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View Structure Prediction Details

Protein: FCERA_MOUSE, FCE...
Organism: Mus musculus
Length: 250 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FCERA_MOUSE, FCE....

Description E-value Query
Range
Subject
Range
gi|50744908 - gi|50744908|ref|XP_419931.1| PREDICTED: similar to CG12002-PA [Gallus gallus]
189.0 [0..3] [247..220]
gi|28972103 - gi|28972103|dbj|BAC65505.1| mKIAA0230 protein [Mus musculus]
182.0 [0..3] [247..174]
gi|57230943, gi|... - gi|57230943|tpg|DAA05635.1| TPA_exp: peroxidasin [Xenopus tropicalis], gi|134085437|ref|NP_001076815...
182.0 [0..3] [247..214]
gi|76661898 - gi|76661898|ref|XP_593953.2| PREDICTED: similar to CG12002-PA, isoform A [Bos taurus]
180.0 [0..3] [247..218]
HGNC:14966|MIM:6... - homolog (Drosophila)
gi|168267182, gi... - gi|168267182|dbj|BAG09668.1| peroxidasin homolog [synthetic construct], gi|147897889|gb|AAI40296.1| ...
PXDN - peroxidasin homolog (Drosophila)
179.0 [0..4] [247..222]
gi|73999336 - gi|73999336|ref|XP_544073.2| PREDICTED: similar to CG12002-PA, isoform A [Canis familiaris]
179.0 [0..3] [247..37]

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Predicted Domain #1
Region A:
Residues: [1-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTGRSAQLC LALLFMSLDV ILTATEKSVL TLDPPWIRIF TGEKVTLSCY GNNHLQMNST  60
   61 TKWIHNGTVS EVNSSHLVIV SATVQDSGKY ICQKQGLFKS KPVYLNVTQD WLLLQTSADM 120
  121 ILVHGSFDIR CHGWKNWNVR KVIYYRNDHA FNYSYESPVS IREATLNDSG TYHCKGYLRQ 180
  181 VEYESDKFRI AVVKAYK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.522879
Match: 1f2qA
Description: IgE high affinity receptor alpha subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptide antigen binding 6.88465387482513 bayes_pls_golite062009
antigen binding 5.9176308851452 bayes_pls_golite062009
IgG binding 5.54284971652486 bayes_pls_golite062009
immunoglobulin receptor activity 5.14639405668399 bayes_pls_golite062009
IgG receptor activity 4.31132706608247 bayes_pls_golite062009
immunoglobulin binding 4.25751339132775 bayes_pls_golite062009
IgE receptor activity 4.06997198366234 bayes_pls_golite062009
IgE binding 4.06997198366234 bayes_pls_golite062009
receptor activity 4.00123250685257 bayes_pls_golite062009
transmembrane receptor activity 3.81769911097805 bayes_pls_golite062009
binding 3.17641566810715 bayes_pls_golite062009
signal transducer activity 3.10913345555941 bayes_pls_golite062009
molecular transducer activity 3.10913345555941 bayes_pls_golite062009
olfactory receptor activity 2.99663023419676 bayes_pls_golite062009
protein binding 2.22855404705168 bayes_pls_golite062009
fibroblast growth factor 1 binding 2.19552124689493 bayes_pls_golite062009
nucleic acid binding 1.73930160869963 bayes_pls_golite062009
transcription regulator activity 1.69371027304398 bayes_pls_golite062009
DNA binding 1.61538654384419 bayes_pls_golite062009
growth factor binding 1.60826091835429 bayes_pls_golite062009
high affinity IgE receptor activity 1.55195842406798 bayes_pls_golite062009
protein kinase activity 1.36635494500222 bayes_pls_golite062009
fibroblast growth factor binding 1.27793818082552 bayes_pls_golite062009
G-protein coupled receptor activity 1.02428106476324 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.02286631988334 bayes_pls_golite062009
transcription activator activity 0.935229148203189 bayes_pls_golite062009
kinase activity 0.929878054374821 bayes_pls_golite062009
transcription factor activity 0.91425111006527 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.878595022643164 bayes_pls_golite062009
protein complex binding 0.83543827718565 bayes_pls_golite062009
peptide binding 0.729048089532569 bayes_pls_golite062009
coreceptor activity 0.661209696849389 bayes_pls_golite062009
receptor binding 0.632627479346393 bayes_pls_golite062009
cytokine binding 0.631436442105379 bayes_pls_golite062009
protein serine/threonine kinase activity 0.564762108830441 bayes_pls_golite062009
cell surface binding 0.477483205369537 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.447829399094714 bayes_pls_golite062009
cytokine receptor activity 0.34165331857492 bayes_pls_golite062009
protein tyrosine kinase activity 0.318890055375093 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.28309679787333 bayes_pls_golite062009
MHC class II receptor activity 0.251167772391909 bayes_pls_golite062009
transferase activity 0.053007146193305 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [198-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CKYYWLQLIF PLLVAILFAV DTGLLLSTEE QFKSVLEIQK TGKYKKVETE LLT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1axtH
Description: Immunoglobulin heavy chain variable domain, VH; Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle