| Protein: | RAD5 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1169 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD5.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1169] | [1..1169] |
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0.0 | [85..1168] | [1..1028] |
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0.0 | [13..1026] | [1539..2495] |
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0.0 | [60..1169] | [108..1132] |
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0.0 | [60..1107] | [108..1070] |
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0.0 | [7..1027] | [32..1021] |
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0.0 | [136..1069] | [423..1254] |
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Region A: Residues: [1-378] |
1 11 21 31 41 51
| | | | | |
1 MSHIEQEERK RFFNDDLDTS ETSLNFKSEN KESFLFANSH NDDDDDVVVS VSDTTEGEGD 60
61 RSIVPVRREI EEEGQNQFIT ELLRIIPEMP KDLVMELNEK FGSQEEGLSL ALSHYFDHNS 120
121 GTSISKIPSS PNQLNTLSDT SNSTLSPSSF HPKRRRIYGF RNQTRLEDKV TWKRFIGALQ 180
181 VTGMATRPTV RPLKYGSQMK LKRSSEEISA TKVYDSRGRK KASMASLVRI FDIQYDREIG 240
241 RVSEDIAQIL YPLLSSHEIS FEVTLIFCDN KRLSIGDSFI LQLDCFLTSL IFEERNDGES 300
301 LMKRRRTEGG NKREKDNGNF GRTLTETDEE LESRSKRLAL LKLFDKLRLK PILDEQKALE 360
361 KHKIELNSDP EIIDLDND
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| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
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Region A: Residues: [379-476] |
1 11 21 31 41 51
| | | | | |
1 EICSNQVTEV HNNLRDTQHE EETMNLNQLK TFYKAAQSSE SLKSLPETEP SRDVFKLELR 60
61 NYQKQGLTWM LRREQEFAKA ASDGEASETG ANMINPLW
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| Detection Method: | |
| Confidence: | 11.29 |
| Match: | 1gm5A |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [477-819] |
1 11 21 31 41 51
| | | | | |
1 KQFKWPNDMS WAAQNLQQDH VNVEDGIFFY ANLHSGEFSL AKPILKTMIK GGILSDEMGL 60
61 GKTVAAYSLV LSCPHDSDVV DKKLFDIENT AVSDNLPSTW QDNKKPYASK TTLIVVPMSL 120
121 LTQWSNEFTK ANNSPDMYHE VYYGGNVSSL KTLLTKTKTP PTVVLTTYGI VQNEWTKHSK 180
181 GRMTDEDVNI SSGLFSVNFY RIIIDEGHNI RNRTTVTSKA VMALQGKCKW VLTGTPIINR 240
241 LDDLYSLVKF LELDPWRQIN YWKTFVSTPF ESKNYKQAFD VVNAILEPVL LRRTKQMKDK 300
301 DGKPLVELPP KEVVIKRLPF SKSQDLLYKF LLDKAEVSVK SGI
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| Detection Method: | |
| Confidence: | 11.29 |
| Match: | 1gm5A |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [820-921] |
1 11 21 31 41 51
| | | | | |
1 ARGDLLKKYS TILVHILRLR QVCCHPGLIG SQDENDEDLS KNNKLVTEQT VELDSLMRVV 60
61 SERFDNSFSK EELDAMIQRL KVKYPDNKSF QSLECSICTT EP
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.387 | 0.171 | nuclear chromatin | a.1.1 | Globin-like |
| View | Download | 0.509 | 0.057 | nuclear chromatin | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.444 | 0.025 | nuclear chromatin | a.24.3 | Cytochromes |
| View | Download | 0.352 | 0.007 | nuclear chromatin | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.631 | 0.004 | nuclear chromatin | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.323 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.298 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.295 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.278 | N/A | N/A | b.2.5 | p53-like transcription factors |
| View | Download | 0.256 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.255 | N/A | N/A | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.251 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.249 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.249 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.245 | N/A | N/A | a.185.1 | Gametocyte protein Pfg27 |
| View | Download | 0.244 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.239 | N/A | N/A | a.130.1 | Chorismate mutase II |
| View | Download | 0.223 | N/A | N/A | d.192.1 | YlxR-like |
| View | Download | 0.223 | N/A | N/A | a.96.1 | DNA-glycosylase |
| View | Download | 0.222 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.209 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.207 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.205 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.201 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| Term | Confidence | Notes |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| binding | 2.05253348982328 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 1.84050240798436 | bayes_pls_golite062009 |
| pyrophosphatase activity | 1.81138802583782 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 1.78927528875848 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 1.78903889318615 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| microtubule motor activity | 1.35938517416356 | bayes_pls_golite062009 |
| motor activity | 1.32129340699286 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 1.29640539057136 | bayes_pls_golite062009 |
| hydrolase activity | 1.29419296935491 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.2539059700735 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATPase activity | 1.18431260772292 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 1.17617511072239 | bayes_pls_golite062009 |
| DNA polymerase activity | 1.14104131900023 | bayes_pls_golite062009 |
| DNA clamp loader activity | 1.12431517057397 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.117585097627 | bayes_pls_golite062009 |
| nucleic acid binding | 1.08697924060619 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA binding | 0.702147676354075 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.568457189190858 | bayes_pls_golite062009 |
| mismatched DNA binding | 0.31144582840038 | bayes_pls_golite062009 |
| transcription regulator activity | 0.287777990975748 | bayes_pls_golite062009 |
| DNA strand annealing activity | 0.283577486331079 | bayes_pls_golite062009 |
| nucleotide binding | 0.114848452385726 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.10713474095071 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.0916519414118148 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.0915913646217636 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
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Region A: Residues: [922-975] |
1 11 21 31 41 51
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1 MDLDKALFTE CGHSFCEKCL FEYIEFQNSK NLGLKCPNCR NQIDACRLLA LVQT
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.458 | 0.972 | nuclear chromatin | a.4.1 | Homeodomain-like |
| View | Download | 0.744 | 0.972 | nuclear chromatin | d.68.3 | SirA-like |
| View | Download | 0.427 | 0.972 | nuclear chromatin | a.4.1 | Homeodomain-like |
| View | Download | 0.324 | 0.972 | nuclear chromatin | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.318 | 0.972 | nuclear chromatin | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.317 | 0.972 | nuclear chromatin | a.60.1 | SAM/Pointed domain |
| View | Download | 0.302 | 0.972 | nuclear chromatin | a.60.2 | RuvA domain 2-like |
| View | Download | 0.275 | 0.972 | nuclear chromatin | a.108.1 | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| View | Download | 0.258 | 0.972 | nuclear chromatin | a.60.2 | RuvA domain 2-like |
| View | Download | 0.258 | 0.972 | nuclear chromatin | a.4.1 | Homeodomain-like |
| View | Download | 0.253 | 0.972 | nuclear chromatin | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.245 | 0.972 | nuclear chromatin | a.60.4 | DNA repair protein Rad51, N-terminal domain |
| View | Download | 0.240 | 0.972 | nuclear chromatin | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.237 | 0.972 | nuclear chromatin | d.58.36 | Sulfite reductase, domains 1 and 3 |
| View | Download | 0.234 | 0.972 | nuclear chromatin | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.217 | 0.972 | nuclear chromatin | a.74.1 | Cyclin-like |
| View | Download | 0.201 | 0.972 | nuclear chromatin | a.60.12 | DNA polymerase beta-like, second domain |
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Region A: Residues: [976-1169] |
1 11 21 31 41 51
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1 NSNSKNLEFK PYSPASKSSK ITALLKELQL LQDSSAGEQV VIFSQFSTYL DILEKELTHT 60
61 FSKDVAKIYK FDGRLSLKER TSVLADFAVK DYSRQKILLL SLKAGGVGLN LTCASHAYMM 120
121 DPWWSPSMED QAIDRLHRIG QTNSVKVMRF IIQDSIEEKM LRIQEKKRTI GEAMDTDEDE 180
181 RRKRRIEEIQ MLFE
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| Detection Method: | |
| Confidence: | 2.522879 |
| Match: | 1d9xA_ |
| Description: | Nucleotide excision repair enzyme UvrB |
Matching Structure (courtesy of the PDB): |
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