | 0.30071837231983 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
|
Region A: Residues: [1605-1684] |
1 11 21 31 41 51
| | | | | |
1 ELSAEDTIRI ILSNLNLVVP VVAALLVIII AIIVICILRS KGNHHKDDVV YNQTMGPGAT 60
61 LDKRRPDLRD ELGYIAPPNR
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1685-1921] |
1 11 21 31 41 51
| | | | | |
1 KLPPVPGSNY NTCDRIKRGR GGLRSNHSTW DPRRNPNLYE ELKAPPVPMH GNHYGHAHGN 60
61 AECHYRHPGM EDEICPYATF HLLGFREEMD PTKAMNFQTF PHQNGHAGPV PGHAGTMLPP 120
121 GHPGHVHSRS GSQSMPRANR YQRKNSQGGQ SSIYTPAPEY DDPANCAEED QYRRYTRVNS 180
181 QGGSLYSGPG PEYDDPANCA PEEDQYGSQY GGPYGQPYDH YGSRGSMGRR SIGSARN
|
| Detection Method: | |
| Confidence: | 20.69897 |
| Match: | 2nv5A |
| Description: | No description for 2nv5A was found. |
|
Region A: Residues: [1922-2018] |
1 11 21 31 41 51
| | | | | |
1 PGNGSPEPPP PPPRNHDMSN SSFNDSKESN EISEAECDRD HGPRGNYGAV KRSPQPKDQR 60
61 TTEEMRKLIE RNETGPKQLQ LQQANGAGFT AYDTMAV
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
