YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29541088, gi\|...
Organism:	Coxiella burnetii RSA 493
Length:	269 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29541088, gi|....

Description	E-value	Query Range	Subject Range
gi\|23347774, gi\|... - gi\|23501838\|ref\|NP_697965.1\| amino acid ABC transporter, periplasmic amino acid-binding protein [Bru... gi\|163843223, gi... - gi\|163843223\|ref\|YP_001627627.1\| extracellular solute-binding protein [Brucella suis ATCC 23445], gi... gi\|161335722, gi... - gi\|161618911\|ref\|YP_001592798.1\| extracellular solute-binding protein [Brucella canis ATCC 23365], g... gi\|254704255 - gi\|254704255\|ref\|ZP_05166083.1\| extracellular solute-binding protein [Brucella suis bv. 3 str. 686] gi\|254701713 - gi\|254701713\|ref\|ZP_05163541.1\| extracellular solute-binding protein [Brucella suis bv. 5 str. 513]	222.0	[0..9]	[269..1]
gi\|238717579, gi... - gi\|77961132\|ref\|ZP_00824978.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p...	221.0	[0..1]	[269..1]
gi\|154706907, gi... - gi\|94491186\|ref\|ZP_01298403.1\| hypothetical protein CburD_01001729 [Coxiella burnetii Dugway 7E9-12]...	218.0	[0..1]	[269..1]
gi\|68348053, gi\|... - gi\|70733754\|ref\|YP_257394.1\| cystine transporter subunit [Pseudomonas fluorescens Pf-5], gi\|68348053...	218.0	[0..7]	[269..1]
gi\|28872292, gi\|... - gi\|28872292\|ref\|NP_794911.1\| cystine transporter subunit [Pseudomonas syringae pv. tomato str. DC300... tr\|Q87UW2\|Q87UW2... - Cystine ABC transporter, periplasmic cystine binding protein OS=Pseudomonas syringae pv. tomato (str... gi\|213925766, gi... - gi\|213969395\|ref\|ZP_03397532.1\| cystine ABC transporter, periplasmic cystine binding protein [Pseudo...	218.0	[0..7]	[269..1]
gi\|77979904 - gi\|77979904\|ref\|ZP_00835320.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p...	217.0	[0..1]	[269..1]
gi\|16122097, gi\|... - gi\|218928965\|ref\|YP_002346840.1\| cystine transporter subunit [Yersinia pestis CO92], gi\|16122097\|ref... gi\|166010832, gi... - gi\|166010832\|ref\|ZP_02231730.1\| cystine-binding periplasmic protein FliY [Yersinia pestis biovar Ant... gi\|165925949, gi... - gi\|165925949\|ref\|ZP_02221781.1\| cystine-binding periplasmic protein FliY [Yersinia pestis biovar Ori... gi\|167401164, gi... - gi\|167401164\|ref\|ZP_02306667.1\| cystine-binding periplasmic protein FliY [Yersinia pestis biovar Ant... gi\|166207832, gi... - gi\|166210652\|ref\|ZP_02236687.1\| cystine-binding periplasmic protein FliY [Yersinia pestis biovar Ant... gi\|167055180, gi... - gi\|167425781\|ref\|ZP_02317534.1\| cystine-binding periplasmic protein FliY [Yersinia pestis biovar Med... gi\|166961845, gi... - gi\|167420150\|ref\|ZP_02311903.1\| cystine-binding periplasmic protein FliY [Yersinia pestis biovar Ori... gi\|149292621, gi... - gi\|149366208\|ref\|ZP_01888243.1\| putative cystine-binding periplasmic protein [Yersinia pestis CA88-4... gi\|229701217, gi... - gi\|229896294\|ref\|ZP_04511464.1\| cystine transporter subunit; periplasmic-binding component of ABC su... gi\|165913394, gi... - gi\|89105430\|ref\|ZP_01177949.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p... gi\|229693568, gi... - gi\|229897231\|ref\|ZP_04512387.1\| cystine transporter subunit; periplasmic-binding component of ABC su... gi\|162353595, gi... - gi\|77635978\|ref\|ZP_00798056.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p... gi\|108779131, gi... - gi\|108807218\|ref\|YP_651134.1\| cystine transporter subunit [Yersinia pestis Antiqua], gi\|108779131\|gb... gi\|229897958, gi... - gi\|229897958\|ref\|ZP_04513109.1\| cystine transporter subunit; periplasmic-binding component of ABC su... gi\|117673858, gi... - gi\|77628915\|ref\|ZP_00791501.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p... gi\|229680258, gi... - gi\|229902811\|ref\|ZP_04517928.1\| cystine transporter subunit; periplasmic-binding component of ABC su... Q66BQ3\|Q66BQ3_YERPS - Putative cystine-binding periplasmic protein precursor - Yersinia pseudotuberculosis gi\|186895159, gi... - gi\|186895159\|ref\|YP_001872271.1\| cystine transporter subunit [Yersinia pseudotuberculosis PB1/+], gi... gi\|170024601, gi... - gi\|170024601\|ref\|YP_001721106.1\| cystine transporter subunit [Yersinia pseudotuberculosis YPIII], gi... gi\|22126343, gi\|... - gi\|22126343\|ref\|NP_669766.1\| cystine transporter subunit [Yersinia pestis KIM], gi\|21959325\|gb\|AAM86... gi\|25296340 - pir\|\|AC0225 probable cystine-binding periplasmic protein fliY [imported] - Yersinia pestis (strain C... gi\|51596053, gi\|... - gi\|51596053\|ref\|YP_070244.1\| cystine transporter subunit [Yersinia pseudotuberculosis IP 32953], gi\|... gi\|45441366, gi\|... - gi\|45441366\|ref\|NP_992905.1\| cystine transporter subunit [Yersinia pestis biovar Microtus str. 91001...	217.0	[0..7]	[269..1]
gi\|77957941 - gi\|77957941\|ref\|ZP_00821984.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p...	216.0	[0..7]	[269..1]
gi\|25296327 - pir\|\|E96946 periplasmic amino acid-binding protein [imported] - Clostridium acetobutylicum gi\|15023229, gi\|... - gi\|15893671\|ref\|NP_347020.1\| periplasmic amino acid-binding protein [Clostridium acetobutylicum ATCC...	216.0	[0..1]	[269..1]
gi\|7442310 - pir\|\|G69278 glutamine ABC transporter, periplasmic glutamine-binding protein (glnH) homolog - Archae... gi\|2650410, gi\|1... - gi\|2650410\|gb\|AAB91001.1\| glutamine ABC transporter, periplasmic glutamine-binding protein (glnH) [A...	216.0	[0..36]	[268..33]

Back

Predicted Domain #1

Region A:
Residues: [1-269]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKNNNRAVS RFFRWIPAFV RMTGTFYFVS CLFVSPVFAT DTIKFATEAT YPPYVYMGPS  60
   61 GQVEGFGADI VKAVCKQMQA VCTISNQPWD SLIPSLKLGK FDALFGGMNI TTARQKEVDF 120
  121 TDPYYTNSVS FIADKNTPLT LSKQGLKGKI IGVQGGTTFD SYLQDSFGNS ITIQRYPSEE 180
  181 DALMDLTSGR VDAVVGDTPL IKQWLKQNGR REYVLIGKPV NDPNYFGKGV GIAVKKGNQA 240
  241 LLLKLNKALA AIKANGVYAA IVQKYFGQE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.09691
Match:	1hpbP
Description:	Histidine-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
amino acid transmembrane transporter activity	2.89507136131183	bayes_pls_golite062009
amine transmembrane transporter activity	2.8505643526173	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	2.60409378812617	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.5640155514811	bayes_pls_golite062009
transporter activity	2.37767937786605	bayes_pls_golite062009
transmembrane transporter activity	2.14027396604232	bayes_pls_golite062009
active transmembrane transporter activity	1.98824826924235	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	1.92247368464925	bayes_pls_golite062009
primary active transmembrane transporter activity	1.91778402126342	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	1.91458600392598	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	1.91458600392598	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	1.91424996753266	bayes_pls_golite062009
amino acid-transporting ATPase activity	1.91134435333756	bayes_pls_golite062009
amine-transporting ATPase activity	1.88766300630813	bayes_pls_golite062009
ATPase activity, coupled	1.59154512845516	bayes_pls_golite062009
substrate-specific transporter activity	1.51716707550629	bayes_pls_golite062009
ATPase activity	1.44327228942016	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.36989838880058	bayes_pls_golite062009
pyrophosphatase activity	1.33033652028872	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.31993399326424	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.31926578892427	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.88733921737959	bayes_pls_golite062009
binding	0.841985743602294	bayes_pls_golite062009
polyamine transmembrane transporter activity	0.82443378583023	bayes_pls_golite062009
amino acid binding	0.61855649036974	bayes_pls_golite062009
polyamine-transporting ATPase activity	0.605434747769831	bayes_pls_golite062009
hydrolase activity	0.52200036125335	bayes_pls_golite062009
amine binding	0.48583609326514	bayes_pls_golite062009
catalytic activity	0.278324746769832	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: