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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.712939028606]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
PAM18
  • mitochondrial inner membrane presequence translocase complex
  • mitochondrion
  • presequence translocase-associated import motor
    		•
  • protein import into mitochondrial matrix
    		•
  • protein transporter activity
  • unfolded protein binding
  • ATPase activator activity
    		•
    TIM44
  • mitochondrial matrix
  • mitochondrion
  • presequence translocase-associated import motor
    		•
  • protein import into mitochondrial matrix
    		•
  • protein transporter activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    presequence translocase-associated import motor 1.0611E-6 2 7 2 6292
    mitochondrial inner membrane presequence translocase complex 2.779E-6 2 11 2 6292
    mitochondrial membrane part 2.5011E-4 2 100 2 6292
    mitochondrial inner membrane 7.6048E-4 2 174 2 6292
    organelle inner membrane 8.5997E-4 2 185 2 6292
    mitochondrial membrane 1.7808E-3 2 266 2 6292
    mitochondrial envelope 2.4514E-3 2 312 2 6292
    mitochondrial part 5.6881E-3 2 475 2 6292
    envelope 6.43E-3 2 505 2 6292
    organelle envelope 6.43E-3 2 505 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein import into mitochondrial matrix 1.2783E-5 2 23 2 6292
    intracellular protein transmembrane transport 4.3504E-5 2 42 2 6292
    protein localization in mitochondrion 6.9626E-5 2 53 2 6292
    protein targeting to mitochondrion 6.9626E-5 2 53 2 6292
    mitochondrial transport 1.0838E-4 2 66 2 6292
    transmembrane transport 1.7194E-4 2 83 2 6292
    protein import 2.9194E-4 2 108 2 6292
    protein localization in organelle 5.5711E-4 2 149 2 6292
    mitochondrion organization 6.1087E-4 2 156 2 6292
    protein targeting 1.3892E-3 2 235 2 6292
    intracellular protein transport 1.6363E-3 2 255 2 6292
    protein transport 1.8213E-3 2 269 2 6292
    establishment of protein localization 1.8485E-3 2 271 2 6292
    cellular protein localization 1.8898E-3 2 274 2 6292
    cellular macromolecule localization 2.0305E-3 2 284 2 6292
    protein localization 2.3118E-3 2 303 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein transporter activity 8.3521E-5 2 58 2 6292
    ATPase activator activity 2.224E-3 2 7 1 6292
    substrate-specific transporter activity 2.8436E-3 2 336 2 6292
    ATPase regulator activity 3.4937E-3 2 11 1 6292
    transporter activity 4.1132E-3 2 404 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle