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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 15 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RET1
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB5
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB8
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC11
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC17
  • DNA-directed RNA polymerase III complex
    		•
  • transcription initiation from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC19
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC25
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC31
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC34
  • nucleus
  • cytoplasm
  • mitochondrion
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC37
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC40
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC53
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC82
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO26
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO31
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA-directed RNA polymerase III complex 1.8856E-43 15 17 15 6292
    RNA polymerase complex 4.167E-37 15 31 15 6292
    nuclear DNA-directed RNA polymerase complex 4.167E-37 15 31 15 6292
    DNA-directed RNA polymerase complex 4.167E-37 15 31 15 6292
    nucleoplasm part 4.7098E-22 15 245 15 6292
    nucleoplasm 1.4911E-21 15 264 15 6292
    nuclear lumen 5.8229E-18 15 453 15 6292
    organelle lumen 1.7741E-15 15 660 15 6292
    intracellular organelle lumen 1.7741E-15 15 660 15 6292
    membrane-enclosed lumen 4.3281E-15 15 700 15 6292
    nuclear part 4.193E-12 15 1103 15 6292
    protein complex 6.6306E-12 15 1137 15 6292
    DNA-directed RNA polymerase I complex 7.2404E-11 15 14 5 6292
    macromolecular complex 1.5857E-9 15 1635 15 6292
    nucleolar part 4.2402E-8 15 45 5 6292
    nucleus 4.4738E-8 15 2041 15 6292
    organelle part 2.3996E-7 15 2282 15 6292
    intracellular organelle part 2.3996E-7 15 2282 15 6292
    DNA-directed RNA polymerase II, core complex 2.3814E-6 15 12 3 6292
    nucleolus 9.2283E-5 15 211 5 6292
    DNA-directed RNA polymerase II, holoenzyme 2.8171E-4 15 56 3 6292
    membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    intracellular membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    intracellular organelle 1.4392E-3 15 4070 15 6292
    organelle 1.4445E-3 15 4071 15 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription from RNA polymerase III promoter 2.1451E-35 15 38 15 6292
    transcription, DNA-dependent 2.8668E-17 15 503 15 6292
    RNA biosynthetic process 3.3323E-17 15 508 15 6292
    transcription 1.1781E-16 15 552 15 6292
    RNA metabolic process 4.6839E-13 15 954 15 6292
    cellular macromolecule biosynthetic process 1.2694E-11 15 1187 15 6292
    macromolecule biosynthetic process 1.3021E-11 15 1189 15 6292
    gene expression 4.1034E-11 15 1283 15 6292
    nucleic acid metabolic process 1.7965E-10 15 1415 15 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.2811E-10 15 1566 15 6292
    cellular biosynthetic process 8.3612E-10 15 1567 15 6292
    biosynthetic process 1.1663E-9 15 1602 15 6292
    transcription from RNA polymerase I promoter 5.0454E-9 15 30 5 6292
    cellular nitrogen compound metabolic process 5.2383E-9 15 1770 15 6292
    nitrogen compound metabolic process 6.2564E-9 15 1791 15 6292
    cellular macromolecule metabolic process 2.4475E-7 15 2285 15 6292
    macromolecule metabolic process 3.7086E-7 15 2349 15 6292
    primary metabolic process 8.6423E-6 15 2896 15 6292
    cellular metabolic process 1.7316E-5 15 3033 15 6292
    metabolic process 3.1628E-5 15 3157 15 6292
    cellular process 5.0732E-3 15 4426 15 6292
    ribosome biogenesis 7.5613E-3 15 346 4 6292
    ribonucleoprotein complex biogenesis 9.9288E-3 15 374 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase activity 2.5733E-36 15 34 15 6292
    DNA-directed RNA polymerase activity 2.5733E-36 15 34 15 6292
    nucleotidyltransferase activity 1.3349E-24 15 168 15 6292
    transferase activity, transferring phosphorus-containing groups 1.8379E-18 15 420 15 6292
    transferase activity 3.0884E-14 15 797 15 6292
    catalytic activity 9.7891E-8 15 2150 15 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle