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View Structure Prediction Details

Protein: CE38543
Organism: Caenorhabditis elegans
Length: 579 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE38543.

Description E-value Query
Range
Subject
Range
CE33169 - status:Partially_confirmed UniProt:Q86S22 protein_id:AAO21390.1
523.0 [0..1] [579..1]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLPSILLIF GAFFGFLGAI HNTDDNAGYH NFKLIRINPE TEGSVKYLRS LYEDPSPYEL  60
   61 DFWQPPTNIG AIVDLTVAPA DAPRFVKDLE SKKISYIVAV NDLSKAIENE RGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 112.0
Match: 1ayeA
Description: HUMAN PROCARBOXYPEPTIDASE A2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [114-220]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKFYNPVAGF AYDKYNSLEE IQTEMKRLKK EYPTMITLID IGQSHENRTL LVMKITGKRN  60
   61 PLGSKISMWI DAGIHAREWI APATAMYIAH ELLLGYENDA TVAKLMD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1cpbA
Description: STRUCTURE OF CARBOXYPEPTIDASE B AT 2.8 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [221-439]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HIDFYILPVM NPDGYEYSRE KNRMWRKNRS PAKCARQTFS TVCCSGVDLN RNFDWFWAST  60
   61 GSSSDPCHDT YHGSAAFSEP ESQAVRDFLE QNTPEAFISL HSYSQMWLIP YGHRKQSYPQ 120
  121 DYHTGLRPLA LRATKALYEL YGTKYQVGTG ADLMYEASGG SHDWAKGQLK VPYAYLIELR 180
  181 PKNTMMGHGF LLPEREIVPT GLETFESIKV VADELVAQF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.0
Match: 1cpbB
Description: STRUCTURE OF CARBOXYPEPTIDASE B AT 2.8 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.786910294594 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.40766568731738 bayes_pls_golite062009
hydrolase activity 4.23257784904124 bayes_pls_golite062009
exopeptidase activity 3.28577934113028 bayes_pls_golite062009
metallopeptidase activity 2.76103081380105 bayes_pls_golite062009
carboxypeptidase activity 2.63658263814587 bayes_pls_golite062009
metalloexopeptidase activity 1.76058821499096 bayes_pls_golite062009
metallocarboxypeptidase activity 1.56827526553175 bayes_pls_golite062009
catalytic activity 1.3989281287879 bayes_pls_golite062009
binding 1.13031326446259 bayes_pls_golite062009
endopeptidase activity 0.910234727191613 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 0.723243947871592 bayes_pls_golite062009
serine hydrolase activity 0.596149133958797 bayes_pls_golite062009
serine-type peptidase activity 0.578572340123331 bayes_pls_golite062009
nucleic acid binding 0.454707207494165 bayes_pls_golite062009
transcription regulator activity 0.273337363793137 bayes_pls_golite062009
DNA binding 0.115087846898245 bayes_pls_golite062009
aminopeptidase activity 0.0966237570696103 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [440-579]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEPVIRAKLT TTTKPAIPPY RRGYSIIDTT TMEPVDEITQ KPTEAPTTEE PTTTTTEEPT  60
   61 TPEASTSSET STTENSEPNQ KTSTPVAPEA STVEEETITP IKCVDYGDYC RLWGVLQLCY 120
  121 RDQVSKLCPK TCDSRCSFSV 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.55
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle