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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
IMD1
IMD3
  • cytoplasm
  • GTP biosynthetic process
  • IMP dehydrogenase activity
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPP0
  • ribosomal large subunit assembly
  • translational elongation
  • translation
  • structural constituent of ribosome
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.8934E-5 11 101 4 6292
    preribosome 2.31E-5 11 34 3 6292
    cytosolic part 3.997E-5 11 122 4 6292
    ribonucleoprotein complex 9.3452E-5 11 514 6 6292
    ribosomal subunit 1.9471E-4 11 183 4 6292
    90S preribosome 3.7257E-4 11 17 2 6292
    cytosol 1.0424E-3 11 284 4 6292
    ribosome 1.1276E-3 11 290 4 6292
    cytosolic small ribosomal subunit 1.8876E-3 11 38 2 6292
    non-membrane-bounded organelle 2.8626E-3 11 959 6 6292
    intracellular non-membrane-bounded organelle 2.8626E-3 11 959 6 6292
    cytosolic large ribosomal subunit 4.6539E-3 11 60 2 6292
    nucleolus 5.0257E-3 11 211 3 6292
    small ribosomal subunit 6.8247E-3 11 73 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 6.9E-7 11 376 7 6292
    ribosome biogenesis 9.6734E-6 11 346 6 6292
    ribonucleoprotein complex biogenesis 1.5174E-5 11 374 6 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.145E-4 11 13 2 6292
    gene expression 2.6734E-4 11 1283 8 6292
    cellular component biogenesis 4.9969E-4 11 694 6 6292
    cellular protein metabolic process 7.2248E-4 11 1074 7 6292
    protein metabolic process 1.0289E-3 11 1136 7 6292
    cellular biosynthetic process 1.1444E-3 11 1567 8 6292
    biosynthetic process 1.3405E-3 11 1602 8 6292
    cellular macromolecule biosynthetic process 1.3543E-3 11 1187 7 6292
    macromolecule biosynthetic process 1.3686E-3 11 1189 7 6292
    ribosomal large subunit assembly 2.1955E-3 11 41 2 6292
    GTP biosynthetic process 3.4937E-3 11 2 1 6292
    ribosomal subunit assembly 3.9232E-3 11 55 2 6292
    maturation of SSU-rRNA 4.5031E-3 11 59 2 6292
    ribosome assembly 5.2805E-3 11 64 2 6292
    ribosomal large subunit biogenesis 5.443E-3 11 65 2 6292
    organelle assembly 6.1157E-3 11 69 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.3154E-8 11 212 7 6292
    structural molecule activity 3.3934E-7 11 339 7 6292
    IMP dehydrogenase activity 5.2364E-3 11 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle