| Protein: | MCM7 |
| Organism: | Homo sapiens |
| Length: | 719 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCM7.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..719] | [1..720] |
|
|
0.0 | [1..719] | [1..719] |
|
|
0.0 | [1..719] | [1..719] |
|
|
0.0 | [1..719] | [1..719] |
|
|
0.0 | [1..719] | [1..719] |
|
|
0.0 | [1..719] | [1..719] |
|
Region A: Residues: [1-172] |
1 11 21 31 41 51
| | | | | |
1 MALKDYALEK EKVKKFLQEF YQDDELGKKQ FKYGNQLVRL AHREQVALYV DLDDVAEDDP 60
61 ELVDSICENA RRYAKLFADA VQELLPQYKE REVVNKDVLD VYIEHRLMME QRSRDPGMVR 120
121 SPQNQYPAEL MRRFELYFQG PSSNKPRVIR EVRADSVGKL VTVRGIVTRV SE
|
| Detection Method: |  |
| Confidence: | 35.39794 |
| Match: | 1ltlA |
| Description: | DNA replication initiator (cdc21/cdc54) N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [173-590] |
1 11 21 31 41 51
| | | | | |
1 VKPKMVVATY TCDQCGAETY QPIQSPTFMP LIMCPSQECQ TNRSGGRLYL QTRGSRFIKF 60
61 QEMKMQEHSD QVPVGNIPRS ITVLVEGENT RIAQPGDHVS VTGIFLPILR TGFRQVVQGL 120
121 LSETYLEAHR IVKMNKSEDD ESGAGELTRE ELRQIAEEDF YEKLAASIAP EIYGHEDVKK 180
181 ALLLLLVGGV DQSPRGMKIR GNINICLMGD PGVAKSQLLS YIDRLAPRSQ YTTGRGSSGV 240
241 GLTAAVLRDS VSGELTLEGG ALVLADQGVC CIDEFDKMAE ADRTAIHEVM EQQTISIAKA 300
301 GILTTLNARC SILAAANPAY GRYNPRRSLE QNIQLPAALL SRFDLLWLIQ DRPDRDNDLR 360
361 LAQHITYVHQ HSRQPPSQFE PLDMKLMRRY IAMCREKQPM VPESLADYIT AAYVEMRR
|
| Detection Method: | |
| Confidence: | 33.69897 |
| Match: | 1ksfX |
| Description: | N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA clamp loader activity | 4.91429252297969 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 4.80695929076807 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.66107861968804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| telomeric DNA binding | 2.0142766759353 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| microtubule motor activity | 1.6537049553461 | bayes_pls_golite062009 |
| RNA helicase activity | 1.63960194106079 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.62491387774159 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 1.61735400124552 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 1.60404584546501 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.53142082854758 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.52938239070386 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.52887308780164 | bayes_pls_golite062009 |
| nucleotide binding | 1.52746968836881 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.47858140861683 | bayes_pls_golite062009 |
| ATP binding | 1.23942044024113 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.21044170258803 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.20315703345493 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.19481945569892 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| motor activity | 1.14667913749579 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.05408274676326 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| transcription activator activity | 0.889929694023098 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| structural molecule activity | 0.86514677273731 | bayes_pls_golite062009 |
| transcription repressor activity | 0.862685397469217 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 0.8469248456592 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 0.700780808446722 | bayes_pls_golite062009 |
| kinase activity | 0.641541011250583 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.584453361662212 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.543891899378373 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.500462538667228 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.406600732518248 | bayes_pls_golite062009 |
| protein kinase activity | 0.351308564667977 | bayes_pls_golite062009 |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| four-way junction helicase activity | 0.26252931460003 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.243902356228423 | bayes_pls_golite062009 |
| exodeoxyribonuclease V activity | 0.185603938981231 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.156278588350022 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| mismatched DNA binding | 0.13366911641814 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.0223627159838333 | bayes_pls_golite062009 |
| actin binding | 0.00482938540552702 | bayes_pls_golite062009 |
|
Region A: Residues: [591-719] |
1 11 21 31 41 51
| | | | | |
1 EAWASKDATY TSARTLLAIL RLSTALARLR MVDVVEKEDV NEAIRLMEMS KDSLLGDKGQ 60
61 TARTQRPADV IFATVRELVS GGRSVRFSEA EQRCVSRGFT PAQFQAALDE YEELNVWQVN 120
121 ASRTRITFV
|
| Detection Method: | |
| Confidence: | 47.69897 |
| Match: | 1ojlA |
| Description: | Crystal structure of a sigma54-activator suggests the mechanism for the conformational switch necessary for sigma54 binding |
Matching Structure (courtesy of the PDB): |
|
