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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
MSH2
  • nucleus
  • nuclear chromosome
    		•
  • removal of nonhomologous ends
  • DNA recombination
  • meiotic gene conversion
  • meiotic mismatch repair
  • mismatch repair
  • chromatin silencing at silent mating-type cassette
  • mitotic recombination
    		•
  • ATPase activity
  • ATP binding
  • double-strand/single-strand DNA junction binding
  • DNA insertion or deletion binding
  • loop DNA binding
  • Y-form DNA binding
  • four-way junction DNA binding
  • guanine/thymine mispair binding
  • single base insertion or deletion binding
    		•
    MSH3
  • nucleus
  • cytoplasm
    		•
  • removal of nonhomologous ends
  • DNA recombination
  • meiotic mismatch repair
  • mismatch repair
  • mitotic recombination
    		•
  • double-strand/single-strand DNA junction binding
  • DNA insertion or deletion binding
  • loop DNA binding
  • Y-form DNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    removal of nonhomologous ends 5.0527E-7 2 5 2 6292
    DNA catabolic process, endonucleolytic 7.579E-7 2 6 2 6292
    meiotic mismatch repair 1.819E-6 2 9 2 6292
    gene conversion at mating-type locus 2.779E-6 2 11 2 6292
    DNA catabolic process 5.3053E-6 2 15 2 6292
    mating type switching 6.0632E-6 2 16 2 6292
    mating type determination 9.6001E-6 2 20 2 6292
    sex determination 9.6001E-6 2 20 2 6292
    cell fate commitment 1.2783E-5 2 23 2 6292
    mismatch repair 1.7735E-5 2 27 2 6292
    mitotic recombination 2.6678E-5 2 33 2 6292
    meiosis I 1.5567E-4 2 79 2 6292
    meiotic gene conversion 3.1786E-4 2 1 1 6292
    DNA recombination 3.2544E-4 2 114 2 6292
    reproductive process in single-celled organism 4.5024E-4 2 134 2 6292
    cell differentiation 5.4963E-4 2 148 2 6292
    reproductive developmental process 5.7222E-4 2 151 2 6292
    meiosis 6.427E-4 2 160 2 6292
    M phase of meiotic cell cycle 6.427E-4 2 160 2 6292
    meiotic cell cycle 6.7534E-4 2 164 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    reproductive cellular process 1.1194E-3 2 211 2 6292
    reproductive process 1.1301E-3 2 212 2 6292
    reproduction of a single-celled organism 1.1841E-3 2 217 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
    cellular developmental process 1.9175E-3 2 276 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    M phase 2.1762E-3 2 294 2 6292
    macromolecule catabolic process 2.1762E-3 2 294 2 6292
    reproduction 2.7096E-3 2 328 2 6292
    developmental process 2.7595E-3 2 331 2 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    cellular catabolic process 4.3405E-3 2 415 2 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    catabolic process 6.2027E-3 2 496 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    cell cycle 6.95E-3 2 525 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    double-strand/single-strand DNA junction binding 1.5158E-7 2 3 2 6292
    loop DNA binding 1.5158E-7 2 3 2 6292
    Y-form DNA binding 1.5158E-7 2 3 2 6292
    mismatched DNA binding 5.0527E-7 2 5 2 6292
    DNA insertion or deletion binding 5.0527E-7 2 5 2 6292
    DNA secondary structure binding 1.819E-6 2 9 2 6292
    double-stranded DNA binding 1.2783E-5 2 23 2 6292
    structure-specific DNA binding 4.7798E-5 2 44 2 6292
    single base insertion or deletion binding 6.3568E-4 2 2 1 6292
    guanine/thymine mispair binding 9.5344E-4 2 3 1 6292
    four-way junction DNA binding 1.2712E-3 2 4 1 6292
    DNA binding 1.6492E-3 2 256 2 6292
    ATP binding 7.6148E-3 2 24 1 6292
    adenyl ribonucleotide binding 7.9314E-3 2 25 1 6292
    adenyl nucleotide binding 9.5139E-3 2 30 1 6292
    purine nucleoside binding 9.8303E-3 2 31 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle