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View Structure Prediction Details

Protein: ENSMMUG000000045...
Organism: Macaca mulatta
Length: 339 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENSMMUG000000045....

Description E-value Query
Range		 Subject
Range
gi|54696276 - gi|54696276|gb|AAV38510.1| RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) [synthetic construc...
 1.0E-84 [1..339] [1..339]
gi|197246432, gi... - gi|62645602|ref|XP_575211.1| PREDICTED: similar to DNA repair protein RAD51 homolog 1 [Rattus norveg...
 4.0E-84 [1..339] [1..339]
gi|397827 - gi|397827|dbj|BAA02962.1| HsRad51 [Homo sapiens]
 5.0E-84 [1..339] [1..339]
RAD51_CRIGR - DNA repair protein RAD51 homolog 1 OS=Cricetulus griseus GN=RAD51 PE=2 SV=1
 8.0E-84 [1..339] [1..339]
RAD51_BOVIN - DNA repair protein RAD51 homolog 1 OS=Bos taurus GN=RAD51 PE=2 SV=1
tr|M3WL72|M3WL72... - RAD51 recombinase OS=Felis catus GN=RAD51 PE=3 SV=1
 1.0E-83 [1..339] [1..339]
RAD51_CANLF - DNA repair protein RAD51 homolog 1 OS=Canis lupus familiaris GN=RAD51 PE=2 SV=1
 2.0E-83 [1..339] [1..339]
RAD51_MOUSE - DNA repair protein RAD51 homolog 1 OS=Mus musculus GN=Rad51 PE=1 SV=1
 2.0E-83 [1..339] [1..339]
RAD51_RABIT - DNA repair protein RAD51 homolog 1 OS=Oryctolagus cuniculus GN=RAD51 PE=2 SV=1
 4.0E-83 [1..339] [1..339]

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Predicted Domain #1
Region A:
Residues: [1-339] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMQMQLEAN ADTSVEEESF GPQPISRLEQ CGINANDVKK LEEAGFHTVE AVAYAPKKEL  60
   61 INIKGISEAK ADKILAEAAK LVPMGFTTAT EFHQRRSEII QITTGSKELD KLLQGGIETG 120
  121 SITEMFGEFR TGKTQICHTL AVTCQLPIDR GGGEGKAMYI DTEGTFRPER LLAVAERYGL 180
  181 SGSDVLDNVA YARAFNTDHQ TQLLYQASAM MVESRYALLI VDSATALYRT DYSGRGELSA 240
  241 RQMHLARFLR MLLRLADEFG VAVVITNQVV AQVDGAAMFA ADPKKPIGGN IIAHASTTRL 300
  301 YLRKGRGETR ICKIYDSPCL PEAEAMFAIN ADGVGDAKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.69897
Match: 1szpA
Description: A Crystal Structure of the Rad51 Filament
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
four-way junction helicase activity 6.34056703603795 bayes_pls_golite062009
DNA helicase activity 5.64236969551706 bayes_pls_golite062009
DNA clamp loader activity 3.22518920754305 bayes_pls_golite062009
protein-DNA loading ATPase activity 3.19273435123154 bayes_pls_golite062009
transporter activity 3.13325129560423 bayes_pls_golite062009
transmembrane transporter activity 2.92327745911863 bayes_pls_golite062009
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.69246499202248 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.66107861968804 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
bubble DNA binding 2.62179925837003 bayes_pls_golite062009
pyrophosphatase activity 2.61582393123755 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.59641929642359 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.59333672868803 bayes_pls_golite062009
hydrolase activity 2.55157966585974 bayes_pls_golite062009
nucleic acid binding 2.21184938313192 bayes_pls_golite062009
ATPase activity 2.11122403732968 bayes_pls_golite062009
double-strand/single-strand DNA junction binding 2.02697209084624 bayes_pls_golite062009
telomeric DNA binding 1.98044285764127 bayes_pls_golite062009
DNA binding 1.94055378599526 bayes_pls_golite062009
ATPase activity, coupled 1.8908019270286 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
transcription regulator activity 1.83584389083042 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
microtubule motor activity 1.6537049553461 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.37694050923424 bayes_pls_golite062009
motor activity 1.34881124154297 bayes_pls_golite062009
structure-specific DNA binding 1.2539059700735 bayes_pls_golite062009
protein transporter activity 1.25342367751911 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
double-stranded DNA binding 1.117585097627 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
substrate-specific transporter activity 0.97700154207756 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
single-stranded telomeric DNA binding 0.847538346941812 bayes_pls_golite062009
double-stranded telomeric DNA binding 0.75018916645383 bayes_pls_golite062009
transcription activator activity 0.739301862805678 bayes_pls_golite062009
purine nucleotide binding 0.725611289205392 bayes_pls_golite062009
nucleotide binding 0.717697610309727 bayes_pls_golite062009
purine ribonucleotide binding 0.713814218071151 bayes_pls_golite062009
ribonucleotide binding 0.713752628021599 bayes_pls_golite062009
transcription factor activity 0.697256579145077 bayes_pls_golite062009
guanyl nucleotide binding 0.656009904481476 bayes_pls_golite062009
guanyl ribonucleotide binding 0.64416740142962 bayes_pls_golite062009
GTP binding 0.643084645864898 bayes_pls_golite062009
single-stranded DNA binding 0.568457189190858 bayes_pls_golite062009
cytoskeletal protein binding 0.500462538667228 bayes_pls_golite062009
recombinase activity 0.45851158693664 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
RNA helicase activity 0.34746349346164 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
histone acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
centromeric DNA binding 0.322818640526369 bayes_pls_golite062009
mismatched DNA binding 0.31144582840038 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.30832907234141 bayes_pls_golite062009
RNA-dependent ATPase activity 0.29532978396745 bayes_pls_golite062009
structural constituent of ribosome 0.208665086324262 bayes_pls_golite062009
ATP binding 0.19169045543599 bayes_pls_golite062009
exodeoxyribonuclease V activity 0.185603938981231 bayes_pls_golite062009
adenyl ribonucleotide binding 0.165732470448462 bayes_pls_golite062009
adenyl nucleotide binding 0.162060759063149 bayes_pls_golite062009
active transmembrane transporter activity 0.114463153989353 bayes_pls_golite062009
microfilament motor activity 0.10236059675512 bayes_pls_golite062009
ion transmembrane transporter activity 0.081265446432119 bayes_pls_golite062009
3'-5' DNA helicase activity 0.0769112340058804 bayes_pls_golite062009
protein transmembrane transporter activity 0.0378638259240902 bayes_pls_golite062009
actin binding 0.00482938540552702 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle