YRC Public Data Repository - Protein Structure Prediction

Protein:	URA2
Organism:	Saccharomyces cerevisiae
Length:	2214 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for URA2.

Description	E-value	Query Range	Subject Range
CARB_BUCAI - Carbamoyl-phosphate synthase large chain OS=Buchnera aphidicola subsp. Acyrthosiphon pisum (strain A... gi\|25293875 - gi\|25293875\|pir\|\|F84946 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) large chai... CARB_BUCAI - Carbamoyl-phosphate synthase large chain OS=Buchnera aphidicola subsp. Acyrthosiphon pisum GN=carB P...	0.0	[433..1507]	[2..1074]
CE03105 - WBGene00004259 locus:pyr-1 glutamine-dependent carbamoyl-phosphate synthase, aspartate carbamoyltran...	0.0	[20..2211]	[1..2194]
gi\|124122439, gi... - gi\|153802029\|ref\|ZP_01956615.1\| carbamoyl-phosphate synthase, large subunit [Vibrio cholerae MZO-3],... gi\|126519143, gi... - gi\|229512256\|ref\|ZP_04401735.1\| carbamoyl-phosphate synthase large chain [Vibrio cholerae B33], gi\|2... gi\|125617231, gi... - gi\|75828898\|ref\|ZP_00758228.1\| COG0458: Carbamoylphosphate synthase large subunit (split gene in MJ)... gi\|147673654, gi... - gi\|75827657\|ref\|ZP_00757092.1\| COG0458: Carbamoylphosphate synthase large subunit (split gene in MJ)... CARB_VIBCH - Carbamoyl-phosphate synthase large chain OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor ... gi\|153828839, gi... - gi\|153828839\|ref\|ZP_01981506.1\| carbamoyl-phosphate synthase, large subunit [Vibrio cholerae 623-39]... gi\|229607054, gi... - gi\|229607054\|ref\|YP_002877702.1\| carbamoyl-phosphate synthase large chain [Vibrio cholerae MJ-1236],... gi\|229528623, gi... - gi\|229528623\|ref\|ZP_04418013.1\| carbamoyl-phosphate synthase large chain [Vibrio cholerae 12129(1)],... gi\|229521221, gi... - gi\|229521221\|ref\|ZP_04410641.1\| carbamoyl-phosphate synthase large chain [Vibrio cholerae TM 11079-8... gi\|229344081, gi... - gi\|229519392\|ref\|ZP_04408835.1\| carbamoyl-phosphate synthase large chain [Vibrio cholerae RC9], gi\|2... gi\|229507548, gi... - gi\|229507548\|ref\|ZP_04397053.1\| carbamoyl-phosphate synthase large chain [Vibrio cholerae BX 330286]... gi\|227082512, gi... - gi\|227082512\|ref\|YP_002811063.1\| carbamoyl-phosphate synthase, large subunit [Vibrio cholerae M66-2]... gi\|121591079, gi... - gi\|121591079\|ref\|ZP_01678391.1\| carbamoyl-phosphate synthase, large subunit [Vibrio cholerae 2740-80... CARB_VIBCH - Carbamoyl-phosphate synthase large chain OS=Vibrio cholerae GN=carB PE=3 SV=1 gi\|124113657, gi... - gi\|153217328\|ref\|ZP_01951079.1\| carbamoyl-phosphate synthase, large subunit [Vibrio cholerae 1587], ... gi\|153225032, gi... - gi\|153225032\|ref\|ZP_01954678.1\| carbamoyl-phosphate synthase, large subunit [Vibrio cholerae MAK 757...	0.0	[433..1506]	[2..1072]
gi\|1518088, gi\|1... - gi\|185132254\|ref\|NP_001118181.1\| carbamoyl-phosphate synthetase III [Oncorhynchus mykiss], gi\|151808...	0.0	[6..1501]	[27..1491]
CARB_RHILO - Carbamoyl-phosphate synthase large chain OS=Rhizobium loti GN=carB PE=3 SV=1 CARB_RHILO - Carbamoyl-phosphate synthase large chain OS=Rhizobium loti (strain MAFF303099) GN=carB PE=3 SV=1	0.0	[433..1503]	[2..1167]
gi\|5499725 - gi\|5499725\|gb\|AAD43968.1\|AF119250_1 carbamoyl-phosphate synthetase III [Alcolapia grahami]	0.0	[11..1502]	[34..1494]
CARB_NEIMA - Carbamoyl-phosphate synthase large chain OS=Neisseria meningitidis serogroup A / serotype 4A (strain... CARB_NEIMA - Carbamoyl-phosphate synthase large chain OS=Neisseria meningitidis serogroup A GN=carB PE=3 SV=1 gi\|11272704 - pir\|\|F81979 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) large chain NMA0602 [i...	0.0	[433..1506]	[2..1068]

Back

Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATIAPTAPI TPPMESTGDR LVTLELKDGT VLQGYSFGAE KSVAGELVFQ TGMVGYPESV  60
   61 TDPSYEGQIL VITYPLVGNY GVPDMHLRDE LVEELPRYFE SNRIHIAGLV ISHYTDEYSH 120
  121 YLRKSSLGKW LQNEGIPAVY GVDTRSLTKH LRDAGSMLGR LSLEKSGSDR TISRSSSWRS 180
  181 AFDVPEWVDP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	764.0
Match:	1bxrB_
Description:	Carbamoyl phosphate synthetase, small subunit N-terminal domain; Carbamoyl phosphate synthetase, small subunit C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	11.6556846811261	bayes_pls_golite062009
carbamoyl-phosphate synthase activity	11.614541080865	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	8.83104490344765	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	6.7523653122648	bayes_pls_golite062009
ligase activity	2.64230127203047	bayes_pls_golite062009
nucleic acid binding	1.83357525248647	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.68223120807504	bayes_pls_golite062009
kinase activity	1.67508566693087	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.57588199570083	bayes_pls_golite062009
transferase activity	1.56222597521764	bayes_pls_golite062009
phosphoribosylformylglycinamidine synthase activity	1.51568729563523	bayes_pls_golite062009
binding	1.22860407524238	bayes_pls_golite062009
catalytic activity	0.902495165806215	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.774587372455935	bayes_pls_golite062009
hydrolase activity	0.488948677783382	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.270391651600004	bayes_pls_golite062009
anthranilate synthase activity	0.243205818526006	bayes_pls_golite062009
peptidase activity	0.0466975117232061	bayes_pls_golite062009
protein binding	0.0152024556625711	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [191-422]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVQNLVSKVS INEPKLYVPP ADNKHIELQT GPDGKVLRIL AIDVGMKYNQ IRCFIKRGVE  60
   61 LKVVPWNYDF TKEDYDGLFI SNGPGDPSVL DDLSQRLSNV LEAKKTPVFG ICLGHQLIAR 120
  121 AAGASTLKLK FGNRGHNIPC TSTISGRCYI TSQNHGFAVD VDTLTSGWKP LFVNANDDSN 180
  181 EGIYHSELPY FSVQFHPEST PGPRDTEFLF DVFIQAVKEF KYTQVLKPIA FP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	764.0
Match:	1bxrB_
Description:	Carbamoyl phosphate synthetase, small subunit N-terminal domain; Carbamoyl phosphate synthetase, small subunit C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbamoyl-phosphate synthase activity	10.3961907577933	bayes_pls_golite062009
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	10.3817460390594	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	7.55690629692775	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	6.95559501787172	bayes_pls_golite062009
carbamoyl-phosphate synthase (ammonia) activity	5.29301695671381	bayes_pls_golite062009
aspartate carbamoyltransferase activity	3.38433995801364	bayes_pls_golite062009
ligase activity	3.1029847500488	bayes_pls_golite062009
dihydroorotase activity	2.87758723400434	bayes_pls_golite062009
succinate-CoA ligase activity	2.77725772893528	bayes_pls_golite062009
carboxyl- or carbamoyltransferase activity	2.46049425383361	bayes_pls_golite062009
acid-amino acid ligase activity	2.05746473175561	bayes_pls_golite062009
CoA-ligase activity	1.95069402824125	bayes_pls_golite062009
binding	1.94172111366073	bayes_pls_golite062009
acid-thiol ligase activity	1.72672517234442	bayes_pls_golite062009
transferase activity	1.65470153555003	bayes_pls_golite062009
phosphoribosylaminoimidazole carboxylase activity	1.57708889650281	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.43253315277789	bayes_pls_golite062009
catalytic activity	1.08688404807699	bayes_pls_golite062009
phosphoribosylamine-glycine ligase activity	1.04915286326924	bayes_pls_golite062009
carbon-oxygen lyase activity, acting on phosphates	0.964679554894316	bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds	0.96165574211624	bayes_pls_golite062009
biotin carboxylase activity	0.925630424589009	bayes_pls_golite062009
phosphoribosylaminoimidazolecarboxamide formyltransferase activity	0.898425265043358	bayes_pls_golite062009
hydrolase activity	0.756177577540965	bayes_pls_golite062009
succinate-CoA ligase (ADP-forming) activity	0.731047220665703	bayes_pls_golite062009
carbon-oxygen lyase activity	0.482425669839603	bayes_pls_golite062009
protein binding	0.455938814211606	bayes_pls_golite062009
lyase activity	0.432948879967458	bayes_pls_golite062009
acetyl-CoA carboxylase activity	0.39538073184604	bayes_pls_golite062009
propionyl-CoA carboxylase activity	0.377204236873769	bayes_pls_golite062009
ATP binding	0.268802736141542	bayes_pls_golite062009
adenyl ribonucleotide binding	0.245910202001696	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	0.2431211195117	bayes_pls_golite062009
adenyl nucleotide binding	0.23797201509664	bayes_pls_golite062009
glutathione binding	0.20743435331623	bayes_pls_golite062009
nucleotide binding	0.106800787341606	bayes_pls_golite062009
ribonucleotide binding	0.105378337351009	bayes_pls_golite062009
purine nucleotide binding	0.105328960473132	bayes_pls_golite062009
purine ribonucleotide binding	0.105164298301833	bayes_pls_golite062009
glutathione synthase activity	0.0685848191991462	bayes_pls_golite062009
succinate-CoA ligase (GDP-forming) activity	0.04189990190488	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [423-573]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGLLEDNVKA HPRIEAKKVL VLGSGGLSIG QAGEFDYSGS QAIKALKEEG IYTILINPNI  60
   61 ATIQTSKGLA DKVYFVPVTA EFVRKVILHE RPDAIYVTFG GQTALSVGIA MKDEFEALGV 120
  121 KVLGTPIDTI ITTEDRELFS NAIDEINEKC A

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [637-779]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGWKEVEYE VVRDAFDNCI TVCNMENFDP LGIHTGDSIV VAPSQTLSDE DYNMLRTTAV  60
   61 NVIRHLGVVG ECNIQYALNP VSKDYCIIEV NARLSRSSAL ASKATGYPLA YTAAKLGLNI 120
  121 PLNEVKNSVT KSTCACFEPS LDY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11000.0
Match:	1a9xA_
Description:	Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
dihydroorotase activity	5.83804402298952	bayes_pls_golite062009
hydrolase activity	3.43682651851542	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	3.03591306120652	bayes_pls_golite062009
transcription regulator activity	2.05422491012934	bayes_pls_golite062009
deaminase activity	1.79186203771221	bayes_pls_golite062009
nucleic acid binding	1.75483241027992	bayes_pls_golite062009
catalytic activity	1.70199291046899	bayes_pls_golite062009
DNA binding	1.70075498563244	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.60895003474033	bayes_pls_golite062009
binding	1.20793368650496	bayes_pls_golite062009
transcription factor activity	1.01581417842484	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.573107361273483	bayes_pls_golite062009
deacetylase activity	0.57075565732108	bayes_pls_golite062009
guanine deaminase activity	0.134430884998957	bayes_pls_golite062009
dihydropyrimidinase activity	0.101722148781441	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [574-636]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSQAANSVDE ALAAVKEIGF PVIVRAAYAL GGLGSGFANN EKELVDLCNV AFSSSPQVLV  60
   61 EKS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [780-890]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CVVKMPRWDL KKFTRVSTEL SSSMKSVGEV MSIGRTFEEA IQKAIRSTEY ANLGFNETDL  60
   61 DIDIDYELNN PTDMRVFAIA NAFAKKGYSV DKVWEMTRID KWFLNKLHDL V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11000.0
Match:	1a9xA_
Description:	Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [891-964]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QFAEKISSFG TKEELPSLVL RQAKQLGFDD RQIARFLDSN EVAIRRLRKE YGITPFVKQI  60
   61 DTVAAEFPAY TNYL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11000.0
Match:	1a9xA_
Description:	Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carboxyl- or carbamoyltransferase activity	8.44774290170513	bayes_pls_golite062009
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	8.39877026738977	bayes_pls_golite062009
carbamoyl-phosphate synthase activity	8.35868658131065	bayes_pls_golite062009
aspartate carbamoyltransferase activity	7.47628089321489	bayes_pls_golite062009
ornithine carbamoyltransferase activity	6.08861672645671	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	5.70428077078256	bayes_pls_golite062009
transferase activity	4.46011936943199	bayes_pls_golite062009
dihydroorotase activity	4.10312514971972	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	4.09429261864362	bayes_pls_golite062009
aspartate binding	3.43574933938267	bayes_pls_golite062009
UTP binding	3.43574933938267	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	2.1749430001471	bayes_pls_golite062009
catalytic activity	2.06069688716378	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.71477949033699	bayes_pls_golite062009
kinase activity	1.70283432187593	bayes_pls_golite062009
binding	1.63251597999268	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.5976562586299	bayes_pls_golite062009
protein kinase activity	1.48895685647086	bayes_pls_golite062009
hydrolase activity	0.628276058923848	bayes_pls_golite062009
ligase activity	0.345534785035194	bayes_pls_golite062009
amine binding	0.33918556173094	bayes_pls_golite062009
protein binding	0.271043612914069	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	0.254873181665999	bayes_pls_golite062009

Predicted Domain #6

Region A:
Residues: [965-1086]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YMTYNADSHD LSFDDHGVMV LGSGVYRIGS SVEFDWCAVT AVRTLRANNI KTIMVNYNPE  60
   61 TVSTDYDEAD RLYFETINLE RVLDIYEIEN SSGVVVSMGG QTSNNIAMTL HRENVKILGT 120
  121 SP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11000.0
Match:	1a9xA_
Description:	Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
Matching Structure (courtesy of the PDB):

Predicted Domain #7

Region A:
Residues: [1087-1110]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMIDSAENRY KFSRMLDQIG VDQP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [1176-1356]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IENAKEIEMD AVARNGELVM HVVSEHVENA GVHSGDATLI VPPQDLAPET VDRIVVATAK  60
   61 IGKALKITGP YNIQFIAKDN EIKVIECNVR ASRSFPFISK VVGVNLIELA TKAIMGLPLT 120
  121 PYPVEKLPDD YVAVKVPQFS FPRLAGADPV LGVEMASTGE VATFGHSKYE AYLKSLLATG 180
  181 F

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [1484-1490]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AISRNIT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11000.0
Match:	1a9xA_
Description:	Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
Matching Structure (courtesy of the PDB):

Predicted Domain #8

Region A:
Residues: [1111-1175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AWKELTSMDE AESFAEKVGY PVLVRPSYVL SGAAMNTVYS KNDLESYLNQ AVEVSRDYPV  60
   61 VITKY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [1357-1483]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLPKKNILLS IGSYKEKQEL LSSVQKLYNM GYKLFATSGT ADFLSEHGIA VQYLEVLNKD  60
   61 DDDQKSEYSL TQHLANNEID LYINLPSANR FRRPASYVSK GYKTRRLAVD YSVPLVTNVK 120
  121 CAKLLIE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11000.0
Match:	1a9xA_
Description:	Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
Matching Structure (courtesy of the PDB):

Predicted Domain #9

Region A:
Residues: [1491-1837]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDVSERDAQT SHRTITLPGL INIATYVPNA SHVIKGPAEL KETTRLFLES GFTYCQLMPR  60
   61 SISGPVITDV ASLKAANSVS QDSSYTDFSF TIAGTAHNAH SVTQSASKVT ALFLPLRELK 120
  121 NKITAVAELL NQWPTEKQVI AEAKTADLAS VLLLTSLQNR SIHITGVSNK EDLALIMTVK 180
  181 AKDPRVTCDV NIYSLFIAQD DYPEAVFLPT KEDQEFFWNN LDSIDAFSVG ALPVALANVT 240
  241 GNKVDVGMGI KDSLPLLLAA VEEGKLTIDD IVLRLHDNPA KIFNIPTQDS VVEIDLDYSF 300
  301 RRNKRWSPFN KDMNGGIERV VYNGETLVLS GELVSPGAKG KCIVNPS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.0
Match:	1gkrA_
Description:	L-hydantoinase
Matching Structure (courtesy of the PDB):

Predicted Domain #10

Region A:
Residues: [1838-1897]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PASITASAEL QSTSAKRRFS ITEEAIADNL DAAEDAIPEQ PLEQKLMSSR PPRELVAPGA  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.622	d.120.1	Cytochrome b5
View	Download	0.405	b.40.2	Bacterial enterotoxins
View	Download	0.493	a.64.1	Saposin
View	Download	0.360	a.144.1	PABC (PABP) domain
View	Download	0.427	a.179.1	Replisome organizer (g39p helicase loader/inhibitor protein)
View	Download	0.351	b.40.4	Nucleic acid-binding proteins
View	Download	0.303	a.144.1	PABC (PABP) domain
View	Download	0.232	b.71.1	Glycosyl hydrolase domain
View	Download	0.221	b.40.4	Nucleic acid-binding proteins
View	Download	0.217	g.62.1	Cysteine-rich DNA binding domain, (DM domain)
View	Download	0.215	a.60.1	SAM/Pointed domain
View	Download	0.213	a.8.1	Bacterial immunoglobulin/albumin-binding domains

Predicted Domain #11

Region A:
Residues: [1898-1946]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQNLIRSNNP FRGRHILSIK QFKRSDFHVL FAVAQELRAA VAREGVLDL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [2034-2046]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGSREHPTQA FLD

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [2195-2214]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYGLFVRMA LLAMVMGVDM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	717.9691
Match:	1ekxA_
Description:	Aspartate carbamoyltransferase catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #12

Region A:
Residues: [1947-2033]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGHVITTIF FEPSTRTCSS FIAAMERLGG RIVNVNPLVS SVKKGETLQD TIRTLACYSD  60
   61 AIVMRHSEEM SVHIAAKYSP VPIINGG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [2047-2194]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFTIREEIGT VNGITVTFMG DLKHGRTVHS LCRLLMHYQV RINLVSPPEL RLPEGLREEL  60
   61 RKAGLLGVES IELTPHIISK TDVLYCTRVQ EERFNSPEEY ARLKDTYIVD NKILAHAKEN 120
  121 MAIMHPLPRV NEIKEEVDYD HRAAYFRQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	717.9691
Match:	1ekxA_
Description:	Aspartate carbamoyltransferase catalytic subunit
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions:

Predicted functions:

Predicted functions: