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View Structure Prediction Details

Protein: gi|220955784, gi...
Organism: synthetic construct
Length: 682 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220955784, gi....

Description E-value Query
Range
Subject
Range
gi|6523177 - gi|6523177|emb|CAB62169.1| ARALAR 1 protein [Drosophila melanogaster]
499.0 [0..1] [682..1]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLTKSLPNS PSLLKRAGTE KLREVFLKYA SIQKNGEHYM TSEDFVRKFL GLFSESAFND  60
   61 ESVRLLANIA DTSKDGLISF SEFQAFEGLL CTPDALYRTA FQLFDRKGNG TVSYADFADV 120
  121 VQKTELHSKI PFSLDGPFIK RYFGDKKQRL INYAEFTQLL HDFHEEHAME AFRSKDPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.69897
Match: 2f2oA
Description: Structure of calmodulin bound to a calcineurin peptide: a new way of making an old binding mode
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [179-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTGFISPLDF QDIIVNVKRH LLTPGVRDNL VSVTEGHKVS FPYFIAFTSL LNNMELIKQV  60
   61 YLHATEGSRT DMITKDQILL AAQTMSQITP LEIDILFHLA GAVHQAGRID YSDLSNIAPE 120
  121 HYTKHMTHRL AEIKAVES

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.18
Match: 1hqvA
Description: Apoptosis-linked protein alg-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
calcium ion binding 3.3502343978768 bayes_pls_golite062009
binding 2.62940555587192 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.62465453278501 bayes_pls_golite062009
ion transmembrane transporter activity 2.58331384033974 bayes_pls_golite062009
cation transmembrane transporter activity 2.56450760908401 bayes_pls_golite062009
cytoskeletal protein binding 2.46558208549358 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.39219065596758 bayes_pls_golite062009
structural molecule activity 1.98487959981447 bayes_pls_golite062009
potassium channel activity 1.89216151100151 bayes_pls_golite062009
voltage-gated potassium channel activity 1.80063823023387 bayes_pls_golite062009
motor activity 1.68044193245645 bayes_pls_golite062009
cation channel activity 1.4950665324992 bayes_pls_golite062009
actin binding 1.42596573582079 bayes_pls_golite062009
molecular transducer activity 1.39455566984566 bayes_pls_golite062009
signal transducer activity 1.39455566984566 bayes_pls_golite062009
structural constituent of muscle 1.38543362753268 bayes_pls_golite062009
transcription regulator activity 1.24632772915948 bayes_pls_golite062009
transporter activity 1.18173318787461 bayes_pls_golite062009
protein binding 1.09433047543741 bayes_pls_golite062009
passive transmembrane transporter activity 1.06257290148275 bayes_pls_golite062009
channel activity 1.06257290148275 bayes_pls_golite062009
ion channel activity 1.04002358216664 bayes_pls_golite062009
ion binding 1.03987367434642 bayes_pls_golite062009
substrate-specific channel activity 1.03912277255945 bayes_pls_golite062009
metal ion binding 1.02345340724535 bayes_pls_golite062009
cation binding 1.02345340724535 bayes_pls_golite062009
voltage-gated cation channel activity 0.978447945241838 bayes_pls_golite062009
transmembrane transporter activity 0.967232199555998 bayes_pls_golite062009
voltage-gated ion channel activity 0.903772926548548 bayes_pls_golite062009
microfilament motor activity 0.896570410571443 bayes_pls_golite062009
voltage-gated channel activity 0.890153400390069 bayes_pls_golite062009
nucleic acid binding 0.889351626579486 bayes_pls_golite062009
gated channel activity 0.857277240351281 bayes_pls_golite062009
DNA binding 0.846946233549871 bayes_pls_golite062009
tubulin binding 0.812194607648073 bayes_pls_golite062009
amine transmembrane transporter activity 0.718077220370247 bayes_pls_golite062009
substrate-specific transporter activity 0.713088884599039 bayes_pls_golite062009
actin-dependent ATPase activity 0.633699364706973 bayes_pls_golite062009
microtubule binding 0.459835151828266 bayes_pls_golite062009
active transmembrane transporter activity 0.255162242356474 bayes_pls_golite062009
protein complex binding 0.229066577003238 bayes_pls_golite062009
0.184502455796377 bayes_pls_golite062009
myosin binding 0.180486266101886 bayes_pls_golite062009
channel regulator activity 0.165732133218208 bayes_pls_golite062009
transcription factor binding 0.0313595597352014 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.014511553141427 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.011612192141763 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [317-682]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PADRSAFIQV LESSYRFTLG SFAGAVGATV VYPIDLVKTR MQNQRAGSYI GEVAYRNSWD  60
   61 CFKKVVRHEG FMGLYRGLLP QLMGVAPEKA IKLTVNDLVR DKLTDKKGNI PTWAEVLAGG 120
  121 CAGASQVVFT NPLEIVKIRL QVAGEIASGS KIRAWSVVRE LGLFGLYKGA RACLLRDVPF 180
  181 SAIYFPTYAH TKAMMADKDG YNHPLTLLAA GAIAGVPAAS LVTPADVIKT RLQVVARSGQ 240
  241 TTYTGVWDAT KKIMAEEGPR AFWKGTAARV FRSSPQFGVT LVTYELLQRL FYVDFGGTQP 300
  301 KGSEAHKITT PLEQAAASVT TENVDHIGGY RAAVPLLAGV ESKFGLYLPR FGRGVTAASP 360
  361 STATGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.09691
Match: 1okcA
Description: structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle