Protein Overview: LONM_YEAST

General Information:
Name(s) found:	LONM_YEAST [Swiss-Prot]
Description(s) found:	Lon protease homolog, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PIM1 PE=1 SV=2 [Swiss-Prot]
Organism:	Saccharomyces cerevisiae S288c
Length:	1133 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRTRTTKTL STVARTTRAI QYYRSIAKTA AVSQRRFAST LTVRDVENIK PSHIIKSPTW  60
   61 QEFQHQLKDP RYMEHFAQLD AQFARHFMAT NSGKSILAKD DSTSQKKDED VKIVPDEKDT 120
  121 DNDVEPTRDD EIVNKDQEGE ASKNSRSSAS GGGQSSSSRS DSGDGSSKQK PPKDVPEVYP 180
  181 QMLALPIARR PLFPGFYKAV VISDERVMKA IKEMLDRQQP YIGAFMLKNS EEDTDVITDK 240
  241 NDVYDVGVLA QITSAFPSKD EKTGTETMTA LLYPHRRIKI DELFPPNEEK EKSKEQAKDT 300
  301 DTETTVVEDA NNPEDQESTS PATPKLEDIV VERIPDSELQ HHKRVEATEE ESEELDDIQE 360
  361 GEDINPTEFL KNYNVSLVNV LNLEDEPFDR KSPVINALTS EILKVFKEIS QLNTMFREQI 420
  421 ATFSASIQSA TTNIFEEPAR LADFAAAVSA GEEDELQDIL SSLNIEHRLE KSLLVLKKEL 480
  481 MNAELQNKIS KDVETKIQKR QREYYLMEQL KGIKRELGID DGRDKLIDTY KERIKSLKLP 540
  541 DSVQKIFDDE ITKLSTLETS MSEFGVIRNY LDWLTSIPWG KHSKEQYSIP RAKKILDEDH 600
  601 YGMVDVKDRI LEFIAVGKLL GKVDGKIICF VGPPGVGKTS IGKSIARALN RKFFRFSVGG 660
  661 MTDVAEIKGH RRTYIGALPG RVVQALKKCQ TQNPLILIDE IDKIGHGGIH GDPSAALLEV 720
  721 LDPEQNNSFL DNYLDIPIDL SKVLFVCTAN SLETIPRPLL DRMEVIELTG YVAEDKVKIA 780
  781 EQYLVPSAKK SAGLENSHVD MTEDAITALM KYYCRESGVR NLKKHIEKIY RKAALQVVKK 840
  841 LSIEDSPTSS ADSKPKESVS SEEKAENNAK SSSEKTKDNN SEKTSDDIEA LKTSEKINVS 900
  901 ISQKNLKDYV GPPVYTTDRL YETTPPGVVM GLAWTNMGGC SLYVESVLEQ PLHNCKHPTF 960
  961 ERTGQLGDVM KESSRLAYSF AKMYLAQKFP ENRFFEKASI HLHCPEGATP KDGPSAGVTM1020
 1021 ATSFLSLALN KSIDPTVAMT GELTLTGKVL RIGGLREKAV AAKRSGAKTI IFPKDNLNDW1080
 1081 EELPDNVKEG LEPLAADWYN DIFQKLFKDV NTKEGNSVWK AEFEILDAKK EKD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..155]	deduced	N/A	No confident structure predictions are available.
2	View Details	[156..387]	Pfam	71.744727	ATP-dependent protease La (LON) domain No confident structure predictions are available.
3	View Details	[388..449]	ORFEUS	7.54	delta subunit; delta subunit of DNA polymerase III, N-domain
4	View Details	[450..581]	ORFEUS	7.54	delta subunit; delta subunit of DNA polymerase III, N-domain
5	View Details	[582..768]	PSI-BLAST	62.221849	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
6	View Details	[769..890]	PSI-BLAST	62.221849	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
7	View Details	[891..988]	MSA	2.234996	View MSA. Confident ab initio structure predictions are available.
8	View Details	[989..1133]	MSA	27.136997	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
binding	1.20426875618254	bayes_pls_golite062009
protein binding	0.594610587848879	bayes_pls_golite062009
ubiquitin-protein ligase activity	0.533622874557729	bayes_pls_golite062009
small conjugating protein ligase activity	0.505301584684092	bayes_pls_golite062009
catalytic activity	0.174240748624544	bayes_pls_golite062009

3

No functions predicted.

4

No functions predicted.

5

Term	Confidence	Notes
ribonuclease activity	2.03745175432755	bayes_pls_golite062009
nuclease activity	1.83032641679211	bayes_pls_golite062009
structural constituent of ribosome	1.38482286547386	bayes_pls_golite062009
hydrolase activity	1.18773479836745	bayes_pls_golite062009
3'-5'-exoribonuclease activity	1.16726450662143	bayes_pls_golite062009
exoribonuclease activity	1.1604717842042	bayes_pls_golite062009
structural molecule activity	1.14918348313691	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	1.13566902804592	bayes_pls_golite062009
ATP-dependent peptidase activity	0.99253423929971	bayes_pls_golite062009
binding	0.923114523007774	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
peptidase activity	0.46678532223973	bayes_pls_golite062009
protein binding	0.398523921130957	bayes_pls_golite062009
endopeptidase activity	0.227419965943609	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.161393552073973	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.0709817198603016	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	6.9430052008157E-5	bayes_pls_golite062009

6

No functions predicted.

7

No functions predicted.

8

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.78

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle