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View Structure Prediction Details

Protein: gi|190405354
Organism: Saccharomyces cerevisiae RM11-1a
Length: 231 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190405354.

Description E-value Query
Range
Subject
Range
RU1C_YEAST - U1 small nuclear ribonucleoprotein C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHC...
gi|190405354 - gi|190405354|gb|EDV08621.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
YHC1 - Component of the U1 snRNP complex required for pre-mRNA splicing; putative ortholog of human U1C pro...
gi|151941002 - gi|151941002|gb|EDN59383.1| U1-C [Saccharomyces cerevisiae YJM789]
0.0 [1..231] [1..231]
gi|19577373 - gi|19577373|emb|CAD27755.1| putative sRNP [Anopheles gambiae]
5.0E-27 [1..61] [1..61]
RU1C_XENLA - U1 small nuclear ribonucleoprotein C OS=Xenopus laevis GN=snrpc PE=2 SV=1
1.0E-26 [1..61] [1..61]
gi|194040342 - gi|194040342|ref|XP_001928855.1| PREDICTED: similar to U1 snRNP-specific protein C [Sus scrofa]
RU1C_BOVIN - U1 small nuclear ribonucleoprotein C OS=Bos taurus GN=SNRPC PE=2 SV=2
RU1C_MACMU - U1 small nuclear ribonucleoprotein C OS=Macaca mulatta GN=SNRPC PE=3 SV=1
RU1C_CANLF - U1 small nuclear ribonucleoprotein C OS=Canis lupus familiaris GN=SNRPC PE=3 SV=1
gi|149732134 - gi|149732134|ref|XP_001498478.1| PREDICTED: similar to U1 snRNP-specific protein C [Equus caballus]
SNRPC - small nuclear ribonucleoprotein polypeptide C
ENSCJAT00000029828 - null
tr|G1U072|G1U072... - pep:novel chromosome:oryCun2:12:24871878:24887729:1 gene:ENSOCUG00000026668 transcript:ENSOCUT000000...
gi|114607004, gi... - gi|114700426|ref|XP_515370.2| PREDICTED: similar to U1 snRNP-specific protein C [Pan troglodytes], g...
4.0E-26 [1..61] [1..61]
CE09232 - U1 small nuclear ribonucleoprotein C status:Confirmed UniProt:P90815 protein_id:AAB37732.1
1.0E-25 [1..61] [1..61]
RU1C_RAT - U1 small nuclear ribonucleoprotein C OS=Rattus norvegicus GN=Snrpc PE=3 SV=1
RU1C_MOUSE - U1 small nuclear ribonucleoprotein C OS=Mus musculus GN=Snrpc PE=1 SV=1
1.0E-25 [1..61] [1..61]
RU1C_ARATH - U1 small nuclear ribonucleoprotein C OS=Arabidopsis thaliana GN=At4g03120 PE=2 SV=1
5.0E-23 [1..60] [1..62]
RU1C_NEUCR - U1 small nuclear ribonucleoprotein C OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708....
gi|32412708, gi|... - gi|32412708|ref|XP_326834.1| hypothetical protein [Neurospora crassa], gi|28922972|gb|EAA32191.1| pr...
9.0E-21 [1..59] [1..63]
usp103 - U1 snRNP-associated protein Usp103
RU1C_SCHPO - U1 small nuclear ribonucleoprotein C OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=usp10...
2.0E-20 [1..57] [1..57]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRYYCEYCH SYLTHDTLSV RKSHLVGKNH LRITADYYRN KARDIINKHN HKRRHIGKRG  60
   61 RKERENSSQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.290 0.120 commitment complex a.35.1 lambda repressor-like DNA-binding domains
View Download 0.299 0.071 commitment complex a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.508 0.070 commitment complex a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.382 0.045 commitment complex a.64.1 Saposin
View Download 0.299 0.012 commitment complex a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.285 N/A N/A d.47.1 Ribosomal protein L11, N-terminal domain
View Download 0.277 N/A N/A a.4.1 Homeodomain-like
View Download 0.264 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.224 N/A N/A d.50.3 PI-Pfui intein middle domain
View Download 0.218 N/A N/A a.22.1 Histone-fold
View Download 0.212 N/A N/A a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.211 N/A N/A a.64.1 Saposin
View Download 0.210 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.209 N/A N/A a.64.1 Saposin

Predicted functions:

Term Confidence Notes
U1 snRNA binding 4.35911393951689 bayes_pls_golite062009
transcription regulator activity 3.60566283434269 bayes_pls_golite062009
DNA binding 3.55661236227495 bayes_pls_golite062009
nucleic acid binding 3.48507500696529 bayes_pls_golite062009
snRNA binding 3.38579636849163 bayes_pls_golite062009
RNA binding 3.1651307444578 bayes_pls_golite062009
transcription factor activity 2.66585743129629 bayes_pls_golite062009
binding 2.51459778938853 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.8286807075508 bayes_pls_golite062009
transcription activator activity 1.42518458564872 bayes_pls_golite062009
mRNA binding 1.30742677372942 bayes_pls_golite062009
chromatin binding 0.89589330553881 bayes_pls_golite062009
sequence-specific DNA binding 0.8936929860974 bayes_pls_golite062009
transcription repressor activity 0.882178479686399 bayes_pls_golite062009
transcription factor binding 0.67452735768188 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.47352407708364 bayes_pls_golite062009
protein binding 0.308413944574415 bayes_pls_golite062009
transcription cofactor activity 0.26487559807277 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
structure-specific DNA binding 0.240825841910931 bayes_pls_golite062009
double-stranded DNA binding 0.0129353639725593 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [70-231]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NETLKVTCLS NKEKRHIMHV KKMNQKELAQ TSIDTLKLLY DGSPGYSKVF VDANRFDIGD  60
   61 LVKASKLPQR ANEKSAHHSF KQTSRSRDET CESNPFPRLN NPKKLEPPKI LSQWSNTIPK 120
  121 TSIFYSVDIL QTTIKESKKR MHSDGIRKPS SANGYKRRRY GN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle