| Protein: | Dscam-PAW |
| Organism: | Drosophila melanogaster |
| Length: | 2034 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PAW.
| Description | E-value | Query Range |
Subject Range |
|
|
1486.0 | [0..3] | [2034..3] |
|
Region A: Residues: [1-246] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVHQF YQTRVIDEFV LRGNSATLKC LVPSFVADFI DVEGWIDEEG 180
181 VEILRPLPDD SVDGKYLVLP SGELHIREVG PEDGYKSYQC RTKHRLTGET RLSATKGRLV 240
241 ITEPIG
|
| Detection Method: |  |
| Confidence: | 76.154902 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [247-897] |
1 11 21 31 41 51
| | | | | |
1 SKAPSVPTGV MVFQQQVPLL STFAMLCQAQ AFPVPVFRWY KFIEGTTRKQ AVVLNDRVKQ 60
61 VSGTLIIKDA VVEDSGKYLC VVNNSVGGES VETVLTVTAP LSAKIDPPTQ TVDFGRPAVF 120
121 TCQYTGNPIK TVSWMKDGKA IGHSEPVLRI ESVKKEDKGM YQCFVRNDQE SAEASAELKL 180
181 GGRFDPPVIR QAFQEETMEP GPSVFLKCVA GGNPTPEISW ELDGKKIANN DRYQVGQYVT 240
241 VNGDVVSYLN ITSVHANDGG LYKCIAKSKV GVAEHSAKLN VYGLPYIRQM EKKAIVAGET 300
301 LIVTCPVAGY PIDSIVWERD NRALPINRKQ KVFPNGTLII ENVERNSDQA TYTCVAKNQE 360
361 GYSARGSLEV QVMVAPKIAS FDFGEEPLNY GEPASVQCTI LGGDLPMNVT WLLNNATIDS 420
421 FHDISFSRIG KRINVLSIES VSAHHAGFYS CHAQNKAGIT AHSARLIVNV PPRWILEPTD 480
481 KAFAQGSDAK VECKADGFPK PQVTWKKAVG DTPGEYKDLK KSDNIRVEEG TLHVDNIQKT 540
541 NEGYYLCEAI NGIGSGLSAV IMISVQAPPE FTEKLRNQTA RRGEPAVLQC EAKGEKPIGI 600
601 LWNMNNMRLD PKNDNRYTIR EEILSTGVMS SLSIKRTERS DSALFTCVAT N
|
| Detection Method: | |
| Confidence: | 56.0 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [898-999] |
1 11 21 31 41 51
| | | | | |
1 AFGSDDASIN MIVQEVPEMP YALKVLDKSG RSVQLSWAQP YDGNSPLDRY IIEFKRSRAS 60
61 WSEIDRVIVP GHTTEAQVQK LSPATTYNIR IVAENAIGTS QS
|
| Detection Method: | |
| Confidence: | 35.221849 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [1000-1105] |
1 11 21 31 41 51
| | | | | |
1 SEAVTIITAE EAPSGKPQNI KVEPVNQTTM RVTWKPPPRT EWNGEILGYY VGYKLSNTNS 60
61 SYVFETINFI TEEGKEHNLE LQNLRVYTQY SVVIQAFNKI GAGPLS
|
| Detection Method: | |
| Confidence: | 6.22 |
| Match: | 1uenA |
| Description: | Solution Structure of The Third Fibronectin III Domain of Human KIAA0343 Protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.64191752950322 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.48327952154215 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.5103765150253 | bayes_pls_golite062009 |
| actinin binding | 4.48149264004887 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.45867823077829 | bayes_pls_golite062009 |
| receptor activity | 4.37793227341148 | bayes_pls_golite062009 |
| ankyrin binding | 4.3701493214749 | bayes_pls_golite062009 |
| cytokine binding | 3.96036354316187 | bayes_pls_golite062009 |
| growth factor binding | 3.72927884588092 | bayes_pls_golite062009 |
| cytokine receptor activity | 3.56710042152924 | bayes_pls_golite062009 |
| molecular transducer activity | 3.48919490776358 | bayes_pls_golite062009 |
| signal transducer activity | 3.48919490776358 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 3.42134839153875 | bayes_pls_golite062009 |
| protein binding | 3.07386271831775 | bayes_pls_golite062009 |
| binding | 3.01297199434173 | bayes_pls_golite062009 |
| receptor binding | 2.24607683514744 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.10516556578644 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.79394027888496 | bayes_pls_golite062009 |
| peptide hormone binding | 1.75574680918945 | bayes_pls_golite062009 |
| axon guidance receptor activity | 1.63462880446774 | bayes_pls_golite062009 |
| mercury ion binding | 1.51606310151325 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.50469234952074 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.44108205374377 | bayes_pls_golite062009 |
| protein kinase activity | 1.43845497070856 | bayes_pls_golite062009 |
| nucleic acid binding | 1.33776468784285 | bayes_pls_golite062009 |
| transcription regulator activity | 1.33202923701908 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.31623717161573 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.23418025988474 | bayes_pls_golite062009 |
| actin binding | 1.2168514525128 | bayes_pls_golite062009 |
| DNA binding | 1.20974701505243 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.17433712680111 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.14375759905113 | bayes_pls_golite062009 |
| kinase activity | 1.1286195376114 | bayes_pls_golite062009 |
| heparin binding | 1.00503605071474 | bayes_pls_golite062009 |
| cytokine activity | 0.961912275787352 | bayes_pls_golite062009 |
| structural molecule activity | 0.891799491886048 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 0.799335410052588 | bayes_pls_golite062009 |
| peptide binding | 0.758731415132682 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.745160473538126 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.705756302293137 | bayes_pls_golite062009 |
| protein dimerization activity | 0.674567146312744 | bayes_pls_golite062009 |
| transcription factor activity | 0.565342916629949 | bayes_pls_golite062009 |
| kinase binding | 0.557489547407687 | bayes_pls_golite062009 |
| collagen binding | 0.552918322648406 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.541677628277769 | bayes_pls_golite062009 |
| enzyme binding | 0.473046788409936 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.452957099078474 | bayes_pls_golite062009 |
| interleukin-6 binding | 0.42567751386992 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 0.42567751386992 | bayes_pls_golite062009 |
| polysaccharide binding | 0.411488590314852 | bayes_pls_golite062009 |
| growth factor activity | 0.39892291470381 | bayes_pls_golite062009 |
| identical protein binding | 0.368517091723107 | bayes_pls_golite062009 |
| pattern binding | 0.326372030550655 | bayes_pls_golite062009 |
| protein kinase binding | 0.316279870541718 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.284349891897882 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.277412437701811 | bayes_pls_golite062009 |
| cell surface binding | 0.276299257835729 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.214351244071116 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.214351244071116 | bayes_pls_golite062009 |
| hormone binding | 0.19211161691603 | bayes_pls_golite062009 |
| actin filament binding | 0.121647948863501 | bayes_pls_golite062009 |
| transcription activator activity | 0.0790192907314051 | bayes_pls_golite062009 |
| transcription factor binding | 0.013959055851287 | bayes_pls_golite062009 |
| integrin binding | 0.013361887492048 | bayes_pls_golite062009 |
|
Region A: Residues: [1106-1217] |
1 11 21 31 41 51
| | | | | |
1 EEEKQFTAEG TPSQPPSDTA CTTLTSQTIR VGWVSPPLES ANGVIKTYKV VYAPSDEWYD 60
61 ETKRHYKKTA SSDTVLHGLK KYTNYTMQVL ATTAGGDGVR SVPIHCQTEP DV
|
| Detection Method: | |
| Confidence: | 19.69897 |
| Match: | 1qg3A |
| Description: | Integin beta-4 subunit |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1218-1726] |
1 11 21 31 41 51
| | | | | |
1 PEAPTDVKAL VMGNAAILVS WRPPAQPNGI ITQYTVYSKA EGAETETKTQ KVPHYQMSFE 60
61 ATELEKNKPY EFWVTASTTI GEGQQSKSIV AMPSDQVPAK IASFDDTFTA TFKEDAKMPC 120
121 LAVGAPQPEI TWKIKGVEFS ANDRMRVLPD GSLLIKSVNR QDAGDYSCHA ENSIAKDSIT 180
181 HKLIVLAPPQ SPHVTLSATT TDALTVKLKP HEGDTAPLHG YTLHYKPEFG EWETSEVSVD 240
241 SQKHNIEGLL CGSRYQVYAT GFNNIGAGEA SDILNTRTKG QKPKLPEKPR FIEVSSNSVS 300
301 LHFKAWKDGG CPMSHFVVES KKRDQIEWNQ ISNNVKPDNN YVVLDLEPAT WYNLRITAHN 360
361 SAGFTVAEYD FATLTVTGGT IAPLDDGSGH GNVHTRIRLP AWMPEWLDLN FMVPLIATVV 420
421 VVAVGICVVC VALSRRRADD MRGGQKDVYY DVVYNQTMGP GATLDKRRPD LRDELGYIAP 480
481 PNRKLPPVPG SNYNTCDRIK RGRGGLRSN
|
| Detection Method: | |
| Confidence: | 23.0 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [1727-1868] |
1 11 21 31 41 51
| | | | | |
1 HSTWDPRRNP NLYEELKAPP VPMHGNHYGH AHGNAECHYR HPGMEDEICP YATFHLLGFR 60
61 EEMDPTKAMN FQTFPHQNGH AGPVPGHAGT MLPPGHPGHV HSRSGSQSMP RANRYQRKNS 120
121 QGGQSSIYTP APEYDDPANC AE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1869-2034] |
1 11 21 31 41 51
| | | | | |
1 EDQYRRYTRV NSQGGSLYSG PGPEYDDPAN CAPEEDQYGS QYGGPYGQPY DHYGSRGSMG 60
61 RRSIGSARNP GNGSPEPPPP PPRNHDMSNS SFNDSKESNE ISEAECDRDH GPRGNYGAVK 120
121 RSPQPKDQRT TEEMRKLIER NETGPKQLQL QQANGAGFTA YDTMAV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
