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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Mms2. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ubiquitin conjugating enzyme complex 3.0316E-7 4 2 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

postreplication repair 4.6226E-5 4 18 2 6292
protein polyubiquitination 6.3408E-5 4 21 2 6292
protein ubiquitination 6.2218E-4 4 65 2 6292
protein modification by small protein conjugation 1.0884E-3 4 86 2 6292
positive regulation of Ras GTPase activity 1.2712E-3 4 2 1 6292
negative regulation of cAMP biosynthetic process 1.2712E-3 4 2 1 6292
regulation of Ras GTPase activity 1.2712E-3 4 2 1 6292
negative regulation of cAMP metabolic process 1.2712E-3 4 2 1 6292
negative regulation of nucleotide biosynthetic process 1.2712E-3 4 2 1 6292
negative regulation of cyclic nucleotide metabolic process 1.2712E-3 4 2 1 6292
negative regulation of cyclic nucleotide biosynthetic process 1.2712E-3 4 2 1 6292
positive regulation of GTPase activity 1.2712E-3 4 2 1 6292
negative regulation of nucleotide metabolic process 1.2712E-3 4 2 1 6292
response to stress 1.8449E-3 4 497 3 6292
positive regulation of hydrolase activity 1.9063E-3 4 3 1 6292
protein modification by small protein conjugation or removal 1.9066E-3 4 114 2 6292
cAMP biosynthetic process 2.5411E-3 4 4 1 6292
regulation of cAMP metabolic process 2.5411E-3 4 4 1 6292
regulation of cAMP biosynthetic process 2.5411E-3 4 4 1 6292
regulation of nucleotide biosynthetic process 2.5411E-3 4 4 1 6292
regulation of cyclic nucleotide biosynthetic process 2.5411E-3 4 4 1 6292
cyclic nucleotide biosynthetic process 2.5411E-3 4 4 1 6292
cyclic nucleotide metabolic process 2.5411E-3 4 4 1 6292
regulation of cyclic nucleotide metabolic process 2.5411E-3 4 4 1 6292
cAMP metabolic process 2.5411E-3 4 4 1 6292
purine ribonucleotide catabolic process 3.1756E-3 4 5 1 6292
ribonucleoside triphosphate catabolic process 3.1756E-3 4 5 1 6292
purine ribonucleoside triphosphate catabolic process 3.1756E-3 4 5 1 6292
regulation of nucleotide catabolic process 3.1756E-3 4 5 1 6292
regulation of GTPase activity 3.1756E-3 4 5 1 6292
regulation of GTP catabolic process 3.1756E-3 4 5 1 6292
regulation of purine nucleotide catabolic process 3.1756E-3 4 5 1 6292
ribonucleotide catabolic process 3.1756E-3 4 5 1 6292
purine nucleoside triphosphate catabolic process 3.1756E-3 4 5 1 6292
GTP catabolic process 3.1756E-3 4 5 1 6292
purine nucleotide catabolic process 3.1756E-3 4 5 1 6292
regulation of Ras protein signal transduction 3.8098E-3 4 6 1 6292
negative regulation of Ras protein signal transduction 3.8098E-3 4 6 1 6292
negative regulation of cell communication 3.8098E-3 4 6 1 6292
negative regulation of small GTPase mediated signal transduction 3.8098E-3 4 6 1 6292
regulation of small GTPase mediated signal transduction 3.8098E-3 4 6 1 6292
negative regulation of signaling pathway 3.8098E-3 4 6 1 6292
regulation of nucleotide metabolic process 4.4437E-3 4 7 1 6292
nucleoside triphosphate catabolic process 4.4437E-3 4 7 1 6292
GTP metabolic process 4.4437E-3 4 7 1 6292
nucleotide catabolic process 5.0773E-3 4 8 1 6292
DNA repair 5.3374E-3 4 192 2 6292
regulation of hydrolase activity 5.7106E-3 4 9 1 6292
response to stimulus 6.5381E-3 4 766 3 6292
response to DNA damage stimulus 7.9954E-3 4 236 2 6292
regulation of cell communication 8.8726E-3 4 14 1 6292
nucleobase, nucleoside, nucleotide and nucleic acid catabolic process 9.5041E-3 4 15 1 6292
nucleobase, nucleoside and nucleotide catabolic process 9.5041E-3 4 15 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ubiquitin-protein ligase activity 4.7822E-4 4 57 2 6292
small conjugating protein ligase activity 5.6601E-4 4 62 2 6292
acid-amino acid ligase activity 7.4238E-4 4 71 2 6292
ligase activity, forming carbon-nitrogen bonds 1.2994E-3 4 94 2 6292
ligase activity 3.2825E-3 4 150 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle