Protein: | HDA2 |
Organism: | Saccharomyces cerevisiae |
Length: | 674 amino acids |
Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HDA2.
Description | E-value | Query Range |
Subject Range |
|
5.0E-62 | [73..668] | [843..1442] |
|
4.0E-61 | [73..668] | [846..1445] |
|
1.0E-60 | [73..668] | [57..656] |
|
2.0E-60 | [73..668] | [848..1447] |
|
2.0E-60 | [73..668] | [841..1440] |
Region A: Residues: [1-59] |
1 11 21 31 41 51 | | | | | | 1 MSRKNSKKLK VYYLPVTLTQ FQKDLSEILI SLHAKSFKAS IIGEPQADAV NKPSGLPAG |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [60-391] |
1 11 21 31 41 51 | | | | | | 1 PETHPYPTLS QRQLTYIFDS NIRAIANHPS LLVDHYMPRQ LLRMEPTESS IAGSHKFQVL 60 61 NQLINSICFR DREGSPNEVI KCAIIAHSIK ELDLLEGLIL GKKFRTKRLS GTSLYNEKHK 120 121 FPNLPTVDST INKDGTPNSV SSTSSNSNST SYTGYSKDDY DYSVKRNLKK RKINTDDWLF 180 181 LATTKHLKHD QYLLANYDID MIISFDPMLE VELPALQVLR NNANKDIPII KLLVQNSPDH 240 241 YLLDSEIKNS SVKSSHLSNN GHVDDSQEYE EIKSSLLYFL QARNAPVNNC EIDYIKLVKC 300 301 CLEGKDCNNI LPVLDLITLD EASKDSSDSG FW |
Detection Method: | ![]() |
Confidence: | 17.154902 |
Match: | 1i84S_ |
Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [392-498] |
1 11 21 31 41 51 | | | | | | 1 QPQLTKLQYS STELPLWDGP LDIKTYQTEL MHRAVIRLRD IQDEYAKGTV PLYEKRLNET 60 61 QRQNQLDEIK NSVGLTFKKK QEVEKSINDS EKRLKHAMTE STKLQNK |
Detection Method: | ![]() |
Confidence: | 8.69897 |
Match: | 1c1gA_ |
Description: | Tropomyosin |
Matching Structure (courtesy of the PDB):![]() |
Term | Confidence | Notes |
protein deacetylase activity | 6.89067246450687 | bayes_pls_golite062009 |
histone deacetylase activity | 6.72973102400173 | bayes_pls_golite062009 |
deacetylase activity | 6.17788760083229 | bayes_pls_golite062009 |
transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 5.08778624990141 | bayes_pls_golite062009 |
DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
nucleic acid binding | 4.51452285155271 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 4.31765999651746 | bayes_pls_golite062009 |
transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
transcription repressor activity | 3.55154985983449 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 3.16896789933192 | bayes_pls_golite062009 |
binding | 3.02779747447702 | bayes_pls_golite062009 |
sequence-specific DNA binding | 2.41271657675151 | bayes_pls_golite062009 |
lysine N-acetyltransferase activity | 1.90369937566383 | bayes_pls_golite062009 |
histone acetyltransferase activity | 1.90369937566383 | bayes_pls_golite062009 |
transcription activator activity | 1.77700860354597 | bayes_pls_golite062009 |
specific RNA polymerase II transcription factor activity | 1.73068440195944 | bayes_pls_golite062009 |
chromatin binding | 1.68956710349366 | bayes_pls_golite062009 |
general RNA polymerase II transcription factor activity | 1.62096064323298 | bayes_pls_golite062009 |
transcription corepressor activity | 1.49423102874486 | bayes_pls_golite062009 |
transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
protein binding | 0.830419844171551 | bayes_pls_golite062009 |
N-acyltransferase activity | 0.712553030350746 | bayes_pls_golite062009 |
histone binding | 0.557787598121402 | bayes_pls_golite062009 |
N-acetyltransferase activity | 0.474709214154094 | bayes_pls_golite062009 |
transcription coactivator activity | 0.2679415219517 | bayes_pls_golite062009 |
transferase activity, transferring phosphorus-containing groups | 0.141400887946529 | bayes_pls_golite062009 |
Region A: Residues: [499-674] |
1 11 21 31 41 51 | | | | | | 1 INHLLKNRQE LENFNKLPSN TISSENHLEE GSALADKLKE YIDKNATLFN KLKELQQANA 60 61 EKSKLNDELR SKYQIESSKA AESAQTLKIL QESMKSLENE VNGPLTKFST ESLKKELERL 120 121 QNDFQSLKAR NKFLKNYITL MNRQYDLKNK NNVQVEKAAA NGTRFRSTRS NTPNYT |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.