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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AIR1
  • nucleus
  • nucleolus
  • TRAMP complex
  • mRNA export from nucleus
  • rRNA catabolic process
  • snRNA catabolic process
  • snoRNA catabolic process
  • tRNA catabolic process
  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
  • polynucleotide adenylyltransferase activity
  • AIR2
  • nucleus
  • TRAMP complex
  • mRNA export from nucleus
  • rRNA catabolic process
  • snRNA catabolic process
  • snoRNA catabolic process
  • tRNA catabolic process
  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
  • polynucleotide adenylyltransferase activity
  • MTR4
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • TRAMP complex
  • mRNA export from nucleus
  • rRNA catabolic process
  • ribosome biogenesis
  • tRNA catabolic process
  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
  • polyadenylation-dependent ncRNA catabolic process
  • ATP-dependent RNA helicase activity
  • PAP2
  • nucleus
  • TRAMP complex
  • mitotic chromosome condensation
  • ncRNA polyadenylation
  • mitotic sister chromatid cohesion
  • rRNA catabolic process
  • snRNA catabolic process
  • snoRNA catabolic process
  • tRNA catabolic process
  • DNA topological change
  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
  • polyadenylation-dependent ncRNA catabolic process
  • DNA-directed DNA polymerase activity
  • polynucleotide adenylyltransferase activity
  • PSO2
  • nucleus
  • DNA repair
  • double-strand break repair
  • 5'-3' exonuclease activity
  • damaged DNA binding
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • STE4
  • heterotrimeric G-protein complex
  • mating projection
  • plasma membrane
  • heterotrimeric G-protein complex cycle
  • invasive growth in response to glucose limitation
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
  • signal transducer activity
  • TRF5
  • nucleus
  • nucleolus
  • ncRNA polyadenylation
  • mitotic sister chromatid cohesion
  • rRNA catabolic process
  • snRNA catabolic process
  • snoRNA catabolic process
  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
  • DNA-directed DNA polymerase activity
  • polynucleotide adenylyltransferase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    TRAMP complex 1.0729E-12 8 4 4 6292
    nucleolus 1.8378E-3 8 211 3 6292
    heterotrimeric G-protein complex 3.8101E-3 8 3 1 6292
    macromolecular complex 5.1894E-3 8 1635 6 6292
    nuclear part 5.7545E-3 8 1103 5 6292
    protein complex 6.5954E-3 8 1137 5 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ncRNA polyadenylation 4.0935E-15 8 6 5 6292
    ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process 4.0935E-15 8 6 5 6292
    rRNA catabolic process 4.0935E-15 8 6 5 6292
    ncRNA catabolic process 4.0935E-15 8 6 5 6292
    polyadenylation-dependent RNA catabolic process 3.8176E-14 8 8 5 6292
    polyadenylation-dependent ncRNA catabolic process 3.8176E-14 8 8 5 6292
    ncRNA 3'-end processing 5.3905E-13 8 12 5 6292
    tRNA catabolic process 1.0729E-12 8 4 4 6292
    snRNA catabolic process 5.3619E-12 8 5 4 6292
    snoRNA catabolic process 5.3619E-12 8 5 4 6292
    RNA polyadenylation 4.4522E-11 8 26 5 6292
    snRNA metabolic process 1.3484E-10 8 9 4 6292
    RNA 3'-end processing 5.721E-10 8 42 5 6292
    snoRNA metabolic process 3.2598E-9 8 18 4 6292
    RNA catabolic process 1.5923E-8 8 80 5 6292
    rRNA metabolic process 2.4182E-7 8 137 5 6292
    modification-dependent macromolecule catabolic process 5.9524E-7 8 164 5 6292
    cellular catabolic process 1.9869E-6 8 415 6 6292
    ncRNA processing 2.291E-6 8 215 5 6292
    ncRNA metabolic process 5.5383E-6 8 257 5 6292
    catabolic process 5.6904E-6 8 496 6 6292
    cellular macromolecule catabolic process 6.4421E-6 8 265 5 6292
    tRNA metabolic process 8.3051E-6 8 120 4 6292
    macromolecule catabolic process 1.074E-5 8 294 5 6292
    RNA processing 3.7674E-5 8 380 5 6292
    mRNA transport 6.5054E-5 8 68 3 6292
    mRNA export from nucleus 6.5054E-5 8 68 3 6292
    RNA export from nucleus 1.0588E-4 8 80 3 6292
    RNA transport 1.0989E-4 8 81 3 6292
    nucleic acid transport 1.0989E-4 8 81 3 6292
    establishment of RNA localization 1.0989E-4 8 81 3 6292
    RNA localization 1.6068E-4 8 92 3 6292
    nucleobase, nucleoside, nucleotide and nucleic acid transport 1.8237E-4 8 96 3 6292
    nuclear export 2.2479E-4 8 103 3 6292
    mitotic sister chromatid cohesion 3.5318E-4 8 23 2 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.6683E-4 8 1566 7 6292
    nuclear transport 4.474E-4 8 130 3 6292
    nucleocytoplasmic transport 4.474E-4 8 130 3 6292
    sister chromatid cohesion 6.8844E-4 8 32 2 6292
    cellular nitrogen compound metabolic process 8.3438E-4 8 1770 7 6292
    nitrogen compound metabolic process 9.0281E-4 8 1791 7 6292
    gene expression 1.3613E-3 8 1283 6 6292
    primary metabolic process 2.0036E-3 8 2896 8 6292
    nucleic acid metabolic process 2.3473E-3 8 1415 6 6292
    cellular metabolic process 2.9013E-3 8 3033 8 6292
    mitotic sister chromatid segregation 2.9134E-3 8 66 2 6292
    RNA metabolic process 2.9766E-3 8 954 5 6292
    sister chromatid segregation 3.1803E-3 8 69 2 6292
    heterotrimeric G-protein complex cycle 3.8101E-3 8 3 1 6292
    metabolic process 3.9991E-3 8 3157 8 6292
    cellular macromolecule metabolic process 4.5244E-3 8 2285 7 6292
    macromolecule metabolic process 5.4192E-3 8 2349 7 6292
    purine ribonucleotide catabolic process 6.3431E-3 8 5 1 6292
    ribonucleoside triphosphate catabolic process 6.3431E-3 8 5 1 6292
    purine ribonucleoside triphosphate catabolic process 6.3431E-3 8 5 1 6292
    regulation of nucleotide catabolic process 6.3431E-3 8 5 1 6292
    regulation of GTPase activity 6.3431E-3 8 5 1 6292
    regulation of GTP catabolic process 6.3431E-3 8 5 1 6292
    regulation of purine nucleotide catabolic process 6.3431E-3 8 5 1 6292
    ribonucleotide catabolic process 6.3431E-3 8 5 1 6292
    purine nucleoside triphosphate catabolic process 6.3431E-3 8 5 1 6292
    GTP catabolic process 6.3431E-3 8 5 1 6292
    purine nucleotide catabolic process 6.3431E-3 8 5 1 6292
    mitosis 7.1004E-3 8 104 2 6292
    nuclear division 7.3681E-3 8 106 2 6292
    organelle fission 8.3409E-3 8 113 2 6292
    regulation of nucleotide metabolic process 8.8705E-3 8 7 1 6292
    nucleoside triphosphate catabolic process 8.8705E-3 8 7 1 6292
    GTP metabolic process 8.8705E-3 8 7 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    polynucleotide adenylyltransferase activity 1.6077E-11 8 6 4 6292
    adenylyltransferase activity 7.6363E-10 8 13 4 6292
    nucleotidyltransferase activity 3.1578E-5 8 168 4 6292
    transferase activity, transferring phosphorus-containing groups 1.1041E-3 8 420 4 6292
    5'-3' exonuclease activity 7.6075E-3 8 6 1 6292
    DNA-directed DNA polymerase activity 7.9172E-3 8 110 2 6292
    DNA polymerase activity 8.6291E-3 8 115 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle