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View Structure Prediction Details

Protein: ELC1
Organism: Saccharomyces cerevisiae
Length: 99 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ELC1.

Description E-value Query
Range		 Subject
Range
gi|33357846 - gi|33357846|pdb|1P22|A Chain A, Structure Of A Beta-Trcp1-Skp1-Beta-Catenin Complex: Destruction Mot...
 6.0E-32 [6..99] [4..94]
gi|18958257 - gi|18958257|dbj|BAB85607.1| kinetochore protein [Brassica juncea]
 3.0E-31 [1..99] [1..110]
gi|26347143, gi|... - gi|31560543|ref|NP_035673.2| S-phase kinase-associated protein 1A [Mus musculus], gi|26347143|dbj|BA...
 9.0E-31 [4..99] [2..112]
SKP1A_ARATH - SKP1-like protein 1A OS=Arabidopsis thaliana GN=SKP1A PE=1 SV=1
 1.0E-30 [1..99] [1..110]
gi|29841010 - gi|29841010|gb|AAP06023.1| SJCHGC06138 protein [Schistosoma japonicum]
 1.0E-30 [6..99] [4..112]

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Predicted Domain #1
Region A:
Residues: [1-47] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQDFVTLVS KDDKEYEISR SAAMISPTLK AMIEGPFRES KGRIELK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 452.522879
Match: 1hv2A_
Description: Elongin C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription elongation regulator activity 7.53002625989446 bayes_pls_golite062009
ubiquitin-protein ligase activity 6.78934422958647 bayes_pls_golite062009
small conjugating protein ligase activity 6.52079977531395 bayes_pls_golite062009
acid-amino acid ligase activity 5.78412146341235 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 4.95822114853319 bayes_pls_golite062009
transcription regulator activity 4.03732153795237 bayes_pls_golite062009
DNA binding 3.26500171477452 bayes_pls_golite062009
binding 3.25487903155187 bayes_pls_golite062009
nucleic acid binding 2.97922606919142 bayes_pls_golite062009
transcription factor activity 2.57500386784378 bayes_pls_golite062009
ligase activity 1.75579073151181 bayes_pls_golite062009
transcription repressor activity 1.71028791830657 bayes_pls_golite062009
protein binding 1.59297029384664 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.933012980583336 bayes_pls_golite062009
structure-specific DNA binding 0.784594789263781 bayes_pls_golite062009
voltage-gated potassium channel activity 0.318894446962849 bayes_pls_golite062009
voltage-gated cation channel activity 0.292746639637876 bayes_pls_golite062009
potassium channel activity 0.288501096353748 bayes_pls_golite062009
sequence-specific DNA binding 0.189580737604762 bayes_pls_golite062009
voltage-gated channel activity 0.172889160336679 bayes_pls_golite062009
voltage-gated ion channel activity 0.16355432097396 bayes_pls_golite062009
cation channel activity 0.158179353838005 bayes_pls_golite062009
catalytic activity 0.112500532859479 bayes_pls_golite062009
gated channel activity 0.0585265912733182 bayes_pls_golite062009
double-stranded DNA binding 0.033499769837058 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [48-99] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QFDSHILEKA VEYLNYNLKY SGVSEDDDEI PEFEIPTEMS LELLLAADYL SI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 452.522879
Match: 1hv2A_
Description: Elongin C
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle