| Protein: | MLP2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1679 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MLP2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [269..1433] | [774..1939] |
|
|
0.0 | [259..1428] | [766..1929] |
|
|
0.0 | [269..1433] | [775..1940] |
|
Region A: Residues: [1-175] |
1 11 21 31 41 51
| | | | | |
1 MEDKISEFLN VPFESLQGVT YPVLRKLYKK IAKFERSEEE VTKLNVLVDE IKSQYYSRIS 60
61 KLKQLLDESS EQKNTAKEEL NGLKDQLNEE RSRYRREIDA LKKQLHVSHE AMREVNDEKR 120
121 VKEEYDIWQS RDQGNDSLND DLNKENKLLR RKLMEMENIL QRCKSNAISL QLKYD
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [176-268] |
1 11 21 31 41 51
| | | | | |
1 TSVQEKELML QSKKLIEEKL SSFSKKTLTE EVTKSSHVEN LEEKLYQMQS NYESVFTYNK 60
61 FLLNQNKQLS QSVEEKVLEM KNLKDTASVE KAE
|
| Detection Method: | |
| Confidence: | 9.522879 |
| Match: | 1c1gA_ |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [269-692] |
1 11 21 31 41 51
| | | | | |
1 FSKEMTLQKN MNDLLRSQLT SLEKDCSLRA IEKNDDNSCR NPEHTDVIDE LIDTKLRLEK 60
61 SKNECQRLQN IVMDCTKEEE ATMTTSAVSP TVGKLFSDIK VLKRQLIKER NQKFQLQNQL 120
121 EDFILELEHK TPELISFKER TKSLEHELKR STELLETVSL TKRKQEREIT SLRQKINGCE 180
181 ANIHSLVKQR LDLARQVKLL LLNTSAIQET ASPLSQDELI SLRKILESSN IVNENDSQAI 240
241 ITERLVEFSN VNELQEKNVE LLNCIRILAD KLENYEGKQD KTLQKVENQT IKEAKDAIIE 300
301 LENINAKMET RINILLRERD SYKLLASTEE NKANTNSVTS MEAAREKKIR ELEAELSSTK 360
361 VENSAIIQNL RKELLIYKKS QCKKKTTLED FENFKGLAKE KERMLEEAID HLKAELEKQK 420
421 SWVP
|
| Detection Method: | |
| Confidence: | 48.980454 |
| Match: | 1i84S_ |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [693-745] |
1 11 21 31 41 51
| | | | | |
1 SYIHVEKERA STELSQSRIK IKSLEYEISK LKKETASFIP TKESLTRDFE QCC
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [746-1092] |
1 11 21 31 41 51
| | | | | |
1 KEKKELQMRL KESEISHNEN KMDFSSKEGQ YKAKIKELEN NLERLRSDLQ SKIQEIESIR 60
61 SCKDSQLKWA QNTIDDTEMK MKSLLTELSN KETTIEKLSS EIENLDKELR KTKFQYKFLD 120
121 QNSDASTLEP TLRKELEQIQ VQLKDANSQI QAYEEIISSN ENALIELKNE LAKTKENYDA 180
181 KIELEKKEKW AREEDLSRLR GELGEIRALQ PKLKEGALHF VQQSEKLRNE VERIQKMIEK 240
241 IEKMSTIVQL CKKKEMSQYQ STMKENKDLS ELVIRLEKDA ADCQAELTKT KSSLYSAQDL 300
301 LDKHERKWME EKADYERELI SNIEQTESLR VENSVLIEKV DDTAANN
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1093-1169] |
1 11 21 31 41 51
| | | | | |
1 GDKDHLKLVS LFSNLRHERN SLETKLTTCK RELAFVKQKN DSLEKTINDL QRTQTLSEKE 60
61 YQCSAVIIDE FKDITKE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.923 | 0.005 | nuclear envelope | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.20953772435302 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.41271657675151 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.26183812259792 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.1457670954804 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| transcription activator activity | 1.77700860354597 | bayes_pls_golite062009 |
| actin binding | 1.48871115327078 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.14886080629275 | bayes_pls_golite062009 |
| chromatin binding | 0.876241359231159 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| protein binding | 0.830419844171551 | bayes_pls_golite062009 |
| molecular transducer activity | 0.515227322986114 | bayes_pls_golite062009 |
| signal transducer activity | 0.515227322986114 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.377270323657906 | bayes_pls_golite062009 |
| receptor activity | 0.361249991204582 | bayes_pls_golite062009 |
| RNA binding | 0.329588635205335 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.2679415219517 | bayes_pls_golite062009 |
| actin filament binding | 0.26311995282891 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.147724557486814 | bayes_pls_golite062009 |
|
Region A: Residues: [1170-1603] |
1 11 21 31 41 51
| | | | | |
1 VTQVNILKEN NAILQKSLKN VTEKNREIYK QLNDRQEEIS RLQRDLIQTK EQVSINSNKI 60
61 LVYESEMEQC KQRYQDLSQQ QKDAQKKDIE KLTNEISDLK GKLSSAENAN ADLENKFNRL 120
121 KKQAHEKLDA SKKQQAALTN ELNELKAIKD KLEQDLHFEN AKVIDLDTKL KAHELQSEDV 180
181 SRDHEKDTYR TLMEEIESLK KELQIFKTAN SSSDAFEKLK VNMEKEKDRI IDERTKEFEK 240
241 KLQETLNKST SSEAEYSKDI ETLKKEWLKE YEDETLRRIK EAEENLKKRI RLPSEERIQK 300
301 IISKRKEELE EEFRKKLKEN AGSLTFLDNK GSGEDAEEEL WNSPSKGNSE RPSAVAGFIN 360
361 QKNLKPQEQL KNVKNDVSFN DSQSMVTNKE NNIVDSSAAG NKAIPTFSFG KPFFSSNTSS 420
421 LQSFQNPFTA SQSN
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1604-1679] |
1 11 21 31 41 51
| | | | | |
1 INTNAPLRTL NIQPEVAVKA AINFSNVTDL TNNSTDGAKI TEIGSTSKRP IESGTSSDPD 60
61 TKKVKESPAN DQASNE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
