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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.40899554616]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
PRI1
  • alpha DNA polymerase:primase complex
    		•
  • DNA replication initiation
  • lagging strand elongation
  • DNA replication
  • DNA replication, synthesis of RNA primer
    		•
  • DNA primase activity
    		•
    PRI2
  • nuclear envelope
  • nucleus
  • alpha DNA polymerase:primase complex
    		•
  • DNA replication initiation
  • lagging strand elongation
  • DNA replication
  • DNA synthesis involved in DNA repair
  • DNA replication, synthesis of RNA primer
    		•
  • DNA primase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    alpha DNA polymerase:primase complex 1.0611E-6 2 7 2 6292
    nuclear replisome 7.7306E-6 2 18 2 6292
    replisome 7.7306E-6 2 18 2 6292
    nuclear replication fork 9.6001E-6 2 20 2 6292
    replication fork 4.3504E-5 2 42 2 6292
    protein-DNA complex 8.0641E-5 2 57 2 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA replication, synthesis of RNA primer 5.0527E-7 2 5 2 6292
    lagging strand elongation 7.7306E-6 2 18 2 6292
    DNA strand elongation 2.3495E-5 2 31 2 6292
    DNA strand elongation involved in DNA replication 2.3495E-5 2 31 2 6292
    DNA replication initiation 2.6678E-5 2 33 2 6292
    DNA-dependent DNA replication 1.678E-4 2 82 2 6292
    DNA replication 3.791E-4 2 123 2 6292
    DNA synthesis involved in DNA repair 1.2712E-3 2 4 1 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA primase activity 5.0527E-8 2 2 2 6292
    RNA polymerase activity 2.8346E-5 2 34 2 6292
    DNA-directed RNA polymerase activity 2.8346E-5 2 34 2 6292
    nucleotidyltransferase activity 7.0879E-4 2 168 2 6292
    transferase activity, transferring phosphorus-containing groups 4.4459E-3 2 420 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle