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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 2.07241592154]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
CIK1
  • spindle pole body
  • spindle
  • kinesin complex
  • cytoplasmic microtubule
    		•
  • establishment of mitotic spindle orientation
  • mitotic sister chromatid segregation
  • mitotic spindle organization in nucleus
  • karyogamy involved in conjugation with cellular fusion
  • meiosis
    		•
  • microtubule motor activity
    		•
    KAR3
  • spindle pole body
  • microtubule
    		•
  • mitotic sister chromatid cohesion
  • mitosis
  • karyogamy involved in conjugation with cellular fusion
  • meiosis
    		•
  • microtubule motor activity
  • motor activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    microtubule 2.3495E-5 2 31 2 6292
    microtubule organizing center 9.8679E-5 2 63 2 6292
    spindle pole body 9.8679E-5 2 63 2 6292
    spindle pole 1.151E-4 2 68 2 6292
    spindle 1.9786E-4 2 89 2 6292
    microtubule cytoskeleton 2.8118E-4 2 106 2 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292
    kinesin complex 2.224E-3 2 7 1 6292
    cytoplasmic microtubule 4.4455E-3 2 14 1 6292
    microtubule associated complex 5.7138E-3 2 18 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    karyogamy involved in conjugation with cellular fusion 7.7306E-6 2 18 2 6292
    karyogamy 7.7306E-6 2 18 2 6292
    organelle fusion 7.2304E-5 2 54 2 6292
    nucleus organization 7.7811E-5 2 56 2 6292
    mitotic sister chromatid segregation 1.0838E-4 2 66 2 6292
    sister chromatid segregation 1.1854E-4 2 69 2 6292
    mitosis 2.7062E-4 2 104 2 6292
    nuclear division 2.8118E-4 2 106 2 6292
    organelle fission 3.1973E-4 2 113 2 6292
    conjugation with cellular fusion 3.9158E-4 2 125 2 6292
    conjugation 3.979E-4 2 126 2 6292
    chromosome segregation 4.1068E-4 2 128 2 6292
    M phase of mitotic cell cycle 4.1068E-4 2 128 2 6292
    multi-organism process 5.13E-4 2 143 2 6292
    M phase of meiotic cell cycle 6.427E-4 2 160 2 6292
    meiosis 6.427E-4 2 160 2 6292
    meiotic cell cycle 6.7534E-4 2 164 2 6292
    reproductive cellular process 1.1194E-3 2 211 2 6292
    reproductive process 1.1301E-3 2 212 2 6292
    sexual reproduction 1.3656E-3 2 233 2 6292
    mitotic cell cycle 1.6363E-3 2 255 2 6292
    M phase 2.1762E-3 2 294 2 6292
    reproduction 2.7096E-3 2 328 2 6292
    establishment of spindle localization 3.1764E-3 2 10 1 6292
    establishment of spindle orientation 3.1764E-3 2 10 1 6292
    establishment of mitotic spindle localization 3.1764E-3 2 10 1 6292
    spindle localization 3.1764E-3 2 10 1 6292
    establishment of mitotic spindle orientation 3.1764E-3 2 10 1 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    cell cycle 6.95E-3 2 525 2 6292
    mitotic sister chromatid cohesion 7.2981E-3 2 23 1 6292
    chromosome organization 7.7677E-3 2 555 2 6292
    mitotic spindle organization in nucleus 8.248E-3 2 26 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    microtubule motor activity 2.2737E-6 2 10 2 6292
    motor activity 7.7306E-6 2 18 2 6292
    nucleoside-triphosphatase activity 2.7262E-3 2 329 2 6292
    hydrolase activity, acting on acid anhydrides 3.1391E-3 2 353 2 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.1391E-3 2 353 2 6292
    pyrophosphatase activity 3.1391E-3 2 353 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle