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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 4 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
KAP95
  • cytoplasm
  • nuclear pore
    		•
  • protein import into nucleus
  • nuclear pore complex assembly
    		•
  • protein transmembrane transporter activity
    		•
    NUP2
  • nuclear chromatin
  • mitochondrion
  • nuclear pore
    		•
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • chromatin silencing
  • protein export from nucleus
  • chromatin silencing at telomere
  • ribosomal protein import into nucleus
    		•
  • structural molecule activity
    		•
    NUP60
  • nuclear pore
    		•
  • nucleocytoplasmic transport
  • telomere maintenance
  • protein import into nucleus, docking
    		•
  • structural constituent of nuclear pore
    		•
    SRP1
  • nucleus
  • cytoplasm
    		•
  • nucleocytoplasmic transport
    		•
  • protein transmembrane transporter activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    pore complex 2.1179E-6 4 52 3 6292
    nuclear pore 2.1179E-6 4 52 3 6292
    nuclear envelope 1.2179E-4 4 199 3 6292
    integral to membrane 2.5535E-4 4 255 3 6292
    intrinsic to membrane 2.7682E-4 4 262 3 6292
    endomembrane system 9.5789E-4 4 398 3 6292
    envelope 1.9337E-3 4 505 3 6292
    organelle envelope 1.9337E-3 4 505 3 6292
    membrane part 4.2752E-3 4 662 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear transport 1.741E-7 4 130 4 6292
    nucleocytoplasmic transport 1.741E-7 4 130 4 6292
    protein localization in nucleus 1.6583E-6 4 48 3 6292
    protein import into nucleus 1.6583E-6 4 48 3 6292
    nuclear import 1.6583E-6 4 48 3 6292
    protein import 1.9433E-5 4 108 3 6292
    protein localization in organelle 5.1173E-5 4 149 3 6292
    intracellular transport 5.908E-5 4 553 4 6292
    establishment of localization in cell 8.1397E-5 4 599 4 6292
    cellular localization 1.0815E-4 4 643 4 6292
    nuclear pore organization 1.1396E-4 4 28 2 6292
    protein targeting 2.0015E-4 4 235 3 6292
    intracellular protein transport 2.5535E-4 4 255 3 6292
    cellular macromolecular complex subunit organization 2.6748E-4 4 259 3 6292
    protein transport 2.9943E-4 4 269 3 6292
    establishment of protein localization 3.0611E-4 4 271 3 6292
    cellular protein localization 3.1631E-4 4 274 3 6292
    cellular macromolecule localization 3.5193E-4 4 284 3 6292
    protein localization 4.2667E-4 4 303 3 6292
    cellular protein complex assembly 4.2906E-4 4 54 2 6292
    nucleus organization 4.6154E-4 4 56 2 6292
    transport 6.2722E-4 4 997 4 6292
    pore complex assembly 6.3573E-4 4 1 1 6292
    nuclear pore complex assembly 6.3573E-4 4 1 1 6292
    establishment of localization 6.5541E-4 4 1008 4 6292
    macromolecular complex subunit organization 6.9425E-4 4 357 3 6292
    localization 8.0172E-4 4 1060 4 6292
    macromolecule localization 9.5079E-4 4 397 3 6292
    protein import into nucleus, docking 2.5411E-3 4 4 1 6292
    protein complex biogenesis 3.5019E-3 4 155 2 6292
    protein complex assembly 3.5019E-3 4 155 2 6292
    cellular macromolecular complex assembly 4.8049E-3 4 182 2 6292
    cellular component biogenesis 4.9063E-3 4 694 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein transmembrane transporter activity 1.0898E-5 4 9 2 6292
    macromolecule transmembrane transporter activity 1.0898E-5 4 9 2 6292
    protein transporter activity 4.952E-4 4 58 2 6292
    structural constituent of nuclear pore 2.5411E-3 4 4 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle