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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.953117287589]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

CBF3 complex 3.0316E-7 2 4 2 6292
kinetochore 8.9432E-5 2 60 2 6292
chromosome, centromeric region 1.1171E-4 2 67 2 6292
RAVE complex 9.5344E-4 2 3 1 6292
chromosomal part 1.413E-3 2 237 2 6292
chromosome 1.8898E-3 2 274 2 6292
SCF ubiquitin ligase complex 3.4937E-3 2 11 1 6292
cullin-RING ubiquitin ligase complex 4.4455E-3 2 14 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

centromere complex assembly 1.5158E-7 2 3 2 6292
kinetochore assembly 1.5158E-7 2 3 2 6292
kinetochore organization 1.5158E-7 2 3 2 6292
protein-DNA complex assembly 3.744E-5 2 39 2 6292
cellular protein complex assembly 7.2304E-5 2 54 2 6292
organelle assembly 1.1854E-4 2 69 2 6292
protein complex biogenesis 6.0304E-4 2 155 2 6292
protein complex assembly 6.0304E-4 2 155 2 6292
cellular macromolecular complex assembly 8.3223E-4 2 182 2 6292
cellular macromolecular complex subunit organization 1.6882E-3 2 259 2 6292
macromolecular complex assembly 1.9877E-3 2 281 2 6292
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2.224E-3 2 7 1 6292
protein neddylation 2.224E-3 2 7 1 6292
macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
protein ubiquitination during ubiquitin-dependent protein catabolic process 3.4937E-3 2 11 1 6292
regulation of protein complex assembly 3.4937E-3 2 11 1 6292
cellular component assembly 3.7349E-3 2 385 2 6292
regulation of cellular component biogenesis 5.7138E-3 2 18 1 6292
pH reduction 7.6148E-3 2 24 1 6292
intracellular pH reduction 7.6148E-3 2 24 1 6292
vacuolar acidification 7.6148E-3 2 24 1 6292
chromosome organization 7.7677E-3 2 555 2 6292
regulation of exit from mitosis 7.9314E-3 2 25 1 6292
exit from mitosis 7.9314E-3 2 25 1 6292
regulation of intracellular pH 7.9314E-3 2 25 1 6292
regulation of cellular pH 7.9314E-3 2 25 1 6292
regulation of pH 9.1975E-3 2 29 1 6292
G2/M transition of mitotic cell cycle 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

sequence-specific DNA binding 6.1895E-5 2 50 2 6292
DNA binding 1.6492E-3 2 256 2 6292
centromeric DNA binding 2.5415E-3 2 8 1 6292
DNA bending activity 4.1283E-3 2 13 1 6292
DNA replication origin binding 4.1283E-3 2 13 1 6292

YRC Informatics Platform - Version 3.0
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