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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
DIM1
  • nuclear outer membrane
  • nucleolus
  • rRNA modification
  • ribosome biogenesis
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • preribosome, small subunit precursor
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • PNO1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • protein complex assembly
  • ribosome biogenesis
  • rRNA processing
  • unfolded protein binding
  • RRP12
  • nucleus
  • ribosome
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP8
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 6.0718E-12 11 72 7 6292
    nuclear outer membrane 2.1973E-11 11 86 7 6292
    nuclear membrane 5.2209E-11 11 97 7 6292
    outer membrane 3.8696E-9 11 178 7 6292
    organelle outer membrane 3.8696E-9 11 178 7 6292
    ribonucleoprotein complex 7.1884E-9 11 514 9 6292
    nuclear envelope 8.4534E-9 11 199 7 6292
    nucleolus 1.2727E-8 11 211 7 6292
    nuclear membrane-endoplasmic reticulum network 2.4656E-8 11 232 7 6292
    endomembrane system 1.0173E-6 11 398 7 6292
    nuclear lumen 2.453E-6 11 453 7 6292
    envelope 5.1136E-6 11 505 7 6292
    organelle envelope 5.1136E-6 11 505 7 6292
    preribosome 2.31E-5 11 34 3 6292
    non-membrane-bounded organelle 3.0414E-5 11 959 8 6292
    intracellular non-membrane-bounded organelle 3.0414E-5 11 959 8 6292
    organelle lumen 3.0633E-5 11 660 7 6292
    intracellular organelle lumen 3.0633E-5 11 660 7 6292
    membrane part 3.1254E-5 11 662 7 6292
    preribosome, small subunit precursor 4.1526E-5 11 6 2 6292
    organelle membrane 4.1907E-5 11 692 7 6292
    membrane-enclosed lumen 4.5212E-5 11 700 7 6292
    nuclear part 8.708E-5 11 1103 8 6292
    macromolecular complex 1.7215E-4 11 1635 9 6292
    nucleus 1.0879E-3 11 2041 9 6292
    membrane 1.4344E-3 11 1198 7 6292
    nucleolar part 2.6406E-3 11 45 2 6292
    Noc4p-Nop14p complex 3.4937E-3 11 2 1 6292
    RENT complex 6.9763E-3 11 4 1 6292
    Noc complex 8.7135E-3 11 5 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 1.1946E-14 11 346 11 6292
    rRNA processing 2.392E-14 11 128 9 6292
    ribonucleoprotein complex biogenesis 2.846E-14 11 374 11 6292
    rRNA metabolic process 4.4834E-14 11 137 9 6292
    ncRNA processing 2.7925E-12 11 215 9 6292
    ncRNA metabolic process 1.4132E-11 11 257 9 6292
    cellular component biogenesis 2.7383E-11 11 694 11 6292
    RNA processing 4.8187E-10 11 380 9 6292
    maturation of SSU-rRNA 2.7001E-8 11 59 5 6292
    RNA metabolic process 1.6866E-6 11 954 9 6292
    gene expression 2.1916E-5 11 1283 9 6292
    nucleic acid metabolic process 5.063E-5 11 1415 9 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.1968E-4 11 1566 9 6292
    cellular nitrogen compound metabolic process 3.347E-4 11 1770 9 6292
    nitrogen compound metabolic process 3.6929E-4 11 1791 9 6292
    ribosomal small subunit biogenesis 8.8271E-4 11 26 2 6292
    cellular macromolecule metabolic process 2.7237E-3 11 2285 9 6292
    macromolecule metabolic process 3.4003E-3 11 2349 9 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 9.3712E-10 11 31 5 6292
    RNA binding 2.2654E-4 11 367 5 6292
    rRNA (adenine-N6,N6-)-dimethyltransferase activity 1.7483E-3 11 1 1 6292
    rRNA (adenine) methyltransferase activity 1.7483E-3 11 1 1 6292
    nucleic acid binding 3.5073E-3 11 666 5 6292
    rRNA methyltransferase activity 8.7135E-3 11 5 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle