| Protein: | cng-3 |
| Organism: | Caenorhabditis elegans |
| Length: | 626 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cng-3.
| Description | E-value | Query Range |
Subject Range |
|
|
333.0 | [0..5] | [595..205] |
|
Region A: Residues: [1-355] |
1 11 21 31 41 51
| | | | | |
1 MSTHSAQKLP NLHERKRRMS KKPDDDDLIP QHFEYENQYE KWRAANPRIE YDFSVDESGY 60
61 IYWIWTFFVV CGCLYNIIVL SVLAFENIRY AYIEKILPIN IAFDTVFLFD IILRSMLSFY 120
121 EDGVLITSFS ETWRHYVHSF YFAIDLLAIF PFDYLLIRKT SAAFCRLNRF LKIYRIANFI 180
181 AQSYGKLTQV TISLSKIFTA CFLLFHVNAC VFYIISVNSD TSSWDGVNAT FDDDEYLPWP 240
241 YTPEKITDAY FVGCDGRTDC YNPYFYYDEA REDHLVELYH FWRTDNRTHI YNFSQFTKEY 300
301 TLSMYWSAMT MTTLGEQPAP NTSLQNAFEI VNTLAGLLLF AVIMGSIGDL VANAN
|
| Detection Method: |  |
| Confidence: | 5.59 |
| Match: | 2a0lA |
| Description: | Crystal structure of KvAP-33H1 Fv complex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cation channel activity | 8.8271544979352 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 8.821528894161 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 8.74133052120115 | bayes_pls_golite062009 |
| ion channel activity | 8.5319589047463 | bayes_pls_golite062009 |
| gated channel activity | 8.44554798975713 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 8.43463411234305 | bayes_pls_golite062009 |
| voltage-gated channel activity | 8.4117395754193 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 8.36000486601638 | bayes_pls_golite062009 |
| channel activity | 8.32023913192244 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 8.32023913192244 | bayes_pls_golite062009 |
| substrate-specific channel activity | 8.30986502722514 | bayes_pls_golite062009 |
| potassium channel activity | 8.23401095904851 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 5.43467612453479 | bayes_pls_golite062009 |
| ligand-gated channel activity | 5.43467612453479 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 4.88789838906314 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 4.80939024913503 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 4.43208330555032 | bayes_pls_golite062009 |
| transporter activity | 2.77619896060397 | bayes_pls_golite062009 |
| inward rectifier potassium channel activity | 2.77094691956851 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.65613366364107 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.60593795082679 | bayes_pls_golite062009 |
|
Region A: Residues: [356-567] |
1 11 21 31 41 51
| | | | | |
1 AVKTFWQTLM DGLKQYMTYR NLNERLQTKV LKYCEYEMAE ETIMKEHEVR DELPAKLYGH 60
61 VTTSIIGASL VRSPLFRASE RSFLNDISQL LEPHYFCPGD VVIEKGQLCS SMFIIVCGQM 120
121 VEITEDNEID HFEGEILGDV NLIWFNNHLN HNRHQHNVIS SAFSQIHMLS RDDFFKVLSS 180
181 YDPKLKRRLC DVAFYLQRQR GELDDKKRCL SE
|
| Detection Method: | |
| Confidence: | 27.522879 |
| Match: | 1q3eA |
| Description: | HCN2J 443-645 in the presence of cGMP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cyclic nucleotide-gated ion channel activity | 10.1422916734545 | bayes_pls_golite062009 |
| intracellular cyclic nucleotide activated cation channel activity | 10.1422916734545 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 9.72053268940283 | bayes_pls_golite062009 |
| cation channel activity | 9.48749374439976 | bayes_pls_golite062009 |
| ion channel activity | 9.4846197809463 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 9.3929063879608 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 9.25176207085973 | bayes_pls_golite062009 |
| channel activity | 9.25176207085973 | bayes_pls_golite062009 |
| substrate-specific channel activity | 9.2472549851376 | bayes_pls_golite062009 |
| intracellular cGMP activated cation channel activity | 9.19973076787954 | bayes_pls_golite062009 |
| gated channel activity | 9.19042473454294 | bayes_pls_golite062009 |
| cGMP binding | 7.7575871125398 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| ligand-gated channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| cyclic nucleotide binding | 7.37322432929433 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 6.57272328088253 | bayes_pls_golite062009 |
| voltage-gated channel activity | 6.54930851487319 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 5.54400173845933 | bayes_pls_golite062009 |
| GMP binding | 5.49455172024846 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 5.34760703274696 | bayes_pls_golite062009 |
| potassium channel activity | 5.29889968906368 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 5.1138025954757 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 4.96516802098805 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 4.52895684111035 | bayes_pls_golite062009 |
| intracellular cAMP activated cation channel activity | 3.95109938608832 | bayes_pls_golite062009 |
| transporter activity | 3.30740141256752 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 3.24402760485462 | bayes_pls_golite062009 |
| transmembrane transporter activity | 3.22443361822344 | bayes_pls_golite062009 |
| molecular transducer activity | 1.7487659479534 | bayes_pls_golite062009 |
| signal transducer activity | 1.7487659479534 | bayes_pls_golite062009 |
| binding | 1.59096092728475 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.30878085449184 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.839610030740937 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.815055562928958 | bayes_pls_golite062009 |
| protein binding | 0.81302068072988 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.755486819364628 | bayes_pls_golite062009 |
|
Region A: Residues: [568-626] |
1 11 21 31 41 51
| | | | | |
1 NEDIESNLKR LAIDTLELHD KMTEMEEEFW DFSATAKRKL FESEMVVCDL LNNSQRRSR
|
| Detection Method: | |
| Confidence: | 14.522879 |
| Match: | 2gauA |
| Description: | No description for 2gauA was found. |
| Term | Confidence | Notes |
| binding | 2.88885372623841 | bayes_pls_golite062009 |
| nucleic acid binding | 2.57662935644785 | bayes_pls_golite062009 |
| DNA binding | 2.25550504100742 | bayes_pls_golite062009 |
| transcription factor activity | 1.64588582179037 | bayes_pls_golite062009 |
| signal transducer activity | 1.42015496657117 | bayes_pls_golite062009 |
| molecular transducer activity | 1.42015496657117 | bayes_pls_golite062009 |
| transcription regulator activity | 0.99422680194924 | bayes_pls_golite062009 |
| protein binding | 0.753698599635855 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.358723864160071 | bayes_pls_golite062009 |
| transcription activator activity | 0.182501400838027 | bayes_pls_golite062009 |
| transcription repressor activity | 0.0996090941687185 | bayes_pls_golite062009 |
