YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|15597000, gi\|...
Organism:	Pseudomonas aeruginosa PAO1
Length:	798 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|15597000, gi|....

Description	E-value	Query Range	Subject Range
gi\|82946730, gi\|... - gi\|83311889\|ref\|YP_422153.1\| ATP-dependent Lon protease [Magnetospirillum magneticum AMB-1], gi\|8294...	0.0	[5..792]	[8..795]
gi\|88920619, gi\|... - gi\|88940588\|ref\|ZP_01146023.1\| ATP-dependent protease La [Acidiphilium cryptum JF-5], gi\|88920619\|gb...	0.0	[5..796]	[21..812]
gi\|113875484, gi... - gi\|150396097\|ref\|YP_001326564.1\| ATP-dependent protease La [Sinorhizobium medicae WSM419], gi\|150027...	0.0	[2..798]	[9..806]
gi\|116049753, gi... - gi\|116049753\|ref\|YP_791440.1\| Lon protease [Pseudomonas aeruginosa UCBPP-PA14], gi\|115584974\|gb\|ABJ1...	0.0	[1..798]	[1..798]
LON_RHIME - ATP-dependent protease La OS=Rhizobium meliloti GN=lon PE=3 SV=2 LON_RHIME - Lon protease OS=Rhizobium meliloti (strain 1021) GN=lon PE=3 SV=2	0.0	[2..798]	[9..806]
gi\|114316143, gi... - gi\|114327969\|ref\|YP_745126.1\| ATP-dependent endopeptidase Lon [Granulibacter bethesdensis CGDNIH1], ...	0.0	[2..792]	[15..805]
gi\|70731344, gi\|... - gi\|70731344\|ref\|YP_261085.1\| ATP-dependent protease La [Pseudomonas fluorescens Pf-5], gi\|68345643\|g... gi\|7644385 - gi\|7644385\|gb\|AAF65564.1\|AF250140_1 protease Lon [Pseudomonas fluorescens]	0.0	[1..798]	[1..798]
gi\|6175841 - gi\|6175841\|gb\|AAF05300.1\|AF167159_1 Lon protease [Sinorhizobium meliloti]	0.0	[2..798]	[9..806]
gi\|114764586, gi... - gi\|114764586\|ref\|ZP_01443790.1\| ATP-dependent protease La [Roseovarius sp. HTCC2601], gi\|114542962\|g...	0.0	[1..798]	[1..801]
lon - lon ATP-dependent protease Lon 3349571:3352003 reverse MW:89360	0.0	[3..793]	[14..803]

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Predicted Domain #1

Region A:
Residues: [1-589]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTLVELPLL PLRDVVVYPH MVIPLFVGRE KSIEALEAAM TGDKQILLLA QKNPADDDPG  60
   61 EDGLYRMGTV ATVLQLLKLP DGTVKVLVEG EQRGQVERFI EEEGHIRAAV QAIDDANVGE 120
  121 REAEVFTRSL LSQFEQYVQL GKKVPAEVLS SLNSIDEPSR LVDTMAAHMA LKIEQKQDIL 180
  181 EITDLSSRVE HVLALLDAEI DLLQVEKRIR GRVKKQMERS QREYYLNEQM KAIQKELGDI 240
  241 DEGHNEVEEL KKRIDAAGLT KEAHTKATAE LNKLKQMSPM SAEATVVRSY IDWLLNVPWK 300
  301 AESKVRHDLA KAEDILDADH YGLEEVKERI LEYLAVQKRV KKLKGPVLCL VGPPGVGKTS 360
  361 LAESIARATN RKFVRMALGG VRDEAEIRGH RRTYIGSMPG RLIQKMTKVG VRNPLFLLDE 420
  421 IDKMGSDMRG DPASALLEVL DPEQNHNFND HYLEVDYDLS DVMFLCTANS MNIPAPLLDR 480
  481 MEVIRLPGYT EDEKVNIAAK YLIPKQVQAN GLKKGELTFE EGALRDIIRY YTREAGVRSL 540
  541 ERQIAKVCRK AVKEHAKLKR IQAVVSSETL ENYLGVRKFR YGLAEQQDQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	90.0
Match:	1qvrA
Description:	Crystal Structure Analysis of ClpB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleoside-triphosphatase activity	2.62748401933955	bayes_pls_golite062009
pyrophosphatase activity	2.55282098898104	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.5316131833172	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.53035702378505	bayes_pls_golite062009
binding	2.4974940028864	bayes_pls_golite062009
hydrolase activity	2.18454736627863	bayes_pls_golite062009
ATPase activity	2.04651885449197	bayes_pls_golite062009
ATPase activity, coupled	1.87142752786895	bayes_pls_golite062009
nucleic acid binding	1.41477043612798	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
DNA binding	0.734219822349235	bayes_pls_golite062009
motor activity	0.70874549510465	bayes_pls_golite062009
guanyl nucleotide binding	0.640772201693186	bayes_pls_golite062009
guanyl ribonucleotide binding	0.63468044350616	bayes_pls_golite062009
GTP binding	0.621689261700018	bayes_pls_golite062009
transcription regulator activity	0.613020689836258	bayes_pls_golite062009
substrate-specific transporter activity	0.464456497491373	bayes_pls_golite062009
GTPase activity	0.437665353870877	bayes_pls_golite062009
active transmembrane transporter activity	0.434775387083003	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
transporter activity	0.39890191703346	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
primary active transmembrane transporter activity	0.294474570607914	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.282352478532746	bayes_pls_golite062009
transmembrane transporter activity	0.22939561735194	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.220608508617331	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.219533217661421	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.219157471322311	bayes_pls_golite062009
protein binding	0.193768631623192	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.0756212238097211	bayes_pls_golite062009
protein transporter activity	0.0071389922757723	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [590-798]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGQVTGLAWT QVGGELLTIE AAVVPGKGQL TKTGSLGDVM AESITAALTV VRSRAQSLGI  60
   61 AADFHEKRDI HIHVPEGATP KDGPSAGIGM CTALVSAITQ IPVRADVAMT GEITLRGQVL 120
  121 AIGGLKEKLL AAHRGGIKTV IIPEENVRDL KEIPDNIKSD LVIKPVKWID EVLQIALQYA 180
  181 PEPLPDAAPE MVAKDEKREP DSKERISTH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.522879
Match:	1rr9A
Description:	Catalytic domain of E.coli Lon protease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.35244774225337	bayes_pls_golite062009
hydrolase activity	1.18773479836745	bayes_pls_golite062009
structural constituent of ribosome	1.18642233210148	bayes_pls_golite062009
nucleic acid binding	1.05662964529454	bayes_pls_golite062009
structural molecule activity	0.95398657951177	bayes_pls_golite062009
ribonuclease activity	0.927662190590087	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
transcription regulator activity	0.831274075251956	bayes_pls_golite062009
peptidase activity	0.46678532223973	bayes_pls_golite062009
DNA binding	0.445830226393056	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.345231097228971	bayes_pls_golite062009
exoribonuclease activity	0.343836551142441	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	0.321834241843501	bayes_pls_golite062009
pyrophosphatase activity	0.277818626067707	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.258012116925759	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.257636057176676	bayes_pls_golite062009
ATPase activity	0.256995590197315	bayes_pls_golite062009
protein binding	0.214066724623027	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.161393552073973	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: