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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.599261486969]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
ELA1
  • transcription elongation factor complex
  • Cul3-RING ubiquitin ligase complex
    		•
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • RNA elongation from RNA polymerase II promoter
    		•
  • transcription elongation regulator activity
    		•
    ELC1
  • transcription elongation factor complex
  • Cul3-RING ubiquitin ligase complex
  • nucleotide-excision repair factor 4 complex
    		•
  • nucleotide-excision repair, DNA damage recognition
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • RNA elongation from RNA polymerase II promoter
    		•
  • transcription elongation regulator activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Cul3-RING ubiquitin ligase complex 3.0316E-7 2 4 2 6292
    cullin-RING ubiquitin ligase complex 4.5979E-6 2 14 2 6292
    transcription elongation factor complex 1.2783E-5 2 23 2 6292
    ubiquitin ligase complex 4.5626E-5 2 43 2 6292
    nucleotide-excision repair factor 4 complex 1.2712E-3 2 4 1 6292
    nucleoplasm part 1.5102E-3 2 245 2 6292
    nucleoplasm 1.7541E-3 2 264 2 6292
    nuclear lumen 5.1728E-3 2 453 2 6292
    nucleotide-excision repair complex 6.6645E-3 2 21 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein ubiquitination during ubiquitin-dependent protein catabolic process 2.779E-6 2 11 2 6292
    RNA elongation from RNA polymerase II promoter 3.744E-5 2 39 2 6292
    RNA elongation 5.0022E-5 2 45 2 6292
    protein ubiquitination 1.051E-4 2 65 2 6292
    protein modification by small protein conjugation 1.8468E-4 2 86 2 6292
    protein modification by small protein conjugation or removal 3.2544E-4 2 114 2 6292
    modification-dependent protein catabolic process 6.1087E-4 2 156 2 6292
    ubiquitin-dependent protein catabolic process 6.1087E-4 2 156 2 6292
    proteolysis involved in cellular protein catabolic process 6.3467E-4 2 159 2 6292
    modification-dependent macromolecule catabolic process 6.7534E-4 2 164 2 6292
    cellular protein catabolic process 7.3441E-4 2 171 2 6292
    proteolysis 8.8816E-4 2 188 2 6292
    protein catabolic process 8.9766E-4 2 189 2 6292
    cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
    macromolecule catabolic process 2.1762E-3 2 294 2 6292
    nucleotide-excision repair, DNA damage recognition 2.224E-3 2 7 1 6292
    transcription from RNA polymerase II promoter 2.8267E-3 2 335 2 6292
    post-translational protein modification 3.2108E-3 2 357 2 6292
    cellular catabolic process 4.3405E-3 2 415 2 6292
    catabolic process 6.2027E-3 2 496 2 6292
    protein modification process 6.278E-3 2 499 2 6292
    transcription, DNA-dependent 6.3792E-3 2 503 2 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    transcription 7.6839E-3 2 552 2 6292
    macromolecule modification 8.1649E-3 2 569 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription elongation regulator activity 8.6401E-6 2 19 2 6292
    transcription regulator activity 2.8947E-3 2 339 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle