YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CBF5
  • box H/ACA snoRNP complex
  • nuclear outer membrane
  • nucleolus
  • rRNA pseudouridine synthesis
  • ribosome biogenesis
  • pseudouridylate synthase activity
  • HAS1
  • nuclear envelope
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA binding
  • RNA-dependent ATPase activity
  • ATP-dependent RNA helicase activity
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP56
  • box C/D snoRNP complex
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • RRP12
  • nucleus
  • ribosome
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 3.5178E-9 7 72 5 6292
    nuclear envelope 6.0065E-7 7 199 5 6292
    nucleolus 8.0465E-7 7 211 5 6292
    nuclear outer membrane 1.1039E-6 7 86 4 6292
    nuclear membrane 1.7936E-6 7 97 4 6292
    ribonucleoprotein complex 1.8849E-6 7 514 6 6292
    endomembrane system 1.8664E-5 7 398 5 6292
    outer membrane 2.0283E-5 7 178 4 6292
    organelle outer membrane 2.0283E-5 7 178 4 6292
    nuclear lumen 3.5214E-5 7 453 5 6292
    nuclear membrane-endoplasmic reticulum network 5.7767E-5 7 232 4 6292
    envelope 5.9882E-5 7 505 5 6292
    organelle envelope 5.9882E-5 7 505 5 6292
    non-membrane-bounded organelle 7.5345E-5 7 959 6 6292
    intracellular non-membrane-bounded organelle 7.5345E-5 7 959 6 6292
    organelle lumen 2.1944E-4 7 660 5 6292
    intracellular organelle lumen 2.1944E-4 7 660 5 6292
    membrane-enclosed lumen 2.9135E-4 7 700 5 6292
    nucleolar part 1.0268E-3 7 45 2 6292
    macromolecular complex 1.6651E-3 7 1635 6 6292
    box C/D snoRNP complex 2.224E-3 7 2 1 6292
    box H/ACA snoRNP complex 2.224E-3 7 2 1 6292
    nuclear part 2.5214E-3 7 1103 5 6292
    membrane part 3.276E-3 7 662 4 6292
    organelle membrane 3.8647E-3 7 692 4 6292
    nucleus 5.8629E-3 7 2041 6 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    rRNA processing 1.2244E-12 7 128 7 6292
    rRNA metabolic process 1.9922E-12 7 137 7 6292
    ncRNA processing 4.9448E-11 7 215 7 6292
    ncRNA metabolic process 1.7526E-10 7 257 7 6292
    maturation of SSU-rRNA 1.2631E-9 7 59 5 6292
    ribosome biogenesis 1.4353E-9 7 346 7 6292
    ribonucleoprotein complex biogenesis 2.486E-9 7 374 7 6292
    RNA processing 2.7815E-9 7 380 7 6292
    cellular component biogenesis 1.9331E-7 7 694 7 6292
    rRNA modification 6.8335E-7 7 18 3 6292
    RNA metabolic process 1.8079E-6 7 954 7 6292
    gene expression 1.4468E-5 7 1283 7 6292
    nucleic acid metabolic process 2.8759E-5 7 1415 7 6292
    RNA modification 4.4713E-5 7 70 3 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5.8565E-5 7 1566 7 6292
    cellular nitrogen compound metabolic process 1.3822E-4 7 1770 7 6292
    nitrogen compound metabolic process 1.5014E-4 7 1791 7 6292
    cellular macromolecule metabolic process 8.282E-4 7 2285 7 6292
    macromolecule metabolic process 1.0051E-3 7 2349 7 6292
    ncRNA 5'-end processing 3.3344E-3 7 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.3344E-3 7 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.3344E-3 7 3 1 6292
    rRNA 5'-end processing 3.3344E-3 7 3 1 6292
    RNA 5'-end processing 3.3344E-3 7 3 1 6292
    primary metabolic process 4.3588E-3 7 2896 7 6292
    rRNA pseudouridine synthesis 4.4437E-3 7 4 1 6292
    maturation of 5.8S rRNA 4.4437E-3 7 4 1 6292
    cleavage involved in rRNA processing 4.4437E-3 7 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.4437E-3 7 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.4437E-3 7 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 4.4437E-3 7 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.4437E-3 7 4 1 6292
    snoRNA 3'-end processing 5.552E-3 7 5 1 6292
    cellular metabolic process 6.026E-3 7 3033 7 6292
    snoRNA processing 7.7654E-3 7 7 1 6292
    metabolic process 7.9792E-3 7 3157 7 6292
    pseudouridine synthesis 9.9746E-3 7 9 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 4.8586E-4 7 31 2 6292
    pseudouridylate synthase activity 5.552E-3 7 5 1 6292
    RNA binding 5.7756E-3 7 367 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle