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View Structure Prediction Details

Protein: MDV1
Organism: Saccharomyces cerevisiae
Length: 714 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDV1.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [16..714] [849..1481]
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain ATCC 27184 / PCC 6...
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain PCC 6803 / Kazusa)...
gi|7446132 - pir||S76086 beta transducin-like protein, 190K - Synechocystis sp. (strain PCC 6803)
0.0 [13..685] [1029..1668]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
0.0 [65..625] [823..1314]

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Predicted Domain #1
Region A:
Residues: [1-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVNDQITHI GKTLSTTASA FLNYQKSNSN TQDVLTNNGP YKNLLSNTVN NASSTSYFYK  60
   61 RTEHGRFVKN ASNTFEDIYS KTRRGDVFRN KFTDNKTCFR MLTYISDDLL NEIPTKEGLK 120
  121 SDADGKLLTE GGENENLRKN ASKKETSLFQ GFKSYLPIAE LAIENTERLN YDTNGTSGTV 180
  181 GAKDVMSKTN ERDEIHTELP NFQDSFLIPP GVETKKISSS YSPSALKSFS QTLVNSLEFL 240
  241 NIQKNSTLSE IRDIEVEVEN LRQKKEKLLG KIANIEQNQL LLEDNLKQID DRLDFLEEYG 300
  301 LEVIEANSDE NAEDDGMSER KALKNDAIRN EGVTTESISS EASNLPPRRR QQLRDDNSLN 360
  361 RLGAFYSKSK KRHRKSFPTF QQLYEPGTKI GSIMSTHDDF LTCLDFDAPF GTLCTAGYLD 420
  421 HTVKIWDLSK QNKIGELAGH LATINCMQIN RDYGTLVTGG RDAALKLWNL NLAQQLYQET 480
  481 QNLTSPTNHI DSPCVHTFEA HTDEVTALSL DPSFLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.522879
Match: 1k32A_
Description: Tricorn protease; Tricorn protease N-terminal domain; Tricorn protease domain 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.31804728298431 bayes_pls_golite062009
GTPase activity 3.23750443966606 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 2.299832037975 bayes_pls_golite062009
snoRNA binding 2.20077763915561 bayes_pls_golite062009
dynactin binding 1.92897254169098 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
actin filament binding 1.5197243426595 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.22384651674093 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
receptor activity 1.12819778129653 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 1.06323957405727 bayes_pls_golite062009
microtubule plus-end binding 1.01166033978052 bayes_pls_golite062009
molecular transducer activity 0.974380908248463 bayes_pls_golite062009
signal transducer activity 0.974380908248463 bayes_pls_golite062009
angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
type 1 angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
0.88172763425403 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
transcription repressor activity 0.658573452658359 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
dynein intermediate chain binding 0.443846546939402 bayes_pls_golite062009
receptor binding 0.316169754698691 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
G-protein-coupled receptor binding 0.251120087240234 bayes_pls_golite062009
ligase activity 0.20682813699621 bayes_pls_golite062009
transcription corepressor activity 0.182612389752591 bayes_pls_golite062009
histone binding 0.166694897714113 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
structural molecule activity 0.0588151480189092 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [517-714]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGSQDRTIRQ WDLRSGKCLQ TIDLSFANVL TTSTNVDLSK STLLTQRNER PSIGALQSFD  60
   61 AALATGTKDG VVRLWDLRSG KVIRTLKGHT DAITSLKFDS ACLVTGSYDR TVRIWDLRTG 120
  121 LLNKFHAYSA PVLSLDLFQE NAAVVVADEP SVQIYDSEKD ESWSCVEQGN ETSVSTVKYK 180
  181 ENYMVEGREN GDVNIWAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 185.751666
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [633-714]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRTGLLNKFH AYSAPVLSLD LFQENAAVVV ADEPSVQIYD SEKDESWSCV EQGNETSVST  60
   61 VKYKENYMVE GRENGDVNIW AV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.522879
Match: 2ovpB
Description: No description for 2ovpB was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle