| Protein: | PIM1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1133 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIM1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1133] | [1..1133] |
|
|
0.0 | [91..1125] | [69..1056] |
|
|
0.0 | [90..1124] | [53..1055] |
|
|
0.0 | [142..1118] | [71..948] |
|
|
0.0 | [261..1113] | [6..772] |
|
|
0.0 | [261..1112] | [10..776] |
|
|
0.0 | [261..1113] | [13..779] |
|
|
0.0 | [261..1113] | [6..772] |
|
|
0.0 | [142..1118] | [71..947] |
|
Region A: Residues: [1-155] |
1 11 21 31 41 51
| | | | | |
1 MLRTRTTKTL STVARTTRAI QYYRSIAKTA AVSQRRFAST LTVRDVENIK PSHIIKSPTW 60
61 QEFQHQLKDP RYMEHFAQLD AQFARHFMAT NSGKSILAKD DSTSQKKDED VKIVPDEKDT 120
121 DNDVEPTRDD EIVNKDQEGE ASKNSRSSAS GGGQS
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [156-387] |
1 11 21 31 41 51
| | | | | |
1 SSSRSDSGDG SSKQKPPKDV PEVYPQMLAL PIARRPLFPG FYKAVVISDE RVMKAIKEML 60
61 DRQQPYIGAF MLKNSEEDTD VITDKNDVYD VGVLAQITSA FPSKDEKTGT ETMTALLYPH 120
121 RRIKIDELFP PNEEKEKSKE QAKDTDTETT VVEDANNPED QESTSPATPK LEDIVVERIP 180
181 DSELQHHKRV EATEEESEEL DDIQEGEDIN PTEFLKNYNV SLVNVLNLED EP
|
| Detection Method: | |
| Confidence: | 71.744727 |
| Match: | PF02190 |
| Description: | ATP-dependent protease La (LON) domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 1.20426875618254 | bayes_pls_golite062009 |
| protein binding | 0.594610587848879 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 0.533622874557729 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.505301584684092 | bayes_pls_golite062009 |
| catalytic activity | 0.174240748624544 | bayes_pls_golite062009 |
|
Region A: Residues: [388-449] |
1 11 21 31 41 51
| | | | | |
1 FDRKSPVINA LTSEILKVFK EISQLNTMFR EQIATFSASI QSATTNIFEE PARLADFAAA 60
61 VS
|
| Detection Method: | |
| Confidence: | 7.54 |
| Match: | 1jqjC |
| Description: | delta subunit; delta subunit of DNA polymerase III, N-domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [450-581] |
1 11 21 31 41 51
| | | | | |
1 AGEEDELQDI LSSLNIEHRL EKSLLVLKKE LMNAELQNKI SKDVETKIQK RQREYYLMEQ 60
61 LKGIKRELGI DDGRDKLIDT YKERIKSLKL PDSVQKIFDD EITKLSTLET SMSEFGVIRN 120
121 YLDWLTSIPW GK
|
| Detection Method: | |
| Confidence: | 7.54 |
| Match: | 1jqjC |
| Description: | delta subunit; delta subunit of DNA polymerase III, N-domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [582-768] |
1 11 21 31 41 51
| | | | | |
1 HSKEQYSIPR AKKILDEDHY GMVDVKDRIL EFIAVGKLLG KVDGKIICFV GPPGVGKTSI 60
61 GKSIARALNR KFFRFSVGGM TDVAEIKGHR RTYIGALPGR VVQALKKCQT QNPLILIDEI 120
121 DKIGHGGIHG DPSAALLEVL DPEQNNSFLD NYLDIPIDLS KVLFVCTANS LETIPRPLLD 180
181 RMEVIEL
|
| Detection Method: | |
| Confidence: | 62.221849 |
| Match: | 1e32A_ |
| Description: | Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ribonuclease activity | 2.03745175432755 | bayes_pls_golite062009 |
| nuclease activity | 1.83032641679211 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.38482286547386 | bayes_pls_golite062009 |
| hydrolase activity | 1.18773479836745 | bayes_pls_golite062009 |
| 3'-5'-exoribonuclease activity | 1.16726450662143 | bayes_pls_golite062009 |
| exoribonuclease activity | 1.1604717842042 | bayes_pls_golite062009 |
| structural molecule activity | 1.14918348313691 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 1.13566902804592 | bayes_pls_golite062009 |
| ATP-dependent peptidase activity | 0.99253423929971 | bayes_pls_golite062009 |
| binding | 0.923114523007774 | bayes_pls_golite062009 |
| catalytic activity | 0.878454819018611 | bayes_pls_golite062009 |
| peptidase activity | 0.46678532223973 | bayes_pls_golite062009 |
| protein binding | 0.398523921130957 | bayes_pls_golite062009 |
| endopeptidase activity | 0.227419965943609 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 0.161393552073973 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.0709817198603016 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 6.9430052008157E-5 | bayes_pls_golite062009 |
|
Region A: Residues: [769-890] |
1 11 21 31 41 51
| | | | | |
1 TGYVAEDKVK IAEQYLVPSA KKSAGLENSH VDMTEDAITA LMKYYCRESG VRNLKKHIEK 60
61 IYRKAALQVV KKLSIEDSPT SSADSKPKES VSSEEKAENN AKSSSEKTKD NNSEKTSDDI 120
121 EA
|
| Detection Method: | |
| Confidence: | 62.221849 |
| Match: | 1e32A_ |
| Description: | Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [891-988] |
1 11 21 31 41 51
| | | | | |
1 LKTSEKINVS ISQKNLKDYV GPPVYTTDRL YETTPPGVVM GLAWTNMGGC SLYVESVLEQ 60
61 PLHNCKHPTF ERTGQLGDVM KESSRLAYSF AKMYLAQK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.705 | 0.049 | response to heat | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.865 | N/A | N/A | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.849 | N/A | N/A | c.51.2 | TolB, N-terminal domain |
| View | Download | 0.607 | N/A | N/A | d.105.1 | Clathrin adaptor appendage, alpha and beta chain-specific domain |
| View | Download | 0.585 | N/A | N/A | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.583 | N/A | N/A | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.576 | N/A | N/A | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.556 | N/A | N/A | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.555 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.554 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.547 | N/A | N/A | b.11.1 | gamma-Crystallin-like |
| View | Download | 0.541 | N/A | N/A | d.204.1 | Ribosome binding protein Y (YfiA homologue) |
| View | Download | 0.538 | N/A | N/A | d.202.1 | Transcription factor NusA, N-terminal domain |
| View | Download | 0.536 | N/A | N/A | d.50.1 | dsRNA-binding domain-like |
| View | Download | 0.535 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.484 | N/A | N/A | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.451 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.446 | N/A | N/A | b.1.1 | Immunoglobulin |
| View | Download | 0.436 | N/A | N/A | b.1.12 | Purple acid phosphatase, N-terminal domain |
| View | Download | 0.431 | N/A | N/A | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.423 | N/A | N/A | b.97.1 | Anemone pore-forming cytolysin |
| View | Download | 0.413 | N/A | N/A | d.81.1 | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |
| View | Download | 0.399 | N/A | N/A | c.51.3 | B12-dependend dehydatases associated subunit |
| View | Download | 0.394 | N/A | N/A | d.17.2 | Copper amine oxidase, domains 1 and 2 |
| View | Download | 0.381 | N/A | N/A | c.23.12 | Formate/glycerate dehydrogenase catalytic domain-like |
| View | Download | 0.379 | N/A | N/A | d.52.5 | Probable GTPase Der, C-terminal domain |
| View | Download | 0.371 | N/A | N/A | b.43.4 | Riboflavin synthase domain-like |
| View | Download | 0.368 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.366 | N/A | N/A | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.360 | N/A | N/A | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.350 | N/A | N/A | b.61.3 | D-aminopeptidase, middle and C-terminal domains |
| View | Download | 0.343 | N/A | N/A | a.83.1 | Guanido kinase N-terminal domain |
| View | Download | 0.328 | N/A | N/A | d.58.19 | Bacterial exopeptidase dimerisation domain |
| View | Download | 0.325 | N/A | N/A | d.41.2 | Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain |
| View | Download | 0.309 | N/A | N/A | d.199.1 | DNA-binding C-terminal domain of the transcription factor MotA |
| View | Download | 0.308 | N/A | N/A | d.175.1 | Penicillin binding protein dimerisation domain |
| View | Download | 0.304 | N/A | N/A | c.52.1 | Restriction endonuclease-like |
| View | Download | 0.304 | N/A | N/A | d.1.1 | Microbial ribonucleases |
| View | Download | 0.304 | N/A | N/A | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.293 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.293 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.290 | N/A | N/A | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.281 | N/A | N/A | d.198.1 | Type III secretory system chaperone |
| View | Download | 0.273 | N/A | N/A | d.52.6 | BolA-like |
| View | Download | 0.258 | N/A | N/A | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.257 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.257 | N/A | N/A | b.61.1 | Avidin/streptavidin |
| View | Download | 0.252 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.247 | N/A | N/A | d.52.4 | YhbC-like, N-terminal domain |
| View | Download | 0.246 | N/A | N/A | c.20.1 | Initiation factor IF2/eIF5b, domain 3 |
| View | Download | 0.241 | N/A | N/A | b.52.2 | ADC-like |
| View | Download | 0.233 | N/A | N/A | d.17.4 | NTF2-like |
| View | Download | 0.232 | N/A | N/A | d.9.2 | Description not found. |
| View | Download | 0.228 | N/A | N/A | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.225 | N/A | N/A | b.4.1 | HSP40/DnaJ peptide-binding domain |
| View | Download | 0.221 | N/A | N/A | a.60.1 | SAM/Pointed domain |
| View | Download | 0.221 | N/A | N/A | d.233.1 | Inhibitor of vertebrate lysozyme, Ivy |
| View | Download | 0.220 | N/A | N/A | d.82.2 | Frataxin-like |
| View | Download | 0.218 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.216 | N/A | N/A | b.7.1 | C2 domain (Calcium/lipid-binding domain, CaLB) |
| View | Download | 0.208 | N/A | N/A | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
|
Region A: Residues: [989-1133] |
1 11 21 31 41 51
| | | | | |
1 FPENRFFEKA SIHLHCPEGA TPKDGPSAGV TMATSFLSLA LNKSIDPTVA MTGELTLTGK 60
61 VLRIGGLREK AVAAKRSGAK TIIFPKDNLN DWEELPDNVK EGLEPLAADW YNDIFQKLFK 120
121 DVNTKEGNSV WKAEFEILDA KKEKD
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.763 | 0.539 | response to heat | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.766 | 0.099 | response to heat | c.26.1 | Nucleotidylyl transferase |
| View | Download | 0.765 | 0.066 | response to heat | c.23.1 | CheY-like |
| View | Download | 0.727 | N/A | N/A | c.55.5 | MTH1175-like |
| View | Download | 0.552 | N/A | N/A | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.534 | N/A | N/A | c.30.1 | PreATP-grasp domain |
| View | Download | 0.523 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.516 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.514 | N/A | N/A | d.58.39 | Glutamyl tRNA-reductase catalytic, N-terminal domain |
| View | Download | 0.507 | N/A | N/A | c.26.2 | Adenine nucleotide alpha hydrolases-like |
| View | Download | 0.470 | N/A | N/A | c.98.2 | HPr kinase/phoshatase HprK N-terminal domain |
| View | Download | 0.462 | N/A | N/A | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.447 | N/A | N/A | c.23.12 | Formate/glycerate dehydrogenase catalytic domain-like |
| View | Download | 0.446 | N/A | N/A | c.23.6 | Cobalamin (vitamin B12)-binding domain |
| View | Download | 0.445 | N/A | N/A | c.53.1 | Resolvase-like |
| View | Download | 0.444 | N/A | N/A | d.131.1 | DNA clamp |
| View | Download | 0.442 | N/A | N/A | c.1.17 | Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain |
| View | Download | 0.441 | N/A | N/A | c.44.2 | Enzyme IIB-cellobiose |
| View | Download | 0.431 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.430 | N/A | N/A | d.202.1 | Transcription factor NusA, N-terminal domain |
| View | Download | 0.426 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.426 | N/A | N/A | c.23.3 | Hypothetical protein MTH538 |
| View | Download | 0.424 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.420 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.411 | N/A | N/A | c.23.14 | Nucleoside 2-deoxyribosyltransferase |
| View | Download | 0.411 | N/A | N/A | c.52.1 | Restriction endonuclease-like |
| View | Download | 0.407 | N/A | N/A | c.23.13 | Type II 3-dehydroquinate dehydratase |
| View | Download | 0.407 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.406 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.392 | N/A | N/A | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
| View | Download | 0.391 | N/A | N/A | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.386 | N/A | N/A | c.97.1 | Cytidine deaminase-like |
| View | Download | 0.386 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.385 | N/A | N/A | d.44.1 | Fe,Mn superoxide dismutase (SOD), C-terminal domain |
| View | Download | 0.377 | N/A | N/A | d.122.1 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| View | Download | 0.374 | N/A | N/A | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.374 | N/A | N/A | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.366 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.357 | N/A | N/A | c.95.1 | Thiolase-like |
| View | Download | 0.356 | N/A | N/A | c.61.1 | PRTase-like |
| View | Download | 0.354 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.352 | N/A | N/A | c.95.1 | Thiolase-like |
| View | Download | 0.341 | N/A | N/A | c.84.1 | Phosphoglucomutase, first 3 domains |
| View | Download | 0.338 | N/A | N/A | c.30.1 | PreATP-grasp domain |
| View | Download | 0.338 | N/A | N/A | c.54.1 | IIA domain of mannose transporter, IIA-Man |
| View | Download | 0.329 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.328 | N/A | N/A | c.66.1 | S-adenosyl-L-methionine-dependent methyltransferases |
| View | Download | 0.326 | N/A | N/A | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.325 | N/A | N/A | d.79.3 | L30e-like |
| View | Download | 0.324 | N/A | N/A | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.320 | N/A | N/A | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
| View | Download | 0.306 | N/A | N/A | c.24.1 | Methylglyoxal synthase-like |
| View | Download | 0.295 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.293 | N/A | N/A | c.23.16 | Class I glutamine amidotransferase-like |
| View | Download | 0.289 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.279 | N/A | N/A | c.23.6 | Cobalamin (vitamin B12)-binding domain |
| View | Download | 0.274 | N/A | N/A | d.189.1 | PX domain |
| View | Download | 0.272 | N/A | N/A | d.79.1 | YjgF-like |
| View | Download | 0.271 | N/A | N/A | c.98.1 | MurE/MurF N-terminal domain |
| View | Download | 0.260 | N/A | N/A | d.79.3 | L30e-like |
| View | Download | 0.260 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.258 | N/A | N/A | c.1.10 | Aldolase |
| View | Download | 0.253 | N/A | N/A | c.108.1 | HAD-like |
| View | Download | 0.251 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.238 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.232 | N/A | N/A | c.23.9 | Cutinase-like |
| View | Download | 0.224 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.222 | N/A | N/A | d.79.1 | YjgF-like |
| View | Download | 0.221 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.216 | N/A | N/A | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.215 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.208 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.208 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
