YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254751190
Organism:	Bacillus anthracis str. Vollum
Length:	562 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254751190.

Description	E-value	Query Range	Subject Range
gi\|51978662, gi\|... - gi\|52145193\|ref\|YP_081637.1\| DNA polymerase III subunits gamma and tau [Bacillus cereus E33L], gi\|51...	0.0	[1..562]	[1..562]
gi\|49476694, gi\|... - gi\|49476694\|ref\|YP_034378.1\| DNA polymerase III subunits gamma and tau [Bacillus thuringiensis serov... gi\|228931525, gi... - gi\|228931525\|ref\|ZP_04094433.1\| DNA polymerase III subunit gamma/tau [Bacillus thuringiensis serovar...	0.0	[1..562]	[1..562]
gi\|42779101, gi\|... - gi\|42779101\|ref\|NP_976348.1\| DNA polymerase III subunits gamma and tau [Bacillus cereus ATCC 10987],... gi\|228589069, gi... - gi\|229194413\|ref\|ZP_04321218.1\| DNA polymerase III subunit gamma/tau [Bacillus cereus m1293], gi\|228...	0.0	[1..562]	[1..562]
gi\|163860228, gi... - gi\|89208558\|ref\|ZP_01187058.1\| AAA ATPase, central region [Bacillus weihenstephanensis KBAB4], gi\|89...	0.0	[1..562]	[1..562]
gi\|89203305, gi\|... - gi\|89203305\|ref\|ZP_01181986.1\| AAA ATPase, central region [Bacillus cereus subsp. cytotoxis NVH 391-...	0.0	[1..562]	[1..562]
gi\|228657923, gi... - gi\|229125539\|ref\|ZP_04254573.1\| DNA polymerase III subunit gamma/tau [Bacillus cereus BDRD-Cer4], gi... gi\|29893835, gi\|... - gi\|30018295\|ref\|NP_829926.1\| DNA polymerase III subunits gamma and tau [Bacillus cereus ATCC 14579],...	0.0	[1..562]	[1..562]
gi\|163119173, gi... - gi\|52783877\|ref\|YP_089706.1\| DNA polymerase III subunits gamma and tau [Bacillus licheniformis ATCC ...	1.0E-96	[1..562]	[1..566]
DPO3X_BACSU, DP3... - DNA polymerase III subunit gamma/tau OS=Bacillus subtilis GN=dnaX PE=3 SV=2, (P09122) DNA polymerase...	1.0E-94	[1..562]	[1..563]
gi\|2632286, gi\|1... - gi\|2632286\|emb\|CAB11795.1\| DNA polymerase III (gamma and tau subunits) [Bacillus subtilis subsp. sub... gi\|467409, gi\|58... - pir\|\|S13786 DNA-directed DNA polymerase (EC 2.7.7.7) III chain dnaX - Bacillus subtilis, gi\|580914\|...	1.0E-94	[1..562]	[1..563]
gi\|16415387, gi\|... - pir\|\|AF1788 DNA polymerase III (gamma and tau chains) homolog dnaX [imported] - Listeria innocua (st... gi\|16801912 - gi\|16801912\|ref\|NP_472180.1\| hypothetical protein lin2852 [Listeria innocua Clip11262]	1.0E-92	[1..562]	[1..579]

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Predicted Domain #1

Region A:
Residues: [1-419]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYQALYRTW RPQKFEDVVG QKHVTKTLQN ALLQEKVSHA YLFSGPRGTG KTTIAKVFAK  60
   61 AINCEHAPVA EPCNECPSCL GITQGSISDV LEIDAASNNG VDEIRDIRDK VKYAPSAVEY 120
  121 KVYIIDEVHM LSMGAFNALL KTLEEPPGHV IFILATTEPH KIPPTIISRC QRFEFRKISV 180
  181 NDIVERLSTV VTNEGTQVED EALQIVARAA EGGMRDALSL IDQAISYSDE RVTTEDVLAV 240
  241 TGSVSQQYLG NLVECIREND VSRALRIIDE MMGKGKDPVR FMEDFIYYYR DMLLYQTSPQ 300
  301 LEHMLERVMV DEQFRMLSEE MQPEVIYEII HTLSKGQQEM KWTNHPRIFL EVVMVQLCQQ 360
  361 FMMQANGADR LQAIMNRMQQ LEKELEQVKK NGVPVGVQQE VKETRAAPKP VRTGSMKIP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.045757
Match:	1xxiB
Description:	ADP Bound E. coli Clamp Loader Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA clamp loader activity	6.51495346697904	bayes_pls_golite062009
protein-DNA loading ATPase activity	6.40748863504898	bayes_pls_golite062009
DNA-directed DNA polymerase activity	6.09279996112705	bayes_pls_golite062009
DNA polymerase activity	6.04865791514294	bayes_pls_golite062009
nucleotidyltransferase activity	3.99580940620614	bayes_pls_golite062009
DNA-dependent ATPase activity	2.72462789867829	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
mismatched DNA binding	2.51625633651862	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.40352415448799	bayes_pls_golite062009
DNA helicase activity	2.2817164193758	bayes_pls_golite062009
pyrophosphatase activity	2.13284212711072	bayes_pls_golite062009
ATP-dependent DNA helicase activity	1.88455339138556	bayes_pls_golite062009
	1.85506769032946	bayes_pls_golite062009
helicase activity	1.70242731830224	bayes_pls_golite062009
guanine/thymine mispair binding	1.69026972999845	bayes_pls_golite062009
DNA insertion or deletion binding	1.68890613599528	bayes_pls_golite062009
RNA helicase activity	1.63960194106079	bayes_pls_golite062009
ATP-dependent RNA helicase activity	1.61735400124552	bayes_pls_golite062009
RNA-dependent ATPase activity	1.60404584546501	bayes_pls_golite062009
nucleic acid binding	1.49633029954726	bayes_pls_golite062009
structure-specific DNA binding	1.2539059700735	bayes_pls_golite062009
transferase activity	1.23626141560528	bayes_pls_golite062009
purine ribonucleotide binding	1.21658213854831	bayes_pls_golite062009
ribonucleotide binding	1.21652144153182	bayes_pls_golite062009
purine nucleotide binding	1.21571071905795	bayes_pls_golite062009
nucleotide binding	1.20347573865566	bayes_pls_golite062009
purine NTP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
ATP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
motor activity	1.14667913749579	bayes_pls_golite062009
microtubule motor activity	1.1277447806079	bayes_pls_golite062009
double-stranded DNA binding	1.117585097627	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
DNA binding	0.967303417236485	bayes_pls_golite062009
transcription regulator activity	0.748437190903548	bayes_pls_golite062009
single base insertion or deletion binding	0.629563765934841	bayes_pls_golite062009
single-stranded DNA binding	0.568457189190858	bayes_pls_golite062009
cytoskeletal protein binding	0.500462538667228	bayes_pls_golite062009
guanyl nucleotide binding	0.388587892299301	bayes_pls_golite062009
guanyl ribonucleotide binding	0.372638007722845	bayes_pls_golite062009
GTP binding	0.364508542344128	bayes_pls_golite062009
DNA strand annealing activity	0.283577486331079	bayes_pls_golite062009
protein binding	0.170837278876362	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.147579541298736	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.113504049290503	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.111293884322157	bayes_pls_golite062009
structural constituent of ribosome	0.089234257580272	bayes_pls_golite062009
GTPase activity	0.0742799394423282	bayes_pls_golite062009
lysine N-acetyltransferase activity	0.0320943071400439	bayes_pls_golite062009
histone acetyltransferase activity	0.0320943071400439	bayes_pls_golite062009
actin binding	0.00482938540552702	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [420-562]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGRVNEVLKQ AKRQDLEQLK AVWGELLGRL KAYNKVAFAV LLENSEPVAA SDDTYVLAFQ  60
   61 YEIHCKMASE NREAMDTVEQ ALFELLSKKL NMIAIPKSEW GKIREDFLKR EGGSSEESPE 120
  121 KKEDPLIEEA IKLVGQELIE IKE

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.28
Match:	2ayaA
Description:	No description for 2ayaA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: