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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.916270856726]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
CSE4
  • condensed nuclear chromosome, centromeric region
  • extrachromosomal circular DNA
  • nuclear nucleosome
  • kinetochore
    		•
  • mitotic sister chromatid segregation
  • 2-micrometer plasmid partitioning
    		•
  • sequence-specific DNA binding
  • centromeric DNA binding
    		•
    MIF2
  • nucleus
  • condensed nuclear chromosome kinetochore
    		•
  • chromosome segregation
  • mitotic spindle organization in nucleus
    		•
  • centromeric DNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    condensed chromosome, centromeric region 7.5032E-5 2 55 2 6292
    condensed nuclear chromosome, centromeric region 7.5032E-5 2 55 2 6292
    kinetochore 8.9432E-5 2 60 2 6292
    chromosome, centromeric region 1.1171E-4 2 67 2 6292
    condensed nuclear chromosome 1.8468E-4 2 86 2 6292
    condensed chromosome 2.2085E-4 2 94 2 6292
    extrachromosomal circular DNA 6.3568E-4 2 2 1 6292
    extrachromosomal DNA 6.3568E-4 2 2 1 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292
    nuclear nucleosome 3.811E-3 2 12 1 6292
    nucleosome 3.811E-3 2 12 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    chromosome segregation 4.1068E-4 2 128 2 6292
    plasmid partitioning 1.2712E-3 2 4 1 6292
    2-micrometer plasmid partitioning 1.2712E-3 2 4 1 6292
    mitotic cell cycle 1.6363E-3 2 255 2 6292
    M phase 2.1762E-3 2 294 2 6292
    plasmid maintenance 3.4937E-3 2 11 1 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    cell cycle 6.95E-3 2 525 2 6292
    mitotic spindle organization in nucleus 8.248E-3 2 26 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    centromeric DNA binding 1.4147E-6 2 8 2 6292
    sequence-specific DNA binding 6.1895E-5 2 50 2 6292
    DNA binding 1.6492E-3 2 256 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle