| Protein: | PRP22 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1145 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRP22.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1145] | [1..1144] |
|
|
0.0 | [1..1145] | [1..1145] |
|
|
0.0 | [1..1135] | [10..1165] |
|
|
0.0 | [173..1137] | [260..1220] |
|
|
0.0 | [246..1114] | [468..1369] |
|
|
0.0 | [217..1143] | [192..1106] |
|
|
0.0 | [321..1139] | [364..1199] |
|
Region A: Residues: [1-122] |
1 11 21 31 41 51
| | | | | |
1 MSDISKLIGA IVGSDDPVII EFVLNIINKS GNLQEFIRNI QKLDAGISYE DSIKMYNAFL 60
61 GKQEEEKVRN KVKSSPLSQK INQVLKDDVN LDDPVVTEFV LSILNKSKSI TEFQEQLNLM 120
121 QS
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| 4.75811129307632 | bayes_pls_golite062009 | |
| transcription termination factor activity | 4.27506184839126 | bayes_pls_golite062009 |
| RNA binding | 4.05373509885278 | bayes_pls_golite062009 |
| structural constituent of ribosome | 3.73145378633995 | bayes_pls_golite062009 |
| transcription regulator activity | 3.24341202600661 | bayes_pls_golite062009 |
| structural molecule activity | 3.16728233432927 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.81524862921454 | bayes_pls_golite062009 |
| binding | 1.7774714353448 | bayes_pls_golite062009 |
| mRNA binding | 1.6485756688073 | bayes_pls_golite062009 |
| single-stranded DNA binding | 1.62996999055328 | bayes_pls_golite062009 |
| nucleic acid binding | 1.45130233071198 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 1.35850109411274 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 1.35845277283398 | bayes_pls_golite062009 |
| ligase activity, forming aminoacyl-tRNA and related compounds | 1.35845277283398 | bayes_pls_golite062009 |
| ribonuclease activity | 1.19236946227657 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 1.15212468568198 | bayes_pls_golite062009 |
| exoribonuclease activity | 1.10445667068538 | bayes_pls_golite062009 |
| DNA binding | 1.01454217691792 | bayes_pls_golite062009 |
| 3'-5'-exoribonuclease activity | 0.83268201349295 | bayes_pls_golite062009 |
| second spliceosomal transesterification activity | 0.448378021030889 | bayes_pls_golite062009 |
| protein binding | 0.423986689445573 | bayes_pls_golite062009 |
| ligase activity | 0.346041081217685 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.32084431704638 | bayes_pls_golite062009 |
| transcription factor activity | 0.298729064067577 | bayes_pls_golite062009 |
| translation regulator activity | 0.22908707234671 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.179682348023561 | bayes_pls_golite062009 |
| aspartate-tRNA ligase activity | 0.151650064901878 | bayes_pls_golite062009 |
| translation initiation factor activity | 0.11625379846973 | bayes_pls_golite062009 |
| catalytic activity | 0.10089766806364 | bayes_pls_golite062009 |
| DNA-directed RNA polymerase activity | 0.0740938021136293 | bayes_pls_golite062009 |
| RNA polymerase activity | 0.0740938021136293 | bayes_pls_golite062009 |
|
Region A: Residues: [123-282] |
1 11 21 31 41 51
| | | | | |
1 GLDNETIFKI YQIASPPVMK EEVSVLPSTK IPAKIEAKIE EEVQKIESLD PSPVLHKVYE 60
61 GKVRNITTFG CFVQIFGTRM KNCDGLVHIS EMSDQRTLDP HDVVRQGQHI FVEVIKIQNN 120
121 GKISLSMKNI DQHSGEIRKR NTESVEDRGR SNDAHTSRNM
|
| Detection Method: | |
| Confidence: | 98.144602 |
| Match: | 1sro__ |
| Description: | S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [283-432] |
1 11 21 31 41 51
| | | | | |
1 KNKIKRRALT SPERWEIRQL IASGAASIDD YPELKDEIPI NTSYLTAKRD DGSIVNGNTE 60
61 KVDSKLEEQQ RDETDEIDVE LNTDDGPKFL KDQQVKGAKK YEMPKITKVP RGFMNRSAIN 120
121 GSNAIRDHRE EKLRKKREIE QQIRKQQSFD
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| 4.704140727858 | bayes_pls_golite062009 | |
| binding | 2.44689197844883 | bayes_pls_golite062009 |
| RNA binding | 2.29590582680214 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.57653963868443 | bayes_pls_golite062009 |
| RNA helicase activity | 1.42791449104435 | bayes_pls_golite062009 |
| nucleic acid binding | 1.41477043612798 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 1.39335733374328 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 1.36724390116598 | bayes_pls_golite062009 |
| DNA binding | 1.11699929651302 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| transcription regulator activity | 0.989226939888218 | bayes_pls_golite062009 |
| mRNA binding | 0.76699944561918 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.652333406433794 | bayes_pls_golite062009 |
| helicase activity | 0.6191010101321 | bayes_pls_golite062009 |
| motor activity | 0.61636596887462 | bayes_pls_golite062009 |
| structural molecule activity | 0.596382945962261 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.461763181659193 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.458831409927227 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.455976987338331 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.422944846459286 | bayes_pls_golite062009 |
| snRNA binding | 0.418985924846052 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| translation release factor activity | 0.178286731022211 | bayes_pls_golite062009 |
| translation termination factor activity | 0.151456842619444 | bayes_pls_golite062009 |
| nucleotide binding | 0.114848452385726 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.10713474095071 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.0916519414118148 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.0915913646217636 | bayes_pls_golite062009 |
| protein binding | 0.071010918255742 | bayes_pls_golite062009 |
| transcription factor activity | 0.0434163635422169 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.0272673919333979 | bayes_pls_golite062009 |
|
Region A: Residues: [433-661] |
1 11 21 31 41 51
| | | | | |
1 DPTKNKKDSR NEIQMLKNQL IVTEWEKNRM NESISYGKRT SLPISAQRQT LPVYAMRSEL 60
61 IQAVRDNQFL VIVGETGSGK TTQITQYLDE EGFSNYGMIG CTQPRRVAAV SVAKRVAEEV 120
121 GCKVGHDVGY TIRFEDVTGP DTRIKYMTDG MLQREALLDP EMSKYSVIML DEAHERTVAT 180
181 DVLFALLKKA AIKRPELKVI VTSATLNSAK FSEYFLNCPI INIPGKTFP
|
| Detection Method: | |
| Confidence: | 9.154902 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [662-833] |
1 11 21 31 41 51
| | | | | |
1 VEVLYSQTPQ MDYIEAALDC VIDIHINEGP GDILVFLTGQ EEIDSCCEIL YDRVKTLGDS 60
61 IGELLILPVY SALPSEIQSK IFEPTPKGSR KVVFATNIAE TSITIDGIYY VVDPGFAKIN 120
121 IYNARAGIEQ LIVSPISQAQ ANQRKGRAGR TGPGKCYRLY TESAFYNEML EN
|
| Detection Method: | |
| Confidence: | 9.154902 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [834-1145] |
1 11 21 31 41 51
| | | | | |
1 TVPEIQRQNL SHTILMLKAM GINDLLKFDF MDPPPKNLML NALTELYHLQ SLDDEGKLTN 60
61 LGKEMSLFPM DPTLSRSLLS SVDNQCSDEI VTIISMLSVQ NVFYRPKDRQ LEADSKKAKF 120
121 HHPYGDHLTL LNVYTRWQQA NYSEQYCKTN FLHFRHLKRA RDVKSQISMI FKKIGLKLIS 180
181 CHSDPDLIRK TFVSGFFMNA AKRDSQVGYK TINGGTEVGI HPSSSLYGKE YEYVMYHSIV 240
241 LTSREYMSQV TSIEPQWLLE VAPHFYKAGD AESQSRKKAK IIPLHNKFAK DQNSWRLSSI 300
301 RQSRERALGI KR
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
