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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rpp0. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AHP1
  • cytoplasm
  • response to oxidative stress
  • response to metal ion
  • thioredoxin peroxidase activity
  • HHF1, HHF2
  • nucleus
  • nucleoplasm part
  • nuclear nucleosome
  • chromosome
  • replication fork protection complex
  • chromatin remodeling complex
  • nucleosome
  • histone acetyltransferase complex
  • nucleoplasm
  • histone H3-K79 methylation
  • DNA repair
  • negative regulation of transcription
  • chromatin assembly or disassembly
  • positive regulation of transcription
  • nucleosome assembly
  • DNA binding
  • HXT7
  • mitochondrion
  • plasma membrane
  • hexose transport
  • fructose transmembrane transporter activity
  • glucose transmembrane transporter activity
  • mannose transmembrane transporter activity
  • HYP2
  • cytoplasm
  • mitochondrion
  • ribosome
  • translational initiation
  • translation initiation factor activity
  • protein binding
  • MNP1
  • mitochondrion
  • mitochondrial ribosome
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • NMD3
  • cytosol
  • ribosomal large subunit export from nucleus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • RNA binding
  • protein binding
  • RGI1
  • nucleus
  • cytoplasm
  • biological_process
  • molecular_function
  • RPP0
  • ribosomal large subunit assembly
  • translational elongation
  • translation
  • structural constituent of ribosome
  • RTC3
  • nucleus
  • cytoplasm
  • RNA metabolic process
  • molecular_function
  • TIF6
  • nucleus
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • ribosomal subunit export from nucleus
  • ribosomal large subunit biogenesis
  • processing of 27S pre-rRNA
  • ribosomal large subunit binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    replication fork protection complex 3.1764E-3 10 2 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosomal large subunit biogenesis 1.1993E-4 10 65 3 6292
    establishment of ribosome localization 7.2406E-4 10 26 2 6292
    ribosome localization 7.2406E-4 10 26 2 6292
    ribosomal subunit export from nucleus 7.2406E-4 10 26 2 6292
    histone H3-K79 methylation 1.5893E-3 10 1 1 6292
    ribosomal large subunit assembly 1.8038E-3 10 41 2 6292
    cellular macromolecular complex assembly 2.4587E-3 10 182 3 6292
    histone lysine methylation 3.1764E-3 10 2 1 6292
    ribosomal subunit assembly 3.228E-3 10 55 2 6292
    establishment of organelle localization 3.228E-3 10 55 2 6292
    ribosome assembly 4.3489E-3 10 64 2 6292
    organelle assembly 5.0393E-3 10 69 2 6292
    cellular macromolecular complex subunit organization 6.671E-3 10 259 3 6292
    organelle localization 7.565E-3 10 85 2 6292
    macromolecular complex assembly 8.3691E-3 10 281 3 6292
    ribonucleoprotein complex assembly 8.8178E-3 10 92 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosomal large subunit binding 1.5893E-3 10 1 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle