Bait Protein: | PGA1 |
Organism: | Saccharomyces cerevisiae |
Publication: | Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65 |
Comments: | No comments. |
Raw Data: |
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FILTERED Run Results:
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Hit Protein | Protein Desc | Sequence Count | Spectrum Count | Sequence Coverage | NSAF | Mol. Wt. | |
[ |
ENO1 | Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosph... | 17 | 42 | 48.1% | 0.203 | 46816 |
[ |
RPP2B | Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction ... | 3 | 3 | 36.4% | 0.0576 | 11050 |
[ |
TPI1 | Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availabi... | 4 | 4 | 35.1% | 0.0341 | 26795 |
[ |
FBA1 | Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversio... | 7 | 14 | 25.3% | 0.0824 | 39621 |
[ |
PGA1 | Essential component of GPI-mannosyltransferase II, responsible for second mannose addition to GPI pr... | 8 | 8 | 24.2% | 0.0853 | 22383 |
[ |
GPM1 | Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycer... | 5 | 7 | 20.6% | 0.0598 | 27609 |
[ |
ADH1 | Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the red... | 7 | 18 | 19.0% | 0.109 | 36849 |
[ |
HSP26 | Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that ... | 2 | 3 | 16.8% | 0.0296 | 23880 |
[ |
TRP1 | Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis; in 20... | 2 | 2 | 15.7% | 0.0189 | 24057 |
[ |
BMH1 | 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and D... | 2 | 2 | 15.0% | 0.0158 | 30091 |
[ |
BMH2 | 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and D... | 2 | 2 | 14.7% | 0.0155 | 31061 |
[ |
ASC1 | G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 th... | 2 | 2 | 10.7% | 0.0132 | 34805 |
[ |
CMK2 | Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan depend... | 3 | 3 | 10.5% | 0.0142 | 50448 |
[ |
ILV2 | Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is ... | 5 | 5 | 10.3% | 0.0154 | 74937 |
[ |
ADE5,7 | Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole... | 3 | 4 | 7.9% | 0.0105 | 86068 |
[ |
YDJ1 | Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein trans... | 3 | 3 | 7.8% | 0.0155 | 44671 |
[ |
RPP0 | Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphoryl... | 2 | 3 | 7.7% | 0.0203 | 33717 |
[ |
MET6 | Cobalamin-independent methionine synthase, involved in methionine biosynthesis and regeneration; req... | 3 | 3 | 7.3% | 0.00826 | 85860 |
[ |
EFT2, EFT1 | Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein s... | 5 | 5 | 6.8% | 0.0125 | 93289 |
[ |
EFT2, EFT1 | Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein s... | 5 | 5 | 6.8% | 0.0125 | 93289 |
[ |
RPG1 | eIF3a subunit of the core complex of translation initiation factor 3 (eIF3), essential for translati... | 3 | 3 | 6.8% | 0.00657 | 110344 |
[ |
GCD6 | Catalytic epsilon subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchang... | 2 | 2 | 6.6% | 0.00593 | 81161 |
[ |
KAR2 | ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding i... | 3 | 3 | 6.6% | 0.00929 | 74468 |
[ |
PHO84 | High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated... | 2 | 2 | 6.5% | 0.0072 | 64382 |
[ |
CYS4 | Cystathionine beta-synthase, catalyzes synthesis of cystathionine from serine and homocysteine, the ... | 2 | 2 | 6.5% | 0.00833 | 56022 |
[ |
GUT1 | Glycerol kinase, converts glycerol to glycerol-3-phosphate; glucose repression of expression is medi... | 2 | 2 | 6.2% | 0.00596 | 79824 |
[ |
POX1 | Fatty-acyl coenzyme A oxidase, involved in the fatty acid beta-oxidation pathway; localized to the p... | 2 | 3 | 6.1% | 0.00847 | 84042 |
[ |
HSC82 | Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, a... | 3 | 3 | 6.1% | 0.00899 | 80900 |
[ |
SSE1 | ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded protein... | 3 | 3 | 5.8% | 0.00914 | 77367 |
[ |
TUB2 | Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymeriz... | 2 | 2 | 5.5% | 0.00924 | 50923 |
[ |
GFA1 | Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of glucosamine-6-P and glut... | 2 | 2 | 4.9% | 0.00589 | 80047 |
[ |
PGI1 | Glycolytic enzyme phosphoglucose isomerase, catalyzes the interconversion of glucose-6-phosphate and... | 2 | 2 | 4.7% | 0.00762 | 61299 |
[ |
YHR020W | Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ... | 2 | 2 | 4.2% | 0.00614 | 77386 |
[ |
PFK1 | Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaer... | 2 | 2 | 4.0% | 0.00428 | 107970 |
[ |
TFP1 | Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase; protein prec... | 4 | 4 | 3.9% | 0.00789 | 118637 |
[ |
MET10 | Subunit alpha of assimilatory sulfite reductase, which converts sulfite into sulfide | 2 | 3 | 3.6% | 0.00612 | 114829 |
[ |
NST1 | Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the spli... | 2 | 2 | 2.4% | 0.00341 | 141514 |
[ |
YEF3 | Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes b... | 2 | 2 | 2.4% | 0.00405 | 115945 |