| Protein: | MCM5 |
| Organism: | Homo sapiens |
| Length: | 734 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCM5.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..734] | [1..734] |
|
|
0.0 | [1..734] | [1..734] |
|
|
0.0 | [1..734] | [1..734] |
|
|
0.0 | [1..734] | [1..734] |
|
|
0.0 | [1..734] | [1..735] |
|
Region A: Residues: [1-103] |
1 11 21 31 41 51
| | | | | |
1 MSGFDDPGIF YSDSFGGDAQ ADEGQARKSQ LQRRFKEFLR QYRVGTDRTG FTFKYRDELK 60
61 RHYNLGEYWI EVEMEDLASF DEDLADYLYK QPAEHLQLLE EAA
|
| Detection Method: |  |
| Confidence: | 35.39794 |
| Match: | 1ltlA |
| Description: | DNA replication initiator (cdc21/cdc54) N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [104-600] |
1 11 21 31 41 51
| | | | | |
1 KEVADEVTRP RPSGEEVLQD IQVMLKSDAS PSSIRSLKSD MMSHLVKIPG IIIAASAVRA 60
61 KATRISIQCR SCRNTLTNIA MRPGLEGYAL PRKCNTDQAG RPKCPLDPYF IMPDKCKCVD 120
121 FQTLKLQELP DAVPHGEMPR HMQLYCDRYL CDKVVPGNRV TIMGIYSIKK FGLTTSRGRD 180
181 RVGVGIRSSY IRVLGIQVDT DGSGRSFAGA VSPQEEEEFR RLAALPNVYE VISKSIAPSI 240
241 FGGTDMKKAI ACLLFGGSRK RLPDGLTRRG DINLLMLGDP GTAKSQLLKF VEKCSPIGVY 300
301 TSGKGSSAAG LTASVMRDPS SRNFIMEGGA MVLADGGVVC IDEFDKMRED DRVAIHEAME 360
361 QQTISIAKAG ITTTLNSRCS VLAAANSVFG RWDETKGEDN IDFMPTILSR FDMIFIVKDE 420
421 HNEERDVMLA KHVITLHVSA LTQTQAVEGE IDLAKLKKFI AYCRVKCGPR LSAEAAEKLK 480
481 NRYIIMRSGA RQHERDS
|
| Detection Method: | |
| Confidence: | 40.69897 |
| Match: | 1ksfX |
| Description: | N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA clamp loader activity | 4.91429252297969 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 4.80695929076807 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.66107861968804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| telomeric DNA binding | 2.0142766759353 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| microtubule motor activity | 1.6537049553461 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.62491387774159 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.53142082854758 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.52938239070386 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.52887308780164 | bayes_pls_golite062009 |
| nucleotide binding | 1.52746968836881 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.47858140861683 | bayes_pls_golite062009 |
| ATP binding | 1.23942044024113 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.21044170258803 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.20315703345493 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.19481945569892 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| motor activity | 1.14667913749579 | bayes_pls_golite062009 |
| kinase activity | 1.11120928120082 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.05408274676326 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.908046791062776 | bayes_pls_golite062009 |
| transcription activator activity | 0.889929694023098 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| structural molecule activity | 0.86514677273731 | bayes_pls_golite062009 |
| transcription repressor activity | 0.862685397469217 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 0.8469248456592 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 0.700780808446722 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.543891899378373 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.500462538667228 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.421921195209539 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.406600732518248 | bayes_pls_golite062009 |
| protein kinase activity | 0.351308564667977 | bayes_pls_golite062009 |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| four-way junction helicase activity | 0.26252931460003 | bayes_pls_golite062009 |
| exodeoxyribonuclease V activity | 0.185603938981231 | bayes_pls_golite062009 |
| RNA helicase activity | 0.18426050934025 | bayes_pls_golite062009 |
| transferase activity | 0.175269600441384 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.156278588350022 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.14606996093053 | bayes_pls_golite062009 |
| mismatched DNA binding | 0.13366911641814 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.13050483816765 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.0223627159838333 | bayes_pls_golite062009 |
| actin binding | 0.00482938540552702 | bayes_pls_golite062009 |
|
Region A: Residues: [601-734] |
1 11 21 31 41 51
| | | | | |
1 DRRSSIPITV RQLEAIVRIA EALSKMKLQP FATEADVEEA LRLFQVSTLD AALSGTLSGV 60
61 EGFTSQEDQE MLSRIEKQLK RRFAIGSQVS EHSIIKDFTK QKYPEHAIHK VLQLMLRRGE 120
121 IQHRMQRKVL YRLK
|
| Detection Method: | |
| Confidence: | 35.69897 |
| Match: | 2ce7A |
| Description: | EDTA treated |
Matching Structure (courtesy of the PDB): |
|
