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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
MLH1
  • nucleus
  • mitochondrion
    		•
  • reciprocal meiotic recombination
  • meiotic mismatch repair
    		•
  • ATPase activity
  • DNA binding
  • ATP binding
    		•
    PMS1
  • nuclear chromosome
    		•
  • meiotic mismatch repair
  • mismatch repair
  • meiosis
    		•
  • ATPase activity
  • DNA binding
  • ATP binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    meiotic mismatch repair 1.819E-6 2 9 2 6292
    mismatch repair 1.7735E-5 2 27 2 6292
    meiosis I 1.5567E-4 2 79 2 6292
    M phase of meiotic cell cycle 6.427E-4 2 160 2 6292
    meiosis 6.427E-4 2 160 2 6292
    meiotic cell cycle 6.7534E-4 2 164 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    M phase 2.1762E-3 2 294 2 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    cell cycle 6.95E-3 2 525 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ATP binding 1.3945E-5 2 24 2 6292
    adenyl ribonucleotide binding 1.5158E-5 2 25 2 6292
    adenyl nucleotide binding 2.1979E-5 2 30 2 6292
    purine nucleoside binding 2.3495E-5 2 31 2 6292
    nucleoside binding 2.5061E-5 2 32 2 6292
    ribonucleotide binding 4.1432E-5 2 41 2 6292
    purine ribonucleotide binding 4.1432E-5 2 41 2 6292
    purine nucleotide binding 6.6999E-5 2 52 2 6292
    nucleotide binding 8.6451E-5 2 59 2 6292
    ATPase activity 1.1194E-3 2 211 2 6292
    DNA binding 1.6492E-3 2 256 2 6292
    nucleoside-triphosphatase activity 2.7262E-3 2 329 2 6292
    hydrolase activity, acting on acid anhydrides 3.1391E-3 2 353 2 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.1391E-3 2 353 2 6292
    pyrophosphatase activity 3.1391E-3 2 353 2 6292
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    Created and Maintained by: Michael Riffle