From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.773879043] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
COX1 |
|
|
|
COX13 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mitochondrial respiratory chain complex IV | 3.3348E-6 | 2 | 12 | 2 | 6292 |
respiratory chain complex IV | 3.3348E-6 | 2 | 12 | 2 | 6292 |
mitochondrial respiratory chain | 1.6421E-5 | 2 | 26 | 2 | 6292 |
respiratory chain | 1.6421E-5 | 2 | 26 | 2 | 6292 |
mitochondrial membrane part | 2.5011E-4 | 2 | 100 | 2 | 6292 |
mitochondrial inner membrane | 7.6048E-4 | 2 | 174 | 2 | 6292 |
organelle inner membrane | 8.5997E-4 | 2 | 185 | 2 | 6292 |
mitochondrial membrane | 1.7808E-3 | 2 | 266 | 2 | 6292 |
mitochondrial envelope | 2.4514E-3 | 2 | 312 | 2 | 6292 |
mitochondrial part | 5.6881E-3 | 2 | 475 | 2 | 6292 |
envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
organelle envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
aerobic respiration | 1.7194E-4 | 2 | 83 | 2 | 6292 |
cellular respiration | 2.3525E-4 | 2 | 97 | 2 | 6292 |
energy derivation by oxidation of organic compounds | 5.5711E-4 | 2 | 149 | 2 | 6292 |
generation of precursor metabolites and energy | 9.5571E-4 | 2 | 195 | 2 | 6292 |
mitochondrial electron transport, cytochrome c to oxygen | 3.1764E-3 | 2 | 10 | 1 | 6292 |
respiratory electron transport chain | 7.9314E-3 | 2 | 25 | 1 | 6292 |
electron transport chain | 7.9314E-3 | 2 | 25 | 1 | 6292 |
ATP synthesis coupled electron transport | 7.9314E-3 | 2 | 25 | 1 | 6292 |
mitochondrial ATP synthesis coupled electron transport | 7.9314E-3 | 2 | 25 | 1 | 6292 |
oxidation reduction | 8.248E-3 | 2 | 26 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
heme-copper terminal oxidase activity | 3.3348E-6 | 2 | 12 | 2 | 6292 |
cytochrome-c oxidase activity | 3.3348E-6 | 2 | 12 | 2 | 6292 |
oxidoreductase activity, acting on heme group of donors | 3.3348E-6 | 2 | 12 | 2 | 6292 |
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor | 3.3348E-6 | 2 | 12 | 2 | 6292 |
hydrogen ion transmembrane transporter activity | 7.2304E-5 | 2 | 54 | 2 | 6292 |
monovalent inorganic cation transmembrane transporter activity | 8.6451E-5 | 2 | 59 | 2 | 6292 |
inorganic cation transmembrane transporter activity | 2.5516E-4 | 2 | 101 | 2 | 6292 |
cation transmembrane transporter activity | 3.4879E-4 | 2 | 118 | 2 | 6292 |
ion transmembrane transporter activity | 5.3483E-4 | 2 | 146 | 2 | 6292 |
substrate-specific transmembrane transporter activity | 1.7943E-3 | 2 | 267 | 2 | 6292 |
oxidoreductase activity | 1.9877E-3 | 2 | 281 | 2 | 6292 |
transmembrane transporter activity | 2.3578E-3 | 2 | 306 | 2 | 6292 |
substrate-specific transporter activity | 2.8436E-3 | 2 | 336 | 2 | 6292 |
transporter activity | 4.1132E-3 | 2 | 404 | 2 | 6292 |