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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 510.10
Complex Size: 14 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RPA12
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA135
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA14
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • regulation of cell size
  • telomere maintenance
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA190
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA34
  • nucleus
  • DNA-directed RNA polymerase I complex
  • nucleolus
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA43
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA49
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • regulation of cell size
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB10
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB5
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB8
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC10
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC19
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC40
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO26
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA-directed RNA polymerase I complex 5.803E-43 14 14 14 6292
    RNA polymerase complex 1.5389E-34 14 31 14 6292
    nuclear DNA-directed RNA polymerase complex 1.5389E-34 14 31 14 6292
    DNA-directed RNA polymerase complex 1.5389E-34 14 31 14 6292
    nucleolar part 9.6835E-32 14 45 14 6292
    nucleolus 1.4851E-21 14 211 14 6292
    nuclear lumen 8.3271E-17 14 453 14 6292
    DNA-directed RNA polymerase III complex 8.5614E-16 14 17 7 6292
    organelle lumen 1.7241E-14 14 660 14 6292
    intracellular organelle lumen 1.7241E-14 14 660 14 6292
    membrane-enclosed lumen 3.9609E-14 14 700 14 6292
    non-membrane-bounded organelle 3.3674E-12 14 959 14 6292
    intracellular non-membrane-bounded organelle 3.3674E-12 14 959 14 6292
    DNA-directed RNA polymerase II, core complex 1.9164E-11 14 12 5 6292
    nuclear part 2.4173E-11 14 1103 14 6292
    protein complex 3.7067E-11 14 1137 14 6292
    macromolecular complex 6.1412E-9 14 1635 14 6292
    DNA-directed RNA polymerase II, holoenzyme 8.7686E-8 14 56 5 6292
    nucleus 1.3856E-7 14 2041 14 6292
    nucleoplasm part 3.3867E-7 14 245 7 6292
    nucleoplasm 5.6397E-7 14 264 7 6292
    organelle part 6.6422E-7 14 2282 14 6292
    intracellular organelle part 6.6422E-7 14 2282 14 6292
    membrane-bounded organelle 7.6409E-4 14 3771 14 6292
    intracellular membrane-bounded organelle 7.6409E-4 14 3771 14 6292
    intracellular organelle 2.2276E-3 14 4070 14 6292
    organelle 2.2353E-3 14 4071 14 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription from RNA polymerase I promoter 8.4389E-35 14 30 14 6292
    transcription, DNA-dependent 3.6806E-16 14 503 14 6292
    RNA biosynthetic process 4.2349E-16 14 508 14 6292
    transcription 1.3747E-15 14 552 14 6292
    transcription from RNA polymerase III promoter 5.4428E-13 14 38 7 6292
    RNA metabolic process 3.1282E-12 14 954 14 6292
    cellular macromolecule biosynthetic process 6.7941E-11 14 1187 14 6292
    macromolecule biosynthetic process 6.957E-11 14 1189 14 6292
    gene expression 2.03E-10 14 1283 14 6292
    nucleic acid metabolic process 8.0503E-10 14 1415 14 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.3498E-9 14 1566 14 6292
    cellular biosynthetic process 3.38E-9 14 1567 14 6292
    biosynthetic process 4.6108E-9 14 1602 14 6292
    cellular nitrogen compound metabolic process 1.8728E-8 14 1770 14 6292
    nitrogen compound metabolic process 2.2103E-8 14 1791 14 6292
    cellular macromolecule metabolic process 6.7658E-7 14 2285 14 6292
    macromolecule metabolic process 9.9712E-7 14 2349 14 6292
    ribosome biogenesis 3.514E-6 14 346 7 6292
    ribonucleoprotein complex biogenesis 5.9152E-6 14 374 7 6292
    primary metabolic process 1.8826E-5 14 2896 14 6292
    cellular metabolic process 3.6009E-5 14 3033 14 6292
    metabolic process 6.3176E-5 14 3157 14 6292
    cellular component biogenesis 3.294E-4 14 694 7 6292
    transcription from RNA polymerase II promoter 5.5777E-4 14 335 5 6292
    cellular process 7.2188E-3 14 4426 14 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase activity 8.0776E-34 14 34 14 6292
    DNA-directed RNA polymerase activity 8.0776E-34 14 34 14 6292
    nucleotidyltransferase activity 5.4421E-23 14 168 14 6292
    transferase activity, transferring phosphorus-containing groups 2.8419E-17 14 420 14 6292
    transferase activity 2.4762E-13 14 797 14 6292
    catalytic activity 2.8771E-7 14 2150 14 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle